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The map label for this gene is tagO [H]

Identifier: 52140365

GI number: 52140365

Start: 4983675

End: 4984748

Strand: Direct

Name: tagO [H]

Synonym: BCZK4895

Alternate gene names: 52140365

Gene position: 4983675-4984748 (Clockwise)

Preceding gene: 52140367

Following gene: 52140364

Centisome position: 94.02

GC content: 36.13

Gene sequence:

>1074_bases
ATGGACTCACAAGTGATTTATGCCATTTTGGCATCTTTCATCACTGTACTCGTCGTTACTCCTTTAGTTATTAAGTTAGC
TTTTAAAATAGGAGCAACAGATAAGCCAAACGCACGTAAAGTGCACCAAAAGATTATGCCTCGTCTTGGCGGGTTAGCGA
TATTTATTGGTGTGGCTGTTGGATTTGTTGTTGGTGGCTTATACGAACAAAGAATGTTATCGATAACGCTAGGTGCGATT
ATCATTGTAATCATCGGTATTTTAGATGATATGTACGAGTTATCTGCGAAGGTAAAATTCGGTGGACAACTATTAGTTGC
CATTATGATTGTAAAAAGTGGATTATTAGTGCAAGTATTATATATTCCAATCCTCGGGGATACTGAACTTGGATGGCTCG
CTTACCCAATTACAGTATTTTGGATTGTAGGTATTACAAATGCTATCAACTTAATTGATGGCTTAGATGGATTATCTGCT
GGTATTTCATCTATCGTACTTGCAACGCTAGCATATATGGCCTTCACTAGCCCATGGGGCACTGGAACAGCTATCATTTT
ACCTCTAGCACTCATTGCACTTGCAAGTACAATTGGATTTTTATTCTACAACTTCCATCCAGCAAAAATTTTCATGGGAG
ATACAGGAGCACTATTTTTAGGATACTGTATTTCTGTTATATCGTTACTTGGATTATACAAAAGTGTAACGTTATTCAGC
TTTATCGTTCCAGTTATCATTTTAGGCGTACCTGTATTTGATACGACATTTGCAATTATCCGTCGTATCGTAAATAAAAA
ACCTATTTCAGCACCAGATAAATCGCATTTACATCACCGTTTACTTGCAATGGGCTTCTCTCATCGTAAAACGGTACTAA
TTATATACGCATTTGGTATTTTCTTTAGTGTAAATGCAATCATTTTCTCTAGTGCGACATTATGGTTATCCATTATTCTT
CTTTTCGTTTTAATCTTCTTTACAGAGATTATTGCTGAAGTAATCGGGCTTGTACACGAACGTTACAAACCACTTATTTC
CTTTTATAAAAAAGTGAAAAAACGCGAAGACTAA

Upstream 100 bases:

>100_bases
TTTGTGATACCATATGTTATGAGCCTGTAAATAAACATCATAATTTTCAGATAAATATATTAAAAAAAATTACGTTAGAC
TATAAAAGGGTGGGGTATTA

Downstream 100 bases:

>100_bases
TTGTAGTATAGCCTTTACTATTATGAAATATTCAAATAGCATCCTCTTTCTTATAAGAGGATGCTATTTTTTATTCATTA
TTTTATATTTCCAAAATATA

Product: glycosyl transferase, group 4 family protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MDSQVIYAILASFITVLVVTPLVIKLAFKIGATDKPNARKVHQKIMPRLGGLAIFIGVAVGFVVGGLYEQRMLSITLGAI
IIVIIGILDDMYELSAKVKFGGQLLVAIMIVKSGLLVQVLYIPILGDTELGWLAYPITVFWIVGITNAINLIDGLDGLSA
GISSIVLATLAYMAFTSPWGTGTAIILPLALIALASTIGFLFYNFHPAKIFMGDTGALFLGYCISVISLLGLYKSVTLFS
FIVPVIILGVPVFDTTFAIIRRIVNKKPISAPDKSHLHHRLLAMGFSHRKTVLIIYAFGIFFSVNAIIFSSATLWLSIIL
LFVLIFFTEIIAEVIGLVHERYKPLISFYKKVKKRED

Sequences:

>Translated_357_residues
MDSQVIYAILASFITVLVVTPLVIKLAFKIGATDKPNARKVHQKIMPRLGGLAIFIGVAVGFVVGGLYEQRMLSITLGAI
IIVIIGILDDMYELSAKVKFGGQLLVAIMIVKSGLLVQVLYIPILGDTELGWLAYPITVFWIVGITNAINLIDGLDGLSA
GISSIVLATLAYMAFTSPWGTGTAIILPLALIALASTIGFLFYNFHPAKIFMGDTGALFLGYCISVISLLGLYKSVTLFS
FIVPVIILGVPVFDTTFAIIRRIVNKKPISAPDKSHLHHRLLAMGFSHRKTVLIIYAFGIFFSVNAIIFSSATLWLSIIL
LFVLIFFTEIIAEVIGLVHERYKPLISFYKKVKKRED
>Mature_357_residues
MDSQVIYAILASFITVLVVTPLVIKLAFKIGATDKPNARKVHQKIMPRLGGLAIFIGVAVGFVVGGLYEQRMLSITLGAI
IIVIIGILDDMYELSAKVKFGGQLLVAIMIVKSGLLVQVLYIPILGDTELGWLAYPITVFWIVGITNAINLIDGLDGLSA
GISSIVLATLAYMAFTSPWGTGTAIILPLALIALASTIGFLFYNFHPAKIFMGDTGALFLGYCISVISLLGLYKSVTLFS
FIVPVIILGVPVFDTTFAIIRRIVNKKPISAPDKSHLHHRLLAMGFSHRKTVLIIYAFGIFFSVNAIIFSSATLWLSIIL
LFVLIFFTEIIAEVIGLVHERYKPLISFYKKVKKRED

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=277, Percent_Identity=28.5198555956679, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 39040; Mature: 39040

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSQVIYAILASFITVLVVTPLVIKLAFKIGATDKPNARKVHQKIMPRLGGLAIFIGVAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GFVVGGLYEQRMLSITLGAIIIVIIGILDDMYELSAKVKFGGQLLVAIMIVKSGLLVQVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
YIPILGDTELGWLAYPITVFWIVGITNAINLIDGLDGLSAGISSIVLATLAYMAFTSPWG
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
TGTAIILPLALIALASTIGFLFYNFHPAKIFMGDTGALFLGYCISVISLLGLYKSVTLFS
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
FIVPVIILGVPVFDTTFAIIRRIVNKKPISAPDKSHLHHRLLAMGFSHRKTVLIIYAFGI
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHH
FFSVNAIIFSSATLWLSIILLFVLIFFTEIIAEVIGLVHERYKPLISFYKKVKKRED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDSQVIYAILASFITVLVVTPLVIKLAFKIGATDKPNARKVHQKIMPRLGGLAIFIGVAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GFVVGGLYEQRMLSITLGAIIIVIIGILDDMYELSAKVKFGGQLLVAIMIVKSGLLVQVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHH
YIPILGDTELGWLAYPITVFWIVGITNAINLIDGLDGLSAGISSIVLATLAYMAFTSPWG
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
TGTAIILPLALIALASTIGFLFYNFHPAKIFMGDTGALFLGYCISVISLLGLYKSVTLFS
CCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
FIVPVIILGVPVFDTTFAIIRRIVNKKPISAPDKSHLHHRLLAMGFSHRKTVLIIYAFGI
HHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCEEHHHHHHH
FFSVNAIIFSSATLWLSIILLFVLIFFTEIIAEVIGLVHERYKPLISFYKKVKKRED
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]