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The map label for this gene is dnaC [H]

Identifier: 51894449

GI number: 51894449

Start: 3543136

End: 3544476

Strand: Reverse

Name: dnaC [H]

Synonym: STH3315

Alternate gene names: 51894449

Gene position: 3544476-3543136 (Counterclockwise)

Preceding gene: 51894450

Following gene: 51894448

Centisome position: 99.39

GC content: 66.67

Gene sequence:

>1341_bases
GTGAACGCCTTCAGTGAGCGGGTTCCACCCCAGAACCTCGAGGCGGAGCAGTCTGTCCTGGGCGCAATGCTGATCGACCG
GGAGGCGGTGGTCGCCGTCGCCCACAAGCTGGTGCCCGAGGACTTTTACGCCGACCGGCACCAGCACCTGTTCGCCGCCA
TGCTCGCGCTGTACAACCGCGGGGAGCCGGTGGATCCGATCACGGTGCAGGACGAGCTCATCCGCACCGGCCAGCTGGAG
GAGGTGGGCGGGCTCACCTACCTGACGAGCCTGATCAACCTGGTGCCCACCACCGCCAACGTCCTGCAGTATGCGGAGAT
CGTGGAGTCGAAGGCGATTCTCCGCCGGCTGCAGACGGCGGCGCGGCGCATCGTGGACGAGTGCTACATCGCGGAGGATG
TGGACCAGACGCTGCAGGAGGCGGAGAAGTCGATCTTCGCCGTGACCCAGCGCCGGTCCGCCCGGGGGTACCTGCACATC
CGCGACGCCCTGGTCACCGCCTACGGCCACCTGGAGCATCTCTACTCCACCAAGGGCCGGACCACCGGCGTACCTTCCGG
CTACCGGGACCTGGACGCGATGACGTCGGGCTTTCAGCCCTCGGACCTGATCATCGTCGCCGCACGCCCGTCGGTGGGCA
AGACCGCCTTCACCCTCAACATCGCGCGCAACGCCGCGGTGCAGGCCAAAGCGAAGGTGATCTTTTTCTCCCTGGAGATG
TCCGCGGAGCAGCTGGCCCTGCGCCTCCTGGCATCGGAGGCCACGGTGGATGGCCACAAGCTGCGCACCGGGCAACTGCA
GGACCAGGACTGGCACAAGCTGGGCACGGCGCTCTCGGTGCTGGGCGAGAGCGACATCTACATCGACGATACGCCCAACA
TCCCCCTGCAGGAGATGCGGGCGAAGGCGCGCCGGCTGGCGCAGGAGCACGGTCTCGATCTGATCATCGTCGACTACCTG
CAGCTGATGTCGCTGCCCCAGCGGCCGGGGCAGCAGGCCAACCGGCAGCAGGAGATTTCGGAGATCTCCCGGTCGCTGAA
GGCGCTCGCCCGCGAGCTGAAGGTGCCGATCATCGCCCTGTCGCAGCTCTCCCGCTCGGTGGAGCAGCGGCAGGACAAGC
GGCCGATGCTCTCGGACCTGCGTGAATCCGGCGCGCTGGAGCAGGACGCCGACGTGGTCGCGTTCCTCTACCGGGAAGAC
TACTATGACCAGAACACCGACAAGAAGGACATCGTGGAGGTCATCCTGGCCAAGCACCGCAACGGTCCCATCGGCACGGT
GGAGCTGTACTTTGCCAAGGAGATCCAGCGGATGTACGGACGCGAGCAGCGGCGGCAGTAG

Upstream 100 bases:

>100_bases
CGCAGCAGGTGCCGGGCATCGAGGTCTGCTTCGCCTCCACCATCGAGGAGGCGATGCGCCTGGTTATGGCCGCGCCCGGC
GGTGAGGGGGCGAGCTAGCC

Downstream 100 bases:

>100_bases
CCAAGATTCCCGCGACGACGCGCGAATCTTTGACGTCGCGAGTTACGAACATTAGTATCCACAACTGTGGACAACGTTCG
GCCGCTGCATTGACACCGCG

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNAFSERVPPQNLEAEQSVLGAMLIDREAVVAVAHKLVPEDFYADRHQHLFAAMLALYNRGEPVDPITVQDELIRTGQLE
EVGGLTYLTSLINLVPTTANVLQYAEIVESKAILRRLQTAARRIVDECYIAEDVDQTLQEAEKSIFAVTQRRSARGYLHI
RDALVTAYGHLEHLYSTKGRTTGVPSGYRDLDAMTSGFQPSDLIIVAARPSVGKTAFTLNIARNAAVQAKAKVIFFSLEM
SAEQLALRLLASEATVDGHKLRTGQLQDQDWHKLGTALSVLGESDIYIDDTPNIPLQEMRAKARRLAQEHGLDLIIVDYL
QLMSLPQRPGQQANRQQEISEISRSLKALARELKVPIIALSQLSRSVEQRQDKRPMLSDLRESGALEQDADVVAFLYRED
YYDQNTDKKDIVEVILAKHRNGPIGTVELYFAKEIQRMYGREQRRQ

Sequences:

>Translated_446_residues
MNAFSERVPPQNLEAEQSVLGAMLIDREAVVAVAHKLVPEDFYADRHQHLFAAMLALYNRGEPVDPITVQDELIRTGQLE
EVGGLTYLTSLINLVPTTANVLQYAEIVESKAILRRLQTAARRIVDECYIAEDVDQTLQEAEKSIFAVTQRRSARGYLHI
RDALVTAYGHLEHLYSTKGRTTGVPSGYRDLDAMTSGFQPSDLIIVAARPSVGKTAFTLNIARNAAVQAKAKVIFFSLEM
SAEQLALRLLASEATVDGHKLRTGQLQDQDWHKLGTALSVLGESDIYIDDTPNIPLQEMRAKARRLAQEHGLDLIIVDYL
QLMSLPQRPGQQANRQQEISEISRSLKALARELKVPIIALSQLSRSVEQRQDKRPMLSDLRESGALEQDADVVAFLYRED
YYDQNTDKKDIVEVILAKHRNGPIGTVELYFAKEIQRMYGREQRRQ
>Mature_446_residues
MNAFSERVPPQNLEAEQSVLGAMLIDREAVVAVAHKLVPEDFYADRHQHLFAAMLALYNRGEPVDPITVQDELIRTGQLE
EVGGLTYLTSLINLVPTTANVLQYAEIVESKAILRRLQTAARRIVDECYIAEDVDQTLQEAEKSIFAVTQRRSARGYLHI
RDALVTAYGHLEHLYSTKGRTTGVPSGYRDLDAMTSGFQPSDLIIVAARPSVGKTAFTLNIARNAAVQAKAKVIFFSLEM
SAEQLALRLLASEATVDGHKLRTGQLQDQDWHKLGTALSVLGESDIYIDDTPNIPLQEMRAKARRLAQEHGLDLIIVDYL
QLMSLPQRPGQQANRQQEISEISRSLKALARELKVPIIALSQLSRSVEQRQDKRPMLSDLRESGALEQDADVVAFLYRED
YYDQNTDKKDIVEVILAKHRNGPIGTVELYFAKEIQRMYGREQRRQ

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=442, Percent_Identity=47.0588235294118, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 50147; Mature: 50147

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFSERVPPQNLEAEQSVLGAMLIDREAVVAVAHKLVPEDFYADRHQHLFAAMLALYNR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GEPVDPITVQDELIRTGQLEEVGGLTYLTSLINLVPTTANVLQYAEIVESKAILRRLQTA
CCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ARRIVDECYIAEDVDQTLQEAEKSIFAVTQRRSARGYLHIRDALVTAYGHLEHLYSTKGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCC
TTGVPSGYRDLDAMTSGFQPSDLIIVAARPSVGKTAFTLNIARNAAVQAKAKVIFFSLEM
CCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEHHHCHHHHHEEEEEEEEECC
SAEQLALRLLASEATVDGHKLRTGQLQDQDWHKLGTALSVLGESDIYIDDTPNIPLQEMR
CHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHH
AKARRLAQEHGLDLIIVDYLQLMSLPQRPGQQANRQQEISEISRSLKALARELKVPIIAL
HHHHHHHHHCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SQLSRSVEQRQDKRPMLSDLRESGALEQDADVVAFLYREDYYDQNTDKKDIVEVILAKHR
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
NGPIGTVELYFAKEIQRMYGREQRRQ
CCCCCEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAFSERVPPQNLEAEQSVLGAMLIDREAVVAVAHKLVPEDFYADRHQHLFAAMLALYNR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
GEPVDPITVQDELIRTGQLEEVGGLTYLTSLINLVPTTANVLQYAEIVESKAILRRLQTA
CCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
ARRIVDECYIAEDVDQTLQEAEKSIFAVTQRRSARGYLHIRDALVTAYGHLEHLYSTKGR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHCCCC
TTGVPSGYRDLDAMTSGFQPSDLIIVAARPSVGKTAFTLNIARNAAVQAKAKVIFFSLEM
CCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEEHHHCHHHHHEEEEEEEEECC
SAEQLALRLLASEATVDGHKLRTGQLQDQDWHKLGTALSVLGESDIYIDDTPNIPLQEMR
CHHHHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCHHHHH
AKARRLAQEHGLDLIIVDYLQLMSLPQRPGQQANRQQEISEISRSLKALARELKVPIIAL
HHHHHHHHHCCCCEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
SQLSRSVEQRQDKRPMLSDLRESGALEQDADVVAFLYREDYYDQNTDKKDIVEVILAKHR
HHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
NGPIGTVELYFAKEIQRMYGREQRRQ
CCCCCEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]