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The map label for this gene is coaX2

Identifier: 51894319

GI number: 51894319

Start: 3392615

End: 3393409

Strand: Reverse

Name: coaX2

Synonym: STH3184

Alternate gene names: 51894319

Gene position: 3393409-3392615 (Counterclockwise)

Preceding gene: 51894320

Following gene: 51894318

Centisome position: 95.16

GC content: 67.42

Gene sequence:

>795_bases
ATGCTGCTCACCATTGACGTCGGGAACACATTCACGGTCGCCGGCGTGTTCGAGGGTCAGAACCTGCTGGCGGAATGGAC
GGTGACCACCGATCCGAACCGCACCATGGACGAGTACGGGATGCTGTTCACCCAGCTGATGGCGCGCGCCGGCTTTTCAT
CCGGCCAGGTGACGGCCGTGGCCATCGCGTCCTCGGTCCCGCCGCTGGTCCCCACGCTCGAGTGGATGTGCCAGAAGTAC
TTCAACCTGAAGCCGCTGGTGGTCGGTCCCGGCGTCCGCACCGGCATGATGATCCGGTACGACAACCCGCGCGAGGTGGG
GGCGGACCGGATCGTGGGCGCAGTGGCGGCCTTTGACAAGTACGGCGGGCCGCTGATCGTGGTGGACTTCAGCACCGCCA
TCATCCTCGACGCCATCTCCGCCCGGGGAGAGTACCTGGGCGGCGTGATCGCGCCCGGGATTGTCGTCTCGGCCGACGCG
CTGTTCCAGTTCGCTGCCAAGCTGCCCCGGGTCGAGCTGGTCCGGCCGCCGCGGGCCCTGGCCCGGAACACGGTCCACGC
CATGCAGTCGGGGATCATCTTCGGCTTCGCCAGTCTGGTGGACGACCTGGTGGAGCGCATGATGGCCGAACTGGATCCGG
AGGGAAAGGGGTGCAAGGTCGTCGCGACCGGCGAGCAGGCAGAGCTGCTGGCCGGCGAGTGCGCGACGATCCAGTACTGC
GATCCCTCCCTCACGTTGACCGGACTGCGCATCATCTACGAACGGCACCAGGCCCACGCCCGGGGGGGAAGGTAG

Upstream 100 bases:

>100_bases
TTGACCCGGGCCGCATGCAGTCATGCTATAATCGTCCATGAGTTTTCGTGGAGCCGGGCCCGCACCGGAGCAGGCCGGCC
ACCGGGGAGGTCGCGCACGG

Downstream 100 bases:

>100_bases
CCCATGCTGCTCGCTGTCGACATCGGGAACACCAACATTACCGCGGGGCTCTTCCTGGAGGATGAGCTCATCTGCATGTG
GCGGATGGCCTCCAACCGCG

Product: putative transcriptional regulator Bvg accessory factor

Products: NA

Alternate protein names: PanK-III 2; Pantothenic acid kinase 2

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MLLTIDVGNTFTVAGVFEGQNLLAEWTVTTDPNRTMDEYGMLFTQLMARAGFSSGQVTAVAIASSVPPLVPTLEWMCQKY
FNLKPLVVGPGVRTGMMIRYDNPREVGADRIVGAVAAFDKYGGPLIVVDFSTAIILDAISARGEYLGGVIAPGIVVSADA
LFQFAAKLPRVELVRPPRALARNTVHAMQSGIIFGFASLVDDLVERMMAELDPEGKGCKVVATGEQAELLAGECATIQYC
DPSLTLTGLRIIYERHQAHARGGR

Sequences:

>Translated_264_residues
MLLTIDVGNTFTVAGVFEGQNLLAEWTVTTDPNRTMDEYGMLFTQLMARAGFSSGQVTAVAIASSVPPLVPTLEWMCQKY
FNLKPLVVGPGVRTGMMIRYDNPREVGADRIVGAVAAFDKYGGPLIVVDFSTAIILDAISARGEYLGGVIAPGIVVSADA
LFQFAAKLPRVELVRPPRALARNTVHAMQSGIIFGFASLVDDLVERMMAELDPEGKGCKVVATGEQAELLAGECATIQYC
DPSLTLTGLRIIYERHQAHARGGR
>Mature_264_residues
MLLTIDVGNTFTVAGVFEGQNLLAEWTVTTDPNRTMDEYGMLFTQLMARAGFSSGQVTAVAIASSVPPLVPTLEWMCQKY
FNLKPLVVGPGVRTGMMIRYDNPREVGADRIVGAVAAFDKYGGPLIVVDFSTAIILDAISARGEYLGGVIAPGIVVSADA
LFQFAAKLPRVELVRPPRALARNTVHAMQSGIIFGFASLVDDLVERMMAELDPEGKGCKVVATGEQAELLAGECATIQYC
DPSLTLTGLRIIYERHQAHARGGR

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX2_SYMTH (Q67JI4)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_077010.1
- ProteinModelPortal:   Q67JI4
- SMR:   Q67JI4
- GeneID:   2979281
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH3184
- NMPDR:   fig|292459.1.peg.3055
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- BioCyc:   STHE292459:STH3184-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28366; Mature: 28366

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTIDVGNTFTVAGVFEGQNLLAEWTVTTDPNRTMDEYGMLFTQLMARAGFSSGQVTAV
CEEEEECCCEEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
AIASSVPPLVPTLEWMCQKYFNLKPLVVGPGVRTGMMIRYDNPREVGADRIVGAVAAFDK
EEECCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEECCCHHHCHHHHHHHHHHHHH
YGGPLIVVDFSTAIILDAISARGEYLGGVIAPGIVVSADALFQFAAKLPRVELVRPPRAL
CCCCEEEEECCHHHHHHHHHHCCHHCCCHHCCCCEEHHHHHHHHHHHCCCEEEECCCHHH
ARNTVHAMQSGIIFGFASLVDDLVERMMAELDPEGKGCKVVATGEQAELLAGECATIQYC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHCCCCCEEEEE
DPSLTLTGLRIIYERHQAHARGGR
CCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLTIDVGNTFTVAGVFEGQNLLAEWTVTTDPNRTMDEYGMLFTQLMARAGFSSGQVTAV
CEEEEECCCEEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
AIASSVPPLVPTLEWMCQKYFNLKPLVVGPGVRTGMMIRYDNPREVGADRIVGAVAAFDK
EEECCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEECCCHHHCHHHHHHHHHHHHH
YGGPLIVVDFSTAIILDAISARGEYLGGVIAPGIVVSADALFQFAAKLPRVELVRPPRAL
CCCCEEEEECCHHHHHHHHHHCCHHCCCHHCCCCEEHHHHHHHHHHHCCCEEEECCCHHH
ARNTVHAMQSGIIFGFASLVDDLVERMMAELDPEGKGCKVVATGEQAELLAGECATIQYC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHCCCCCEEEEE
DPSLTLTGLRIIYERHQAHARGGR
CCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA