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The map label for this gene is coaX1

Identifier: 51894318

GI number: 51894318

Start: 3391805

End: 3392611

Strand: Reverse

Name: coaX1

Synonym: STH3183

Alternate gene names: 51894318

Gene position: 3392611-3391805 (Counterclockwise)

Preceding gene: 51894319

Following gene: 51894317

Centisome position: 95.13

GC content: 69.52

Gene sequence:

>807_bases
ATGCTGCTCGCTGTCGACATCGGGAACACCAACATTACCGCGGGGCTCTTCCTGGAGGATGAGCTCATCTGCATGTGGCG
GATGGCCTCCAACCGCGCGGAGACCTGGGACGAATACGGGCTGCAGCTGATCCAGCTGCTGGAGCGGGACGGACACACGC
CCGCGGACATCACCTGCGCGGCGATGGCCTCCGTGGTGCCACCGCTCAACCCCGTCCTCAGCCGGGCGGTGCAGCAGTAC
CTGAAGGTGCAGTTGAAGGAGCTGACCGGCGACCTGCGCAGCCTGCCGGCGGTCCGGTACGACAACCCCGCCGCCCTGGG
CACCGATCGCCTGGTCAACGCCCTGGCTGGCTGGGAGATCTACGGGCGGCCCCAGGGGCGGCCGGTCATCGTGGTGGACT
TCGGCACCGCCACCAAGCTGGAGTGCGTGAGCGCCGAGGGGGAGTACCTGGGCGGCGTGATCGCGCCCGGCATCCGCACC
GCCGCCGAAGCGCTGACCCGCAGGACGGCCCTGCTGCAGCGGGTGGAGATCCAGCGGCCCAAGTCGGTGATCGGCCGGAA
CATCGCCGCCAGCATGCAGTCGGGGATTCTTTACGGCTTTGCCGGCCTGGCTGACGGCCTGGTGCGCCGGCTGACGCAGG
AGATCGCACCAGACGGCCCCGATCCCGTGGTCGTGGCGACGGGCGGGCTCGCCTCGATGGTCGCGGTGGAAAGCCGGACG
ATCCAGATGGTCGACCCGCACCTCACCCTCCAGGGGATCCGCCTGATGTACGAGTTGAACTGGCCGGACGCCGCGGCGGA
GGCGTAG

Upstream 100 bases:

>100_bases
GTGCGCGACGATCCAGTACTGCGATCCCTCCCTCACGTTGACCGGACTGCGCATCATCTACGAACGGCACCAGGCCCACG
CCCGGGGGGGAAGGTAGCCC

Downstream 100 bases:

>100_bases
GCCGGCGGGGAAGGAAAGGGCGAGCGCTCGGGCGAAACAGTGGCGTAGCGGTACACATCCAAAATCCAGCCAACGGAGGT
ACTCCATGACCAGCTTGCGA

Product: putative transcriptional regulator Bvg accessory factor

Products: NA

Alternate protein names: PanK-III 1; Pantothenic acid kinase 1

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLLAVDIGNTNITAGLFLEDELICMWRMASNRAETWDEYGLQLIQLLERDGHTPADITCAAMASVVPPLNPVLSRAVQQY
LKVQLKELTGDLRSLPAVRYDNPAALGTDRLVNALAGWEIYGRPQGRPVIVVDFGTATKLECVSAEGEYLGGVIAPGIRT
AAEALTRRTALLQRVEIQRPKSVIGRNIAASMQSGILYGFAGLADGLVRRLTQEIAPDGPDPVVVATGGLASMVAVESRT
IQMVDPHLTLQGIRLMYELNWPDAAAEA

Sequences:

>Translated_268_residues
MLLAVDIGNTNITAGLFLEDELICMWRMASNRAETWDEYGLQLIQLLERDGHTPADITCAAMASVVPPLNPVLSRAVQQY
LKVQLKELTGDLRSLPAVRYDNPAALGTDRLVNALAGWEIYGRPQGRPVIVVDFGTATKLECVSAEGEYLGGVIAPGIRT
AAEALTRRTALLQRVEIQRPKSVIGRNIAASMQSGILYGFAGLADGLVRRLTQEIAPDGPDPVVVATGGLASMVAVESRT
IQMVDPHLTLQGIRLMYELNWPDAAAEA
>Mature_268_residues
MLLAVDIGNTNITAGLFLEDELICMWRMASNRAETWDEYGLQLIQLLERDGHTPADITCAAMASVVPPLNPVLSRAVQQY
LKVQLKELTGDLRSLPAVRYDNPAALGTDRLVNALAGWEIYGRPQGRPVIVVDFGTATKLECVSAEGEYLGGVIAPGIRT
AAEALTRRTALLQRVEIQRPKSVIGRNIAASMQSGILYGFAGLADGLVRRLTQEIAPDGPDPVVVATGGLASMVAVESRT
IQMVDPHLTLQGIRLMYELNWPDAAAEA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX1_SYMTH (Q67JI5)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_077009.1
- ProteinModelPortal:   Q67JI5
- SMR:   Q67JI5
- GeneID:   2979377
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH3183
- NMPDR:   fig|292459.1.peg.3054
- HOGENOM:   HBG634537
- OMA:   GTACTIF
- BioCyc:   STHE292459:STH3183-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28917; Mature: 28917

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAVDIGNTNITAGLFLEDELICMWRMASNRAETWDEYGLQLIQLLERDGHTPADITCA
CEEEEEECCCCEEEEEEECCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
AMASVVPPLNPVLSRAVQQYLKVQLKELTGDLRSLPAVRYDNPAALGTDRLVNALAGWEI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHCCEE
YGRPQGRPVIVVDFGTATKLECVSAEGEYLGGVIAPGIRTAAEALTRRTALLQRVEIQRP
EECCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
KSVIGRNIAASMQSGILYGFAGLADGLVRRLTQEIAPDGPDPVVVATGGLASMVAVESRT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCE
IQMVDPHLTLQGIRLMYELNWPDAAAEA
EEEECCCHHEEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MLLAVDIGNTNITAGLFLEDELICMWRMASNRAETWDEYGLQLIQLLERDGHTPADITCA
CEEEEEECCCCEEEEEEECCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHH
AMASVVPPLNPVLSRAVQQYLKVQLKELTGDLRSLPAVRYDNPAALGTDRLVNALAGWEI
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHCCEE
YGRPQGRPVIVVDFGTATKLECVSAEGEYLGGVIAPGIRTAAEALTRRTALLQRVEIQRP
EECCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
KSVIGRNIAASMQSGILYGFAGLADGLVRRLTQEIAPDGPDPVVVATGGLASMVAVESRT
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCE
IQMVDPHLTLQGIRLMYELNWPDAAAEA
EEEECCCHHEEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA