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The map label for this gene is pucG [H]

Identifier: 51894313

GI number: 51894313

Start: 3385307

End: 3386497

Strand: Reverse

Name: pucG [H]

Synonym: STH3178

Alternate gene names: 51894313

Gene position: 3386497-3385307 (Counterclockwise)

Preceding gene: 51894314

Following gene: 51894311

Centisome position: 94.96

GC content: 69.19

Gene sequence:

>1191_bases
TTGGAGCGCAGGTTCGGAGAGTTGAACCCGCCACAGCGGCTTCTGATGGGGCCAGGCCCTTCCAACGTGGACCCGCGAAT
CCTGAGGGCGATGGCGACGCCGGTCATCGGCCACCTGGATCCGGCGTTCCTGTCGATCATGGATGAGACCATGGGCTGGC
TCCGGGAGGTGTACGAGACCCGGAATCACCACACGGTGCCCATCTCGGCCACGGGCTCGGCCGGCGTCGAGGCGATGATG
GTCAACCTGCTGGAACCCGGGGACGACGTGGTGGTGGGCATTATCGGCTACTTCGGCCAGCGGATGGCGGACGTGGCGTC
CCGCACGGGGGCCAACGTGCGGGTGATCGAGGCGCCCCTGGGCGAGGCGATCCCGCCCGAGCGCTTCGAGGAGGAGCTGC
GGCGCAAGCCTGCGAAGCTGGTCGCCCTGGTGCACGCCGAGACCTCGACCGGGGCGGAGCAGGAGATCGCGCCGGTCGCG
GAGATCGCCCACCGCTACGGCGCCCTGATCGCCATCGACTGCGTGACCTCGCTGGGCGGTATGCCCGTCCGGGTCGACGA
GTGGGGCGTGGACGCGGCGGCGTCCTGTTCGCAGAAGTGCCTGGGCGCCCCGCCCGGGCTGTCGCCGGTCACCTTCAGCC
CCCGGGCGATGGAGGTCATCACCGGCCGCAAGTCCAAGTGCCAGTCATGGTATCTGGACGTGAACCTGCTCTTCGCCTAT
TGGGGTGACGGCAAGGCCAACAACCGGGTGTTCCACCACACCGGGCCGATCACGATGATCTACGCCATGCGGGAGGCGCT
CCGCATCGCCCTGGAGGAGGGGCTGGAGGCCCGCTACGCCCGTCACCGCAAAGCGCACGAGGCGTTCGCCGCCGGCCTGG
AGGCGATGGGGCTCACGCTCTTCACCAAGGGGAAGCGGCTGCCCATGCTCAACGTCATCAACATCCCCGAGGGCATCGAT
GACCTGGCGGTCCGCCGCCGGCTGCTGGAGCAAAACATCGAGATCTCGGGCGGTTTCGGCCCCCTGGCCGGCAGGGTCTG
GCGCGTGGGGCTGATGGGCGTCAACGCCAACCCGGCGCCGGTGATCACCTTGCTAGGCGCCCTGGAGCAGGCCCTGGTGG
AACAGGGGTACCGCTGCGAGCGGGGCGCGGCGGTCGCGGCTGCCCGTGCGGTGTACAAGCAGTCTACTTAG

Upstream 100 bases:

>100_bases
CCCGGTTCCAGGTGCCGGAGAGCGATGACGAGGGGGAGCCCGTCCTGCACTAGCAGGCGGACCTTCTCTACGTGCAGCCA
GTGCCGAGGGGGGAACTGGA

Downstream 100 bases:

>100_bases
GTTGGTGGTGGAAGGCGGCTCTCCGGCTGCGCCGGCGGGGCCGCCTTCCGCGCGCCTGCGGGATGCGGGGTGTGGGCCTC
GCCGGCGGGTGTTACACCAA

Product: class-V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MERRFGELNPPQRLLMGPGPSNVDPRILRAMATPVIGHLDPAFLSIMDETMGWLREVYETRNHHTVPISATGSAGVEAMM
VNLLEPGDDVVVGIIGYFGQRMADVASRTGANVRVIEAPLGEAIPPERFEEELRRKPAKLVALVHAETSTGAEQEIAPVA
EIAHRYGALIAIDCVTSLGGMPVRVDEWGVDAAASCSQKCLGAPPGLSPVTFSPRAMEVITGRKSKCQSWYLDVNLLFAY
WGDGKANNRVFHHTGPITMIYAMREALRIALEEGLEARYARHRKAHEAFAAGLEAMGLTLFTKGKRLPMLNVINIPEGID
DLAVRRRLLEQNIEISGGFGPLAGRVWRVGLMGVNANPAPVITLLGALEQALVEQGYRCERGAAVAAARAVYKQST

Sequences:

>Translated_396_residues
MERRFGELNPPQRLLMGPGPSNVDPRILRAMATPVIGHLDPAFLSIMDETMGWLREVYETRNHHTVPISATGSAGVEAMM
VNLLEPGDDVVVGIIGYFGQRMADVASRTGANVRVIEAPLGEAIPPERFEEELRRKPAKLVALVHAETSTGAEQEIAPVA
EIAHRYGALIAIDCVTSLGGMPVRVDEWGVDAAASCSQKCLGAPPGLSPVTFSPRAMEVITGRKSKCQSWYLDVNLLFAY
WGDGKANNRVFHHTGPITMIYAMREALRIALEEGLEARYARHRKAHEAFAAGLEAMGLTLFTKGKRLPMLNVINIPEGID
DLAVRRRLLEQNIEISGGFGPLAGRVWRVGLMGVNANPAPVITLLGALEQALVEQGYRCERGAAVAAARAVYKQST
>Mature_396_residues
MERRFGELNPPQRLLMGPGPSNVDPRILRAMATPVIGHLDPAFLSIMDETMGWLREVYETRNHHTVPISATGSAGVEAMM
VNLLEPGDDVVVGIIGYFGQRMADVASRTGANVRVIEAPLGEAIPPERFEEELRRKPAKLVALVHAETSTGAEQEIAPVA
EIAHRYGALIAIDCVTSLGGMPVRVDEWGVDAAASCSQKCLGAPPGLSPVTFSPRAMEVITGRKSKCQSWYLDVNLLFAY
WGDGKANNRVFHHTGPITMIYAMREALRIALEEGLEARYARHRKAHEAFAAGLEAMGLTLFTKGKRLPMLNVINIPEGID
DLAVRRRLLEQNIEISGGFGPLAGRVWRVGLMGVNANPAPVITLLGALEQALVEQGYRCERGAAVAAARAVYKQST

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=368, Percent_Identity=39.945652173913, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17536281, Length=368, Percent_Identity=39.1304347826087, Blast_Score=279, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321079, Length=358, Percent_Identity=26.2569832402235, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17530823, Length=369, Percent_Identity=39.5663956639566, Blast_Score=273, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: NA

Molecular weight: Translated: 42975; Mature: 42975

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRFGELNPPQRLLMGPGPSNVDPRILRAMATPVIGHLDPAFLSIMDETMGWLREVYET
CCCCCCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
RNHHTVPISATGSAGVEAMMVNLLEPGDDVVVGIIGYFGQRMADVASRTGANVRVIEAPL
CCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCC
GEAIPPERFEEELRRKPAKLVALVHAETSTGAEQEIAPVAEIAHRYGALIAIDCVTSLGG
CCCCCHHHHHHHHHHCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHCCC
MPVRVDEWGVDAAASCSQKCLGAPPGLSPVTFSPRAMEVITGRKSKCQSWYLDVNLLFAY
CEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHEEEEEEEEEEEE
WGDGKANNRVFHHTGPITMIYAMREALRIALEEGLEARYARHRKAHEAFAAGLEAMGLTL
ECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
FTKGKRLPMLNVINIPEGIDDLAVRRRLLEQNIEISGGFGPLAGRVWRVGLMGVNANPAP
EECCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEECCCCCHHHHHEEEEEEEECCCCCHH
VITLLGALEQALVEQGYRCERGAAVAAARAVYKQST
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MERRFGELNPPQRLLMGPGPSNVDPRILRAMATPVIGHLDPAFLSIMDETMGWLREVYET
CCCCCCCCCCCHHEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
RNHHTVPISATGSAGVEAMMVNLLEPGDDVVVGIIGYFGQRMADVASRTGANVRVIEAPL
CCCEEEEEECCCCCCHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEECCC
GEAIPPERFEEELRRKPAKLVALVHAETSTGAEQEIAPVAEIAHRYGALIAIDCVTSLGG
CCCCCHHHHHHHHHHCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHCCEEEEEHHHHCCC
MPVRVDEWGVDAAASCSQKCLGAPPGLSPVTFSPRAMEVITGRKSKCQSWYLDVNLLFAY
CEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCHHHHEEEEEEEEEEEE
WGDGKANNRVFHHTGPITMIYAMREALRIALEEGLEARYARHRKAHEAFAAGLEAMGLTL
ECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEE
FTKGKRLPMLNVINIPEGIDDLAVRRRLLEQNIEISGGFGPLAGRVWRVGLMGVNANPAP
EECCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEECCCCCHHHHHEEEEEEEECCCCCHH
VITLLGALEQALVEQGYRCERGAAVAAARAVYKQST
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]