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The map label for this gene is kstR2 [H]

Identifier: 51893625

GI number: 51893625

Start: 2669181

End: 2669852

Strand: Reverse

Name: kstR2 [H]

Synonym: STH2487

Alternate gene names: 51893625

Gene position: 2669852-2669181 (Counterclockwise)

Preceding gene: 51893627

Following gene: 51893624

Centisome position: 74.87

GC content: 73.36

Gene sequence:

>672_bases
ATGGGCCGAAACCGGCGCAGGGAGGCCATGCTGCAGGCCGCCATCGGCCTGTTCAGCGACAAGGGGTACCACGCCACCAC
CGTACGGGAGATCGCCCAGGCGGTGGGGATCCTCCCCGGGTCGCTGTACGCGCACATGGCCTCCAAGGAGGACCTGCTCT
ACGAGGCGGTGGTGCAGGCGTCGGAACGCTTCCAGGAGGCGGTCGCGCCGATTGCGGAGTCCCCCGGACACGCCGGAGAG
CGGCTCCGGCAGGCGATGGCGGCGCACATCCGGGTCGTCGCCGAGTCGCCGGCCGCGGCCACCGTCTTCCTGCACGAGTG
GCGGGCTCTGTCTCCCCAGCGGCGGGCGATGGCGGTGGCCCACCGCCGGGCGTACGAGGAGCTCCTGGCCCGCATCATCC
GCGAGGGGGTCGAGTCCGGCGTCTTCCGGCCCGTTGACGAGAAGTTTGTCCGGCTGCTGGTCCTGAGCGCGGTGAACTGG
ACGTACCAGTGGTACCGCGCCGACGGCCCGCTCAGCCCCGAGCAGGTCGCGGACCAGTTCTACGCCATCATCGCCGGGGG
GCTGCTGCGCAACGCGGCGGATCCGGGGAGCGCGGCCCTGCCGGCGAGCGCCGATGGGGAGCCCGCGCCGCAGGGCCCTT
CGCGCGTGGCCGCGGGCGGGGAGAGCGGGTAG

Upstream 100 bases:

>100_bases
CTCCCCGCCGGCGCAGCATGCCGGGCGGTCCGGCGCTTGACGGGTTGCGAAGAGGGAGAATATACTGATAACCAATCAAG
CGCTTGCTAGGAGGGATGGA

Downstream 100 bases:

>100_bases
GTCCCCCTCCAACTGTGGGCGCCTGAACCGCTGCGGATCAAGCCCGCCGCCCATCGCCCCACATCGATTGTCATCTTCAC
GGCCGCAACGGGGAGGGAGA

Product: TetR/AcrR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MGRNRRREAMLQAAIGLFSDKGYHATTVREIAQAVGILPGSLYAHMASKEDLLYEAVVQASERFQEAVAPIAESPGHAGE
RLRQAMAAHIRVVAESPAAATVFLHEWRALSPQRRAMAVAHRRAYEELLARIIREGVESGVFRPVDEKFVRLLVLSAVNW
TYQWYRADGPLSPEQVADQFYAIIAGGLLRNAADPGSAALPASADGEPAPQGPSRVAAGGESG

Sequences:

>Translated_223_residues
MGRNRRREAMLQAAIGLFSDKGYHATTVREIAQAVGILPGSLYAHMASKEDLLYEAVVQASERFQEAVAPIAESPGHAGE
RLRQAMAAHIRVVAESPAAATVFLHEWRALSPQRRAMAVAHRRAYEELLARIIREGVESGVFRPVDEKFVRLLVLSAVNW
TYQWYRADGPLSPEQVADQFYAIIAGGLLRNAADPGSAALPASADGEPAPQGPSRVAAGGESG
>Mature_222_residues
GRNRRREAMLQAAIGLFSDKGYHATTVREIAQAVGILPGSLYAHMASKEDLLYEAVVQASERFQEAVAPIAESPGHAGER
LRQAMAAHIRVVAESPAAATVFLHEWRALSPQRRAMAVAHRRAYEELLARIIREGVESGVFRPVDEKFVRLLVLSAVNWT
YQWYRADGPLSPEQVADQFYAIIAGGLLRNAADPGSAALPASADGEPAPQGPSRVAAGGESG

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 24067; Mature: 23935

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRNRRREAMLQAAIGLFSDKGYHATTVREIAQAVGILPGSLYAHMASKEDLLYEAVVQA
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SERFQEAVAPIAESPGHAGERLRQAMAAHIRVVAESPAAATVFLHEWRALSPQRRAMAVA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHH
HRRAYEELLARIIREGVESGVFRPVDEKFVRLLVLSAVNWTYQWYRADGPLSPEQVADQF
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHH
YAIIAGGLLRNAADPGSAALPASADGEPAPQGPSRVAAGGESG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GRNRRREAMLQAAIGLFSDKGYHATTVREIAQAVGILPGSLYAHMASKEDLLYEAVVQA
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
SERFQEAVAPIAESPGHAGERLRQAMAAHIRVVAESPAAATVFLHEWRALSPQRRAMAVA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHH
HRRAYEELLARIIREGVESGVFRPVDEKFVRLLVLSAVNWTYQWYRADGPLSPEQVADQF
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHH
YAIIAGGLLRNAADPGSAALPASADGEPAPQGPSRVAAGGESG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]