Click here to switch to the map view.

The map label for this gene is hflK [H]

Identifier: 51893115

GI number: 51893115

Start: 2114205

End: 2115044

Strand: Reverse

Name: hflK [H]

Synonym: STH1977

Alternate gene names: 51893115

Gene position: 2115044-2114205 (Counterclockwise)

Preceding gene: 51893118

Following gene: 51893114

Centisome position: 59.31

GC content: 67.5

Gene sequence:

>840_bases
GTGGAAGAGCACGAGTCGGCGCTGGTGCTCACGATGGGGCGAGCCACCCGCCAGGTGGACAAGGGCGTGCATACCAAGCT
GCCCTGGCCGTTGGAGACGGCGGTGGTGTTGCCGACCAAGCAGACCCAGGAGCTGCAGTTCGGCTTCCGGGAACAGAACG
GCCGGGTCCAGCTGGTGGAGGACGAGGCGCTGATGATCACCGGCGACGAGAACCTGGTGTGGGCCGATCTCCTGGTGGAG
TGGCGCATCCAGGACATCGAGAAGTACCTCTTCGCCGTGGACGACCCCGATCGGCTGCTCCGCAACGCCACCGCGGCCGC
CCTGCGCTCGGTGATGGGCACCACGGGCCTGGACTTCGCCATCACCACGGGCAAGTTCGAGATCCAGGAGGAGGTGGAGC
GGCAGCTGGTGGAGCTCATGGACTCCTACGGCGCCGGCATCATGATCATCGACGTCAAGCTGCAGGACGTGGAGCCGCCG
CAGCAGGTCTCCGCCGAGTTCAAGGCGGTGACCGACGCCCGGGAGGCCCAGCAGACCAAGATCAACGAGGCCGGCAAGTA
CGAGGCCGAGCGGATCCCCGCGGCCCGGGCCGAGGCCCAGAAGCTGCTGGAGCAGGCCGAGGCCAACAAGCAGGCCCGCA
TCAACCAGGCCCTGGCTGAGGTGGCCCAGTACAAGGCCATCTACGAGGCGTACAAGGCCAACCCGGACGTGACCCGGGAG
CGGCTCCTGCTGGAGACCCTGGAGCAGATCCTGCCCGGGGCGGACATCGTCATCGTGGATTCCAGCGAGGGCACGGTGAA
GTACCTGCCCATCGTGCCGGGAGGGGGTGGCAGCCAGTGA

Upstream 100 bases:

>100_bases
CAAAAGGAGGTTGGAGCGAGTGCGACTGATCCGGCGCGCGCTGCTGGGGCTCCTGCTGACGGCTCTGGCGGCGAACCTGG
CCCTGACGACCTGGTTCCGG

Downstream 100 bases:

>100_bases
CGCCGGAGCGTGAGCCCATCGATCTGAAGATCCAGGTGAACCCGGGCGAGGTGAAGCGGCTGCTGGCGTGGATCGTCGCC
ATCGCCGTGATCGCCGGGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MEEHESALVLTMGRATRQVDKGVHTKLPWPLETAVVLPTKQTQELQFGFREQNGRVQLVEDEALMITGDENLVWADLLVE
WRIQDIEKYLFAVDDPDRLLRNATAAALRSVMGTTGLDFAITTGKFEIQEEVERQLVELMDSYGAGIMIIDVKLQDVEPP
QQVSAEFKAVTDAREAQQTKINEAGKYEAERIPAARAEAQKLLEQAEANKQARINQALAEVAQYKAIYEAYKANPDVTRE
RLLLETLEQILPGADIVIVDSSEGTVKYLPIVPGGGGSQ

Sequences:

>Translated_279_residues
MEEHESALVLTMGRATRQVDKGVHTKLPWPLETAVVLPTKQTQELQFGFREQNGRVQLVEDEALMITGDENLVWADLLVE
WRIQDIEKYLFAVDDPDRLLRNATAAALRSVMGTTGLDFAITTGKFEIQEEVERQLVELMDSYGAGIMIIDVKLQDVEPP
QQVSAEFKAVTDAREAQQTKINEAGKYEAERIPAARAEAQKLLEQAEANKQARINQALAEVAQYKAIYEAYKANPDVTRE
RLLLETLEQILPGADIVIVDSSEGTVKYLPIVPGGGGSQ
>Mature_279_residues
MEEHESALVLTMGRATRQVDKGVHTKLPWPLETAVVLPTKQTQELQFGFREQNGRVQLVEDEALMITGDENLVWADLLVE
WRIQDIEKYLFAVDDPDRLLRNATAAALRSVMGTTGLDFAITTGKFEIQEEVERQLVELMDSYGAGIMIIDVKLQDVEPP
QQVSAEFKAVTDAREAQQTKINEAGKYEAERIPAARAEAQKLLEQAEANKQARINQALAEVAQYKAIYEAYKANPDVTRE
RLLLETLEQILPGADIVIVDSSEGTVKYLPIVPGGGGSQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=209, Percent_Identity=39.7129186602871, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 31035; Mature: 31035

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEHESALVLTMGRATRQVDKGVHTKLPWPLETAVVLPTKQTQELQFGFREQNGRVQLVE
CCCCCCEEEEEECHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHCCEECCCCCEEEEE
DEALMITGDENLVWADLLVEWRIQDIEKYLFAVDDPDRLLRNATAAALRSVMGTTGLDFA
CCEEEEECCCCEEEHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCCEE
ITTGKFEIQEEVERQLVELMDSYGAGIMIIDVKLQDVEPPQQVSAEFKAVTDAREAQQTK
EECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
INEAGKYEAERIPAARAEAQKLLEQAEANKQARINQALAEVAQYKAIYEAYKANPDVTRE
HHCCCCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RLLLETLEQILPGADIVIVDSSEGTVKYLPIVPGGGGSQ
HHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MEEHESALVLTMGRATRQVDKGVHTKLPWPLETAVVLPTKQTQELQFGFREQNGRVQLVE
CCCCCCEEEEEECHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHCCEECCCCCEEEEE
DEALMITGDENLVWADLLVEWRIQDIEKYLFAVDDPDRLLRNATAAALRSVMGTTGLDFA
CCEEEEECCCCEEEHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCCCCEE
ITTGKFEIQEEVERQLVELMDSYGAGIMIIDVKLQDVEPPQQVSAEFKAVTDAREAQQTK
EECCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
INEAGKYEAERIPAARAEAQKLLEQAEANKQARINQALAEVAQYKAIYEAYKANPDVTRE
HHCCCCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RLLLETLEQILPGADIVIVDSSEGTVKYLPIVPGGGGSQ
HHHHHHHHHHCCCCCEEEEECCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]