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The map label for this gene is hflC [H]

Identifier: 51893114

GI number: 51893114

Start: 2113294

End: 2114208

Strand: Reverse

Name: hflC [H]

Synonym: STH1976

Alternate gene names: 51893114

Gene position: 2114208-2113294 (Counterclockwise)

Preceding gene: 51893115

Following gene: 51893106

Centisome position: 59.29

GC content: 67.54

Gene sequence:

>915_bases
GTGACGCCGGAGCGTGAGCCCATCGATCTGAAGATCCAGGTGAACCCGGGCGAGGTGAAGCGGCTGCTGGCGTGGATCGT
CGCCATCGCCGTGATCGCCGGGGCGCTCAGCCAGGTGATCTTCGTCCGGGAGGACGAGTACCTGGTGATCCGTTCCTGGA
CCGGCGTGGTGCAGCGGGTGGTGACCGAAGCGGGGCCGACCTTCAAGATCCCCCTGCTCCAGTCGGCGCAGACCCTGCCC
AAGCATCGCGTGGTGCACGACAGCAACCCGGCGGAGCTGCTCACCGCCGACCAGAAGCCCATCATTGTGGACCACTACAC
TGTCTGGCAGATCACCGACCCGCGCCTCTTCGTGCAGAACACCCAGACCGTGGCGCGGGCGGAGCAGCGCATCGACGCGG
CCGTCTACTCCACCGTCCGGGGCGTGCTGGGCCGGCTGAAGTTCGGCGAGATCATCTCGGAGGGCGAGTCGGCCCGGGGC
AACCTGAACCAGGAGGTCACCCGGCTGGTCAACGAGCAGCTGGCCAGCTACGGCATCACCGTCCACGACGTGCGGCTGAA
GCGGACCGACCTGCCCCCGCAGAATCTGGAGTCCGTGTTCAACCGCATGAAGTCGGAGCGGTCCAAGATCGCCCAGGACT
ACCTGTCGCAGGGCGACGAGCAGGCGGCCATCATCCGGGCCCGCACCGACAAGGAGGCGACCCTGATCGTCTCCGAGGCG
GCCCGGAAGGCGGCCGAGATCGAGGCCGAGGGCGAGGCGGAGGCCGCGCGCATCTTCAACGAGGCGTACGGCGCCGACCC
TGAGTTCTACGCCTTCTACCGCACGCTGGAGTCCTACAAGACCACCCTGAACGGCAAGCCGACGATCGTCATCCCCATCG
ACTCGCCGTACGCCCGGCTGCTGATGGGCCAGTGA

Upstream 100 bases:

>100_bases
CCCTGGAGCAGATCCTGCCCGGGGCGGACATCGTCATCGTGGATTCCAGCGAGGGCACGGTGAAGTACCTGCCCATCGTG
CCGGGAGGGGGTGGCAGCCA

Downstream 100 bases:

>100_bases
GAGTCAGTCCGTGTGCGGTCTGCGACATCGCGAAGTGCGGCGCCCTGCTGGGCGCCGCACTTCGCTATGGGCTGCCGGCC
TGCACCGGCCGGTCGGTGTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTPEREPIDLKIQVNPGEVKRLLAWIVAIAVIAGALSQVIFVREDEYLVIRSWTGVVQRVVTEAGPTFKIPLLQSAQTLP
KHRVVHDSNPAELLTADQKPIIVDHYTVWQITDPRLFVQNTQTVARAEQRIDAAVYSTVRGVLGRLKFGEIISEGESARG
NLNQEVTRLVNEQLASYGITVHDVRLKRTDLPPQNLESVFNRMKSERSKIAQDYLSQGDEQAAIIRARTDKEATLIVSEA
ARKAAEIEAEGEAEAARIFNEAYGADPEFYAFYRTLESYKTTLNGKPTIVIPIDSPYARLLMGQ

Sequences:

>Translated_304_residues
MTPEREPIDLKIQVNPGEVKRLLAWIVAIAVIAGALSQVIFVREDEYLVIRSWTGVVQRVVTEAGPTFKIPLLQSAQTLP
KHRVVHDSNPAELLTADQKPIIVDHYTVWQITDPRLFVQNTQTVARAEQRIDAAVYSTVRGVLGRLKFGEIISEGESARG
NLNQEVTRLVNEQLASYGITVHDVRLKRTDLPPQNLESVFNRMKSERSKIAQDYLSQGDEQAAIIRARTDKEATLIVSEA
ARKAAEIEAEGEAEAARIFNEAYGADPEFYAFYRTLESYKTTLNGKPTIVIPIDSPYARLLMGQ
>Mature_303_residues
TPEREPIDLKIQVNPGEVKRLLAWIVAIAVIAGALSQVIFVREDEYLVIRSWTGVVQRVVTEAGPTFKIPLLQSAQTLPK
HRVVHDSNPAELLTADQKPIIVDHYTVWQITDPRLFVQNTQTVARAEQRIDAAVYSTVRGVLGRLKFGEIISEGESARGN
LNQEVTRLVNEQLASYGITVHDVRLKRTDLPPQNLESVFNRMKSERSKIAQDYLSQGDEQAAIIRARTDKEATLIVSEAA
RKAAEIEAEGEAEAARIFNEAYGADPEFYAFYRTLESYKTTLNGKPTIVIPIDSPYARLLMGQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=284, Percent_Identity=29.5774647887324, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786697, Length=233, Percent_Identity=25.3218884120172, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 34011; Mature: 33880

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEREPIDLKIQVNPGEVKRLLAWIVAIAVIAGALSQVIFVREDEYLVIRSWTGVVQRV
CCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECHHHHHHHH
VTEAGPTFKIPLLQSAQTLPKHRVVHDSNPAELLTADQKPIIVDHYTVWQITDPRLFVQN
HHHCCCEEEEHHHHHHHHCCCCCCCCCCCCHHEEECCCCCEEEEEEEEEEEECCEEEEEC
TQTVARAEQRIDAAVYSTVRGVLGRLKFGEIISEGESARGNLNQEVTRLVNEQLASYGIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCE
VHDVRLKRTDLPPQNLESVFNRMKSERSKIAQDYLSQGDEQAAIIRARTDKEATLIVSEA
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEHHHH
ARKAAEIEAEGEAEAARIFNEAYGADPEFYAFYRTLESYKTTLNGKPTIVIPIDSPYARL
HHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
LMGQ
HCCC
>Mature Secondary Structure 
TPEREPIDLKIQVNPGEVKRLLAWIVAIAVIAGALSQVIFVREDEYLVIRSWTGVVQRV
CCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEECHHHHHHHH
VTEAGPTFKIPLLQSAQTLPKHRVVHDSNPAELLTADQKPIIVDHYTVWQITDPRLFVQN
HHHCCCEEEEHHHHHHHHCCCCCCCCCCCCHHEEECCCCCEEEEEEEEEEEECCEEEEEC
TQTVARAEQRIDAAVYSTVRGVLGRLKFGEIISEGESARGNLNQEVTRLVNEQLASYGIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCE
VHDVRLKRTDLPPQNLESVFNRMKSERSKIAQDYLSQGDEQAAIIRARTDKEATLIVSEA
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEHHHH
ARKAAEIEAEGEAEAARIFNEAYGADPEFYAFYRTLESYKTTLNGKPTIVIPIDSPYARL
HHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
LMGQ
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]