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The map label for this gene is lytR [H]

Identifier: 51893021

GI number: 51893021

Start: 2023596

End: 2025059

Strand: Reverse

Name: lytR [H]

Synonym: STH1883

Alternate gene names: 51893021

Gene position: 2025059-2023596 (Counterclockwise)

Preceding gene: 51893022

Following gene: 51893020

Centisome position: 56.79

GC content: 69.74

Gene sequence:

>1464_bases
GTGCGCTCAACATCAAAGAAGTCCACACGCAAGCGGTGGCACTGGGTGATCCCTCTGGTGCTTCTTCTCGCCCTCGCAGC
CGCAGTCCGCGCCGTGGCGCTTCACCGACCGTTTGACTCGCCGGCGACCGCCGATCCGGGCAGGTCCAATCCCACGAACC
CGGACGGCTCGGCGGAGGAACAGCCCCCGCTGCACACGCTGCCGGAGCTGCAGACCTTCCTCGTGATGGGCGTGGACAGC
ATGGAGGGAGAGTGGGGCCGATCGGACTCGCTGATGGTCGTCTCGTACAACCCCCGTGAACAGCGGGTCGCCATGCTCTC
CATTCCCCGTGACCTCTGGACGTACATCCCCGGCCGCGGGTACGACAAGATCAACCACGCCTACGCCTTCGGAGGCCCCA
CCCTGTCGGTGGAGACGGTGGAGCGGTTGTTGGGCATGGACATCGACCATTGGGTTTCCATCTCCTTCGACGGGTTCGTT
GAGGTCATCGACGCCCTGGGCGGCGTGGAGGTGAACCCGCCCGAGCCGCTCTACTACGTCGATCCCGCAGACCGGCGCTT
CGGCCCGGAGGGGCTGGTGATCGACATTCAGGCCGGGCCGCAGGTGATGGACGGCCTCACCGCGCTGAAGTACGCCCGGT
TCCGGTCGGACTCCCAGGGCGACGTGGGCCGCATGCGGCGCCAGCAGGAGATCATCCAGGCCGCCATGAAGAAGGCGGCG
TCCCCGGCCCTGTTCGCCCGGGCCGGCCAGCTGATCCCGGCCCTGTACCACACCATCGGCACCGACATGACGGTGGGGGA
GATGCTGAAGCTGGCCACCACCGGGCGCCAGGCCCTGACCAAGTCCCCGGTCACGGGCACCATCGAGGCGGACGAGTACT
GGATCGACGGCGTCTTCTACTTCGGCGCCGATCTGGTGAAGCTGCGGTCCACGGCCTACGAGCTCCTGGTGGGCGAGCCG
CCCGGCGAGGACTTCCTCGCCCGGGCGCAGGCCGACAACCAGGAGTACCAGTCCGTGCTGCAGCGGGAGGTGGCCCGCTC
TCAGGCGGCCGCAGCCGCCCGGGCCGAGGAGGAGGCCGCCAACAGCGACGGGGAAAGCGGGGAGACCGTGGCGGATCCGA
CCGGTGACGGCCTGGGCGGCGACGCCGCGGAAGGCCCGGACGGGACCGCCGACGAGACGGCCGGTGCCTGGGCCTCGGTC
TACGTGGTGGACGCCACGGGCCAGGGGGCTGCGTGGGATTACGTGGCCGGCCTGGAGGCCGCCGGAATGCGGGTGCGGGT
CCACGAGAGCCAGGCGGTGCTCTCCGTGACGATGGCACTGGTGCGCGACCCGGAGCTGGACGAGGAAAGCGTGCGGCAGC
GCCTGGAGAGCGTGATTCCCGGCGTCGTGATCCGGATGGCCCCGGACCCGACCGCCGCCGATGACATCGACCTGGTGCTG
GGCACCAACGTGCTGGGCGACTGA

Upstream 100 bases:

>100_bases
CGTCAAACTACGGTAGGTCCCTCATGAAGATCCCTATCCGATAACGTTCTTTTCTCTGCTATAGTAAGACAGGTAAACTC
CGCAACGAGGAGGGTGGCCC

Downstream 100 bases:

>100_bases
ACAACTTGGCGCACATGGCGGACCAGGGCGCTGGCCCTGGTCTTCGTGTTGACAGGGGCGGTGCGGGCGGCTAAACTCAA
ATAGGAATTTTACTGGTTCG

Product: LytR family transcriptional regulator

Products: NA

Alternate protein names: Membrane-bound protein lytR [H]

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MRSTSKKSTRKRWHWVIPLVLLLALAAAVRAVALHRPFDSPATADPGRSNPTNPDGSAEEQPPLHTLPELQTFLVMGVDS
MEGEWGRSDSLMVVSYNPREQRVAMLSIPRDLWTYIPGRGYDKINHAYAFGGPTLSVETVERLLGMDIDHWVSISFDGFV
EVIDALGGVEVNPPEPLYYVDPADRRFGPEGLVIDIQAGPQVMDGLTALKYARFRSDSQGDVGRMRRQQEIIQAAMKKAA
SPALFARAGQLIPALYHTIGTDMTVGEMLKLATTGRQALTKSPVTGTIEADEYWIDGVFYFGADLVKLRSTAYELLVGEP
PGEDFLARAQADNQEYQSVLQREVARSQAAAAARAEEEAANSDGESGETVADPTGDGLGGDAAEGPDGTADETAGAWASV
YVVDATGQGAAWDYVAGLEAAGMRVRVHESQAVLSVTMALVRDPELDEESVRQRLESVIPGVVIRMAPDPTAADDIDLVL
GTNVLGD

Sequences:

>Translated_487_residues
MRSTSKKSTRKRWHWVIPLVLLLALAAAVRAVALHRPFDSPATADPGRSNPTNPDGSAEEQPPLHTLPELQTFLVMGVDS
MEGEWGRSDSLMVVSYNPREQRVAMLSIPRDLWTYIPGRGYDKINHAYAFGGPTLSVETVERLLGMDIDHWVSISFDGFV
EVIDALGGVEVNPPEPLYYVDPADRRFGPEGLVIDIQAGPQVMDGLTALKYARFRSDSQGDVGRMRRQQEIIQAAMKKAA
SPALFARAGQLIPALYHTIGTDMTVGEMLKLATTGRQALTKSPVTGTIEADEYWIDGVFYFGADLVKLRSTAYELLVGEP
PGEDFLARAQADNQEYQSVLQREVARSQAAAAARAEEEAANSDGESGETVADPTGDGLGGDAAEGPDGTADETAGAWASV
YVVDATGQGAAWDYVAGLEAAGMRVRVHESQAVLSVTMALVRDPELDEESVRQRLESVIPGVVIRMAPDPTAADDIDLVL
GTNVLGD
>Mature_487_residues
MRSTSKKSTRKRWHWVIPLVLLLALAAAVRAVALHRPFDSPATADPGRSNPTNPDGSAEEQPPLHTLPELQTFLVMGVDS
MEGEWGRSDSLMVVSYNPREQRVAMLSIPRDLWTYIPGRGYDKINHAYAFGGPTLSVETVERLLGMDIDHWVSISFDGFV
EVIDALGGVEVNPPEPLYYVDPADRRFGPEGLVIDIQAGPQVMDGLTALKYARFRSDSQGDVGRMRRQQEIIQAAMKKAA
SPALFARAGQLIPALYHTIGTDMTVGEMLKLATTGRQALTKSPVTGTIEADEYWIDGVFYFGADLVKLRSTAYELLVGEP
PGEDFLARAQADNQEYQSVLQREVARSQAAAAARAEEEAANSDGESGETVADPTGDGLGGDAAEGPDGTADETAGAWASV
YVVDATGQGAAWDYVAGLEAAGMRVRVHESQAVLSVTMALVRDPELDEESVRQRLESVIPGVVIRMAPDPTAADDIDLVL
GTNVLGD

Specific function: Attenuator role for operon expression [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 52507; Mature: 52507

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTSKKSTRKRWHWVIPLVLLLALAAAVRAVALHRPFDSPATADPGRSNPTNPDGSAEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
QPPLHTLPELQTFLVMGVDSMEGEWGRSDSLMVVSYNPREQRVAMLSIPRDLWTYIPGRG
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHEEEEEECCHHHHHHCCCCC
YDKINHAYAFGGPTLSVETVERLLGMDIDHWVSISFDGFVEVIDALGGVEVNPPEPLYYV
CCCCCCEEECCCCEEEHHHHHHHHCCCHHHEEEECHHHHHHHHHHHCCEECCCCCCEEEE
DPADRRFGPEGLVIDIQAGPQVMDGLTALKYARFRSDSQGDVGRMRRQQEIIQAAMKKAA
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
SPALFARAGQLIPALYHTIGTDMTVGEMLKLATTGRQALTKSPVTGTIEADEYWIDGVFY
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCCCCEEEECCCEEECCHHH
FGADLVKLRSTAYELLVGEPPGEDFLARAQADNQEYQSVLQREVARSQAAAAARAEEEAA
HHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NSDGESGETVADPTGDGLGGDAAEGPDGTADETAGAWASVYVVDATGQGAAWDYVAGLEA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHH
AGMRVRVHESQAVLSVTMALVRDPELDEESVRQRLESVIPGVVIRMAPDPTAADDIDLVL
CCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEE
GTNVLGD
CCCCCCC
>Mature Secondary Structure
MRSTSKKSTRKRWHWVIPLVLLLALAAAVRAVALHRPFDSPATADPGRSNPTNPDGSAEE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
QPPLHTLPELQTFLVMGVDSMEGEWGRSDSLMVVSYNPREQRVAMLSIPRDLWTYIPGRG
CCCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHEEEEEECCHHHHHHCCCCC
YDKINHAYAFGGPTLSVETVERLLGMDIDHWVSISFDGFVEVIDALGGVEVNPPEPLYYV
CCCCCCEEECCCCEEEHHHHHHHHCCCHHHEEEECHHHHHHHHHHHCCEECCCCCCEEEE
DPADRRFGPEGLVIDIQAGPQVMDGLTALKYARFRSDSQGDVGRMRRQQEIIQAAMKKAA
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
SPALFARAGQLIPALYHTIGTDMTVGEMLKLATTGRQALTKSPVTGTIEADEYWIDGVFY
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHCCCCCEEEECCCEEECCHHH
FGADLVKLRSTAYELLVGEPPGEDFLARAQADNQEYQSVLQREVARSQAAAAARAEEEAA
HHHHHHHHHHHHHHEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NSDGESGETVADPTGDGLGGDAAEGPDGTADETAGAWASVYVVDATGQGAAWDYVAGLEA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHH
AGMRVRVHESQAVLSVTMALVRDPELDEESVRQRLESVIPGVVIRMAPDPTAADDIDLVL
CCEEEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEE
GTNVLGD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]