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The map label for this gene is xerD [H]

Identifier: 51892959

GI number: 51892959

Start: 1965866

End: 1966750

Strand: Reverse

Name: xerD [H]

Synonym: STH1821

Alternate gene names: 51892959

Gene position: 1966750-1965866 (Counterclockwise)

Preceding gene: 51892960

Following gene: 51892958

Centisome position: 55.15

GC content: 64.07

Gene sequence:

>885_bases
ATGAACAACTTGATCCATGAGTTCATCAACTACCTGAGCGTGGAAAGGGGCCTGGCGACCAACACCCTGGAGTCGTACGG
CCGCGACCTGCGCCAGTACTACCAGTATCTCGGGGAGGATCAAGTCGACCTCGACGCCGTCTCTCGCTCGACCATCATTA
ATTACCTGATGTACCTGCAGAAGCAGGGGAAGGCGACCGCGACCATCGCCCGGCGGCTGGCGGCGCTGAAGGCCTTCTAC
CAGTTCCTTGTCAGGGAGAAACGCATCAAGACCGACCCCACCGCCAACCTGGAGTCGCCGAAGCTGGAGAAACGGCTGCC
GCGGGTGCTCACCGTCAGTGAGGTGGAGCGGCTGCTCGCCCAGCCGGACCCGTCGCTGCCCGCAGGCCTCCGGGACCGGG
CGATGCTGGAGCTGCTGTACGCCACCGGCATCCGGGTGTCGGAGCTGGTCTCGCTGAACATAGAGGACGTCAACTTGGAG
ACGGGCTACATACGCTGCACCGGCAAGGGGTCGAAGGAGCGGATCGTGCCGCTGGGCAGCCTGGCGATCAAGTGGGTGAA
GGAGTACCTGCAGCAGGGCCGGCCGAAGCTGGTGAAGGACCGGGAAGAGGCCGCTCTCTTCGTCAACCACCACGGGCACC
GGCTGACCCGCCAGGGCTTCTGGAAGATCGTCAAGAAGTACGCCGAGGACGCCCGCATCGACAAGGAGATCACCCCGCAT
ACCCTGCGCCACTCCTTCGCCACCCACCTGCTCGAGAACGGCGCCGACCTGCGGTCGGTTCAGGAGATGCTGGGCCACGC
CGACATCTCGACGACGCAGATCTATACACACGTCACCAAGGGCCGGCTGAAAGAGGTCTACGCGCGGACCCATCCCCGGG
CATAG

Upstream 100 bases:

>100_bases
CTGAATTCCGTGGAATTGACAAAATCGGTCAGGTCTGACGCATAATCCGCCCCGATATGCGAGAGAATGATTACCACTAA
TGGCGCGAAGGGGATGCAAC

Downstream 100 bases:

>100_bases
GCGGCGACGCGCACACGTCCGCGGGCCTGCCGAGCGCAGGCCCGCTTTTCCCTGCCCTGTTCCAGTGCTATAGTGAGAGA
CGAAGTCCAGACAAAGGAGT

Product: recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MNNLIHEFINYLSVERGLATNTLESYGRDLRQYYQYLGEDQVDLDAVSRSTIINYLMYLQKQGKATATIARRLAALKAFY
QFLVREKRIKTDPTANLESPKLEKRLPRVLTVSEVERLLAQPDPSLPAGLRDRAMLELLYATGIRVSELVSLNIEDVNLE
TGYIRCTGKGSKERIVPLGSLAIKWVKEYLQQGRPKLVKDREEAALFVNHHGHRLTRQGFWKIVKKYAEDARIDKEITPH
TLRHSFATHLLENGADLRSVQEMLGHADISTTQIYTHVTKGRLKEVYARTHPRA

Sequences:

>Translated_294_residues
MNNLIHEFINYLSVERGLATNTLESYGRDLRQYYQYLGEDQVDLDAVSRSTIINYLMYLQKQGKATATIARRLAALKAFY
QFLVREKRIKTDPTANLESPKLEKRLPRVLTVSEVERLLAQPDPSLPAGLRDRAMLELLYATGIRVSELVSLNIEDVNLE
TGYIRCTGKGSKERIVPLGSLAIKWVKEYLQQGRPKLVKDREEAALFVNHHGHRLTRQGFWKIVKKYAEDARIDKEITPH
TLRHSFATHLLENGADLRSVQEMLGHADISTTQIYTHVTKGRLKEVYARTHPRA
>Mature_294_residues
MNNLIHEFINYLSVERGLATNTLESYGRDLRQYYQYLGEDQVDLDAVSRSTIINYLMYLQKQGKATATIARRLAALKAFY
QFLVREKRIKTDPTANLESPKLEKRLPRVLTVSEVERLLAQPDPSLPAGLRDRAMLELLYATGIRVSELVSLNIEDVNLE
TGYIRCTGKGSKERIVPLGSLAIKWVKEYLQQGRPKLVKDREEAALFVNHHGHRLTRQGFWKIVKKYAEDARIDKEITPH
TLRHSFATHLLENGADLRSVQEMLGHADISTTQIYTHVTKGRLKEVYARTHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=48.4641638225256, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1790244, Length=291, Percent_Identity=38.4879725085911, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI1790768, Length=185, Percent_Identity=31.3513513513514, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790767, Length=197, Percent_Identity=30.9644670050761, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33724; Mature: 33724

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLIHEFINYLSVERGLATNTLESYGRDLRQYYQYLGEDQVDLDAVSRSTIINYLMYLQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KQGKATATIARRLAALKAFYQFLVREKRIKTDPTANLESPKLEKRLPRVLTVSEVERLLA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHCCHHHHHHHHH
QPDPSLPAGLRDRAMLELLYATGIRVSELVSLNIEDVNLETGYIRCTGKGSKERIVPLGS
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCHHH
LAIKWVKEYLQQGRPKLVKDREEAALFVNHHGHRLTRQGFWKIVKKYAEDARIDKEITPH
HHHHHHHHHHHCCCCCHHCCHHHHEEEHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
TLRHSFATHLLENGADLRSVQEMLGHADISTTQIYTHVTKGRLKEVYARTHPRA
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNNLIHEFINYLSVERGLATNTLESYGRDLRQYYQYLGEDQVDLDAVSRSTIINYLMYLQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KQGKATATIARRLAALKAFYQFLVREKRIKTDPTANLESPKLEKRLPRVLTVSEVERLLA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHCCHHHHHHHHH
QPDPSLPAGLRDRAMLELLYATGIRVSELVSLNIEDVNLETGYIRCTGKGSKERIVPLGS
CCCCCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCEEEEECCCEEEEECCCCCCCCCCHHH
LAIKWVKEYLQQGRPKLVKDREEAALFVNHHGHRLTRQGFWKIVKKYAEDARIDKEITPH
HHHHHHHHHHHCCCCCHHCCHHHHEEEHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHH
TLRHSFATHLLENGADLRSVQEMLGHADISTTQIYTHVTKGRLKEVYARTHPRA
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]