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The map label for this gene is phoB [H]

Identifier: 51891982

GI number: 51891982

Start: 955427

End: 955834

Strand: Reverse

Name: phoB [H]

Synonym: STH844

Alternate gene names: 51891982

Gene position: 955834-955427 (Counterclockwise)

Preceding gene: 51891996

Following gene: 51891981

Centisome position: 26.8

GC content: 69.12

Gene sequence:

>408_bases
ATGCGATCGGGGGCCGGCGCGCCCCGGAGATGGAGGGAGAGTCACATGGCGCTGATTCTGGTCGCGGACGACGACCCGGA
CATCGCACGTCTCGTCGCCTTTCACCTGAAGTACAACGGCTACGAGGTCACGCTGGCCCGCGACGGCACGGAGGCCCTGG
CGCGCGCCCGTGAGACCGCCCCCGACCTGATCCTGCTGGACTGGATGATGCCGGGCATGGACGGTCTGGAGTGCCTGACC
GCCCTGAAGGGCGATCCGGCCACGCGCGGGATCCCCGTCGTGCTCATGACCGCCCGGGCGCAGCAGGCCGATGTGCAGGC
CGGCATCGCAGCAGGCGCCGCGGCCTACCTCGTCAAGCCGTTTGAACTCGATCACCTGATCCGCACGGTCAAGGAGGCGG
TCGGATGA

Upstream 100 bases:

>100_bases
CCGGGCGCCTGGTGCGAATGGTCTATAGGGTCTGGACTGTAGATCAAAACATATCCACACAAAGTTGCTGTGTACTGGTA
CACTCAAGACATGATCCCTG

Downstream 100 bases:

>100_bases
GCGAATCGCCCTACCGCTGGGACACCGGCCTGCGACTGCGCGTCTTCGGCCTGCTGCTTTTCCTGCTCTCCCTCCTGGTC
GGGCTGGGGATCATCCTCAC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MRSGAGAPRRWRESHMALILVADDDPDIARLVAFHLKYNGYEVTLARDGTEALARARETAPDLILLDWMMPGMDGLECLT
ALKGDPATRGIPVVLMTARAQQADVQAGIAAGAAAYLVKPFELDHLIRTVKEAVG

Sequences:

>Translated_135_residues
MRSGAGAPRRWRESHMALILVADDDPDIARLVAFHLKYNGYEVTLARDGTEALARARETAPDLILLDWMMPGMDGLECLT
ALKGDPATRGIPVVLMTARAQQADVQAGIAAGAAAYLVKPFELDHLIRTVKEAVG
>Mature_135_residues
MRSGAGAPRRWRESHMALILVADDDPDIARLVAFHLKYNGYEVTLARDGTEALARARETAPDLILLDWMMPGMDGLECLT
ALKGDPATRGIPVVLMTARAQQADVQAGIAAGAAAYLVKPFELDHLIRTVKEAVG

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=41.5929203539823, Blast_Score=95, Evalue=1e-21,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=36.3636363636364, Blast_Score=78, Evalue=2e-16,
Organism=Escherichia coli, GI1788394, Length=113, Percent_Identity=35.3982300884956, Blast_Score=75, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=35.3448275862069, Blast_Score=74, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=38.4615384615385, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1789149, Length=115, Percent_Identity=33.9130434782609, Blast_Score=65, Evalue=1e-12,
Organism=Escherichia coli, GI87082012, Length=113, Percent_Identity=36.283185840708, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=34.7107438016529, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1790860, Length=104, Percent_Identity=32.6923076923077, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788713, Length=108, Percent_Identity=36.1111111111111, Blast_Score=61, Evalue=3e-11,
Organism=Escherichia coli, GI1786911, Length=111, Percent_Identity=34.2342342342342, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 14581; Mature: 14581

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGAGAPRRWRESHMALILVADDDPDIARLVAFHLKYNGYEVTLARDGTEALARARETA
CCCCCCCCHHHCCCCEEEEEEECCCCCHHHHHHHHEECCCEEEEEECCCHHHHHHHHHCC
PDLILLDWMMPGMDGLECLTALKGDPATRGIPVVLMTARAQQADVQAGIAAGAAAYLVKP
CCEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHCCC
FELDHLIRTVKEAVG
CCHHHHHHHHHHHCC
>Mature Secondary Structure
MRSGAGAPRRWRESHMALILVADDDPDIARLVAFHLKYNGYEVTLARDGTEALARARETA
CCCCCCCCHHHCCCCEEEEEEECCCCCHHHHHHHHEECCCEEEEEECCCHHHHHHHHHCC
PDLILLDWMMPGMDGLECLTALKGDPATRGIPVVLMTARAQQADVQAGIAAGAAAYLVKP
CCEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCHHHHHCCC
FELDHLIRTVKEAVG
CCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]