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The map label for this gene is dnaA [H]

Identifier: 51598691

GI number: 51598691

Start: 458789

End: 460243

Strand: Direct

Name: dnaA [H]

Synonym: BG0444

Alternate gene names: 51598691

Gene position: 458789-460243 (Clockwise)

Preceding gene: 51598687

Following gene: 51598692

Centisome position: 50.74

GC content: 27.63

Gene sequence:

>1455_bases
ATGGAAAAATCAAAAAATATATGGAGCTTGATTTTAACAGAAATAAAAAAAGAACTATCAGAAGAAGAGTTTTATGTTTG
GTTTGAAAATTTGTGCTTTTTAGAATCAATAGGTGATAATATTCAAATATCTACTCCAAATTTATTCCACAAAAATCAAA
TAGAAAAAAGATTTACAAAAAAAATCAAAGAAATCCTCACAAAAAATGGCTATAATAACGTAACAATTGTATTTACGAAT
CAACCACCTAAAACCTATTCTAGCAAACAAGAAAGTGAAAAAACAACTTTTAAAGAAACTTTGCAAAATTTTGACAAGCT
CAAAGGAAATACACTTTCTAAAGAACCAATTCAAAGCATTAAAGATCGCATAAAAATGTATATCAAAGAAGAAGAGCCTA
CAAATTTTAAAAATCCCTTTCTTAAAAAAAGATATACATTTGAAAATTTTATCATAGGACCAAATAATAGACTTGCATAC
AACGCCAGCTTATCAATCTCAAAAAATCCTGGAAAAAAATATAATCCTTGTTTAATTTACGGTGGAGTTGGACTTGGAAA
AACACATTTGCTTCAAAGCATAGGGAACAAAACAGAAGAATTACATAATAACCTAAAGATATTATACGTTACCGCTGAAA
ATTTTTTAAATGAGTTTGTAGAAAGCATAAAGACACACGAAACAAAAAAGTTTAAAAAAAAATATAGATACTTAGATATG
CTACTTATAGACGATATCCACGACTTACAAAAAAAAGAAGGCATACAAGAAGAGCTTTTTCACACATTTAACGCCCTTTA
TGAAGATAATAAACAATTAGTATTCACATGTGATCGATCTCCTTCTGAGCTTACAAATTTTACAGATCGACTAAAAAGCA
GGTTCACAAGAGGACTAAATGTTGATATATCAAAACCCAATTTTGAACTCAGAGTCGCTATTATTGAAAAAAAAGCAGAA
GAGGATGGTATAAAGGTTCCTAAAGATATACTAAATCTGGTTGCCCAAAAAGTTACAACAAATGTAAGAGATCTTGAAGC
TGCTGTAACAAAACTAAAAGCATATATAGATTTAGACAATATAGAAATTGACATTGACATTGTTGAAAAAATAATCAAAG
AAATAATAATTTACGAAAAAGAAACAACCAATGAATCAAGCAATAAAATAAATATCGAAAATATAAAAAAAATACTCTTA
AGAGAGCTAAAAATTGCACATAAAGACATTGAGGGACATAGCAAAAAACCAGAGATAACAAAAGCTAGACATATTTATGC
ATACCTTTTAAGGAATTTTACAGAGTTATCAACAGTTGAAATTGGAAAAATTATTGGGGGGAAAACCCATTCAACAGTAC
TTTATTCAATAAATAAAATAGATAGGGACAGAAATAATGACAAAGAAATCAACAATTTAATCACAGAACTTATGAACAAA
ATAAAAAAAAATTAA

Upstream 100 bases:

>100_bases
AAAATTTTTAAAACTTCACAAACAACTTAGATAGAATCCTAATTTAACATTATACTATATAATGTTAAAAGTATAGTACT
AAAACCAACAAGGACAAAAA

Downstream 100 bases:

>100_bases
ACCCAATTGAAAAATCAAACATTCTTTTAAACAATTAAAACAAATAATTTATCAAAAACACAACAAAAAATAAACTATAA
TTCAACAAGATATTTCTTTA

Product: chromosomal replication initiator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MEKSKNIWSLILTEIKKELSEEEFYVWFENLCFLESIGDNIQISTPNLFHKNQIEKRFTKKIKEILTKNGYNNVTIVFTN
QPPKTYSSKQESEKTTFKETLQNFDKLKGNTLSKEPIQSIKDRIKMYIKEEEPTNFKNPFLKKRYTFENFIIGPNNRLAY
NASLSISKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHNNLKILYVTAENFLNEFVESIKTHETKKFKKKYRYLDM
LLIDDIHDLQKKEGIQEELFHTFNALYEDNKQLVFTCDRSPSELTNFTDRLKSRFTRGLNVDISKPNFELRVAIIEKKAE
EDGIKVPKDILNLVAQKVTTNVRDLEAAVTKLKAYIDLDNIEIDIDIVEKIIKEIIIYEKETTNESSNKINIENIKKILL
RELKIAHKDIEGHSKKPEITKARHIYAYLLRNFTELSTVEIGKIIGGKTHSTVLYSINKIDRDRNNDKEINNLITELMNK
IKKN

Sequences:

>Translated_484_residues
MEKSKNIWSLILTEIKKELSEEEFYVWFENLCFLESIGDNIQISTPNLFHKNQIEKRFTKKIKEILTKNGYNNVTIVFTN
QPPKTYSSKQESEKTTFKETLQNFDKLKGNTLSKEPIQSIKDRIKMYIKEEEPTNFKNPFLKKRYTFENFIIGPNNRLAY
NASLSISKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHNNLKILYVTAENFLNEFVESIKTHETKKFKKKYRYLDM
LLIDDIHDLQKKEGIQEELFHTFNALYEDNKQLVFTCDRSPSELTNFTDRLKSRFTRGLNVDISKPNFELRVAIIEKKAE
EDGIKVPKDILNLVAQKVTTNVRDLEAAVTKLKAYIDLDNIEIDIDIVEKIIKEIIIYEKETTNESSNKINIENIKKILL
RELKIAHKDIEGHSKKPEITKARHIYAYLLRNFTELSTVEIGKIIGGKTHSTVLYSINKIDRDRNNDKEINNLITELMNK
IKKN
>Mature_484_residues
MEKSKNIWSLILTEIKKELSEEEFYVWFENLCFLESIGDNIQISTPNLFHKNQIEKRFTKKIKEILTKNGYNNVTIVFTN
QPPKTYSSKQESEKTTFKETLQNFDKLKGNTLSKEPIQSIKDRIKMYIKEEEPTNFKNPFLKKRYTFENFIIGPNNRLAY
NASLSISKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHNNLKILYVTAENFLNEFVESIKTHETKKFKKKYRYLDM
LLIDDIHDLQKKEGIQEELFHTFNALYEDNKQLVFTCDRSPSELTNFTDRLKSRFTRGLNVDISKPNFELRVAIIEKKAE
EDGIKVPKDILNLVAQKVTTNVRDLEAAVTKLKAYIDLDNIEIDIDIVEKIIKEIIIYEKETTNESSNKINIENIKKILL
RELKIAHKDIEGHSKKPEITKARHIYAYLLRNFTELSTVEIGKIIGGKTHSTVLYSINKIDRDRNNDKEINNLITELMNK
IKKN

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=480, Percent_Identity=32.2916666666667, Blast_Score=265, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 56484; Mature: 56484

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKSKNIWSLILTEIKKELSEEEFYVWFENLCFLESIGDNIQISTPNLFHKNQIEKRFTK
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHH
KIKEILTKNGYNNVTIVFTNQPPKTYSSKQESEKTTFKETLQNFDKLKGNTLSKEPIQSI
HHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KDRIKMYIKEEEPTNFKNPFLKKRYTFENFIIGPNNRLAYNASLSISKNPGKKYNPCLIY
HHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEECCCCCEEEEEEEEEECCCCCCCCCEEEE
GGVGLGKTHLLQSIGNKTEELHNNLKILYVTAENFLNEFVESIKTHETKKFKKKYRYLDM
CCCCCCHHHHHHHHCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIDDIHDLQKKEGIQEELFHTFNALYEDNKQLVFTCDRSPSELTNFTDRLKSRFTRGLN
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCC
VDISKPNFELRVAIIEKKAEEDGIKVPKDILNLVAQKVTTNVRDLEAAVTKLKAYIDLDN
EEECCCCCEEEEEEEEHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECC
IEIDIDIVEKIIKEIIIYEKETTNESSNKINIENIKKILLRELKIAHKDIEGHSKKPEIT
CEEEHHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
KARHIYAYLLRNFTELSTVEIGKIIGGKTHSTVLYSINKIDRDRNNDKEINNLITELMNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHH
IKKN
HHCC
>Mature Secondary Structure
MEKSKNIWSLILTEIKKELSEEEFYVWFENLCFLESIGDNIQISTPNLFHKNQIEKRFTK
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHH
KIKEILTKNGYNNVTIVFTNQPPKTYSSKQESEKTTFKETLQNFDKLKGNTLSKEPIQSI
HHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
KDRIKMYIKEEEPTNFKNPFLKKRYTFENFIIGPNNRLAYNASLSISKNPGKKYNPCLIY
HHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEECCCCCEEEEEEEEEECCCCCCCCCEEEE
GGVGLGKTHLLQSIGNKTEELHNNLKILYVTAENFLNEFVESIKTHETKKFKKKYRYLDM
CCCCCCHHHHHHHHCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIDDIHDLQKKEGIQEELFHTFNALYEDNKQLVFTCDRSPSELTNFTDRLKSRFTRGLN
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCC
VDISKPNFELRVAIIEKKAEEDGIKVPKDILNLVAQKVTTNVRDLEAAVTKLKAYIDLDN
EEECCCCCEEEEEEEEHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEECC
IEIDIDIVEKIIKEIIIYEKETTNESSNKINIENIKKILLRELKIAHKDIEGHSKKPEIT
CEEEHHHHHHHHHHHHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
KARHIYAYLLRNFTELSTVEIGKIIGGKTHSTVLYSINKIDRDRNNDKEINNLITELMNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHH
IKKN
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA