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The map label for this gene is add

Identifier: 51596506

GI number: 51596506

Start: 2565873

End: 2566877

Strand: Reverse

Name: add

Synonym: YPTB2180

Alternate gene names: 51596506

Gene position: 2566877-2565873 (Counterclockwise)

Preceding gene: 51596508

Following gene: 51596499

Centisome position: 54.1

GC content: 50.45

Gene sequence:

>1005_bases
ATGATTGATCCTCGCCTTCCTCTGACCGACATTCATCGCCACCTTGATGGCAATATCCGAGCGCAAACCATTTTGGACTT
GGGTCAACAATTTAATTTGAATTTACCGGCCAATGAGCTTGATACGCTGAGACCACACGTACAAATCACCAAGACCGAGC
CAGATTTGGTCAGTTTCCTACAAAAGTTGGATTGGGGCGTTGCAGTTCTCGGATCACTGGATGCCTGTCGCCGAGTGGCT
TATGAGAATGTCGAAGACGCAGCACATGCTGGTTTACATTATGCTGAACTCCGCTTTTCCCCGTTTTATATGGCGATGAA
ACACCAACTACCGATTACCGGTGTTGTCGAAGCGGTTATTGATGGCATTGCGTCTGGTTGTCGCGATTTTAATATTGATA
TCCGTTTGATCGGCATTCTCAGCCGCACCTTCGGTGAACAAGCGTGTTTGCAAGAACTTGATAGCTTGCTGGCCCATCGC
GAAGGGATAACCGCGCTGGATTTAGCCGGTGACGAGTTAGGTTTTCCCGGTTCTCTGTTCCGCCGCCATTTTAATCGAGC
GAGGGATGCGGGCCTACGTATTACCGTCCATGCGGGTGAAGCGGCCGGTCCGGAGAGTATCTGGCAAGCTATTCGTGAAC
TGGGTGCTGAACGTATCGGCCACGGCGTTAAAGCCGTCGAAGACCGTAAGTTGATGGACTATCTGGCAGAACACAAAATA
GGTATCGAATCCTGCCTGACCTCCAATATCCAAACCAGCACTGTAGTCTCTCTGGCAACCCATCCATTAGCAACCTTCCT
ACGCCATGGCATCGTGGCATCAATTAACACTGATGACCCGGCGGTTCAGGGCATTGAAATTGCCAATGAATACCTTGTCG
CTGCACCGGCTGCGGGGCTAACGCCGCATGAAATCCGCCAAGCACAAGCGAATGGCCTGGAAATGGCATTTATCAGCGAA
CAAGAAAAGCAGGCACTGCGGGATAAAGTATTCCCTATTTCCTGA

Upstream 100 bases:

>100_bases
TTTTTTATGTAACACTATGGATATTTTCATTCGTTTGTTTTTATAATATTCTGCACCTTATCTACCGAAATCTATCTTTG
ATAAAAAGTGAGTGCACAGC

Downstream 100 bases:

>100_bases
GGTACGATAGAACCCGAAGATACGATAAAATAAAAAAGCGCCCATACCCTAGAGTGGTACCGGCGCTTTCTATTTTCATC
ACTAAGCCCTTTTTATCGCC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIDPRLPLTDIHRHLDGNIRAQTILDLGQQFNLNLPANELDTLRPHVQITKTEPDLVSFLQKLDWGVAVLGSLDACRRVA
YENVEDAAHAGLHYAELRFSPFYMAMKHQLPITGVVEAVIDGIASGCRDFNIDIRLIGILSRTFGEQACLQELDSLLAHR
EGITALDLAGDELGFPGSLFRRHFNRARDAGLRITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRKLMDYLAEHKI
GIESCLTSNIQTSTVVSLATHPLATFLRHGIVASINTDDPAVQGIEIANEYLVAAPAAGLTPHEIRQAQANGLEMAFISE
QEKQALRDKVFPIS

Sequences:

>Translated_334_residues
MIDPRLPLTDIHRHLDGNIRAQTILDLGQQFNLNLPANELDTLRPHVQITKTEPDLVSFLQKLDWGVAVLGSLDACRRVA
YENVEDAAHAGLHYAELRFSPFYMAMKHQLPITGVVEAVIDGIASGCRDFNIDIRLIGILSRTFGEQACLQELDSLLAHR
EGITALDLAGDELGFPGSLFRRHFNRARDAGLRITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRKLMDYLAEHKI
GIESCLTSNIQTSTVVSLATHPLATFLRHGIVASINTDDPAVQGIEIANEYLVAAPAAGLTPHEIRQAQANGLEMAFISE
QEKQALRDKVFPIS
>Mature_334_residues
MIDPRLPLTDIHRHLDGNIRAQTILDLGQQFNLNLPANELDTLRPHVQITKTEPDLVSFLQKLDWGVAVLGSLDACRRVA
YENVEDAAHAGLHYAELRFSPFYMAMKHQLPITGVVEAVIDGIASGCRDFNIDIRLIGILSRTFGEQACLQELDSLLAHR
EGITALDLAGDELGFPGSLFRRHFNRARDAGLRITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRKLMDYLAEHKI
GIESCLTSNIQTSTVVSLATHPLATFLRHGIVASINTDDPAVQGIEIANEYLVAAPAAGLTPHEIRQAQANGLEMAFISE
QEKQALRDKVFPIS

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=342, Percent_Identity=30.9941520467836, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1787910, Length=330, Percent_Identity=76.969696969697, Blast_Score=529, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI32565969, Length=338, Percent_Identity=30.4733727810651, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17538512, Length=338, Percent_Identity=30.4733727810651, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6324188, Length=335, Percent_Identity=26.865671641791, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24645260, Length=330, Percent_Identity=25.4545454545455, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006650
- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36650; Mature: 36650

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00485 A_DEAMINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDPRLPLTDIHRHLDGNIRAQTILDLGQQFNLNLPANELDTLRPHVQITKTEPDLVSFL
CCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEECCCHHHHHHH
QKLDWGVAVLGSLDACRRVAYENVEDAAHAGLHYAELRFSPFYMAMKHQLPITGVVEAVI
HHHCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHCCCHHHHHHHHCCCHHHHHHHHH
DGIASGCRDFNIDIRLIGILSRTFGEQACLQELDSLLAHREGITALDLAGDELGFPGSLF
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHH
RRHFNRARDAGLRITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRKLMDYLAEHKI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
GIESCLTSNIQTSTVVSLATHPLATFLRHGIVASINTDDPAVQGIEIANEYLVAAPAAGL
CHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHEECCCCCC
TPHEIRQAQANGLEMAFISEQEKQALRDKVFPIS
CHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIDPRLPLTDIHRHLDGNIRAQTILDLGQQFNLNLPANELDTLRPHVQITKTEPDLVSFL
CCCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEECCCHHHHHHH
QKLDWGVAVLGSLDACRRVAYENVEDAAHAGLHYAELRFSPFYMAMKHQLPITGVVEAVI
HHHCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHCCCHHHHHHHHCCCHHHHHHHHH
DGIASGCRDFNIDIRLIGILSRTFGEQACLQELDSLLAHREGITALDLAGDELGFPGSLF
HHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHH
RRHFNRARDAGLRITVHAGEAAGPESIWQAIRELGAERIGHGVKAVEDRKLMDYLAEHKI
HHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCC
GIESCLTSNIQTSTVVSLATHPLATFLRHGIVASINTDDPAVQGIEIANEYLVAAPAAGL
CHHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHEECCCCCC
TPHEIRQAQANGLEMAFISEQEKQALRDKVFPIS
CHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA