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The map label for this gene is mdtJ [H]

Identifier: 51596377

GI number: 51596377

Start: 2417992

End: 2418456

Strand: Direct

Name: mdtJ [H]

Synonym: YPTB2051

Alternate gene names: 51596377

Gene position: 2417992-2418456 (Clockwise)

Preceding gene: 51596376

Following gene: 51596378

Centisome position: 50.96

GC content: 46.24

Gene sequence:

>465_bases
ATGCGTGTTAGGAGAAGAAAAGTGATTTATTGGATATTTTTAGGTCTGGCAATTATTGCTGAAATTATTGGCACCCTATC
AATGAAATATGCCAGTGTTAGCGGCGAGATGACCGGGCATGTCGTGATGTATTTTATGATAACGGGTTCCTATGTCATGC
TCTCGTTAGCGGTTAAGAAAGTAGCATTGGGTGTGGCTTATGCGCTGTGGGAGGGGATCGGCATCCTTATTATTACTATT
TTCAGTGTGATGTGGTTTGGCGAGACGTTATCGCCACTGAAAATAGCCGGTTTAGTGACACTGATTGGTGGGATCCTCTT
GGTGAAATCGGGTACGCGGAAACCAAAACAACCGAACCGCCATCGCGGTAATCGACCCCCTTCGGTACAGGGATTAAAAA
CACAGACTACCGGCCATCATAAGGGTGTTGCTGTTGAGTCAGGTGAGCATCATGCAGCAGCTTGA

Upstream 100 bases:

>100_bases
CCAAGTGAGTATCTATTTCTTACGGACTGCGCAGGTTTATTCCTTGTGAATAAGGCACTGAAGCAGGATAGCCGTAACAA
ATAGACCTTAGCGTGCGTTT

Downstream 100 bases:

>100_bases
GTTTTACCCTATAGCTTTCTTGATCTTGGCCGTTATGCTGGAAATCGTCGCTAATATCTTGCTGAAAATGTCAGATGGCT
TTCGCCGAAAATGGTTGGGG

Product: DMT superfamily drug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MRVRRRKVIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHVVMYFMITGSYVMLSLAVKKVALGVAYALWEGIGILIITI
FSVMWFGETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNRHRGNRPPSVQGLKTQTTGHHKGVAVESGEHHAAA

Sequences:

>Translated_154_residues
MRVRRRKVIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHVVMYFMITGSYVMLSLAVKKVALGVAYALWEGIGILIITI
FSVMWFGETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNRHRGNRPPSVQGLKTQTTGHHKGVAVESGEHHAAA
>Mature_154_residues
MRVRRRKVIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHVVMYFMITGSYVMLSLAVKKVALGVAYALWEGIGILIITI
FSVMWFGETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNRHRGNRPPSVQGLKTQTTGHHKGVAVESGEHHAAA

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=111, Percent_Identity=66.6666666666667, Blast_Score=142, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 16770; Mature: 16770

Theoretical pI: Translated: 11.03; Mature: 11.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRRRKVIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHVVMYFMITGSYVMLSLAVKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VALGVAYALWEGIGILIITIFSVMWFGETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCC
HRGNRPPSVQGLKTQTTGHHKGVAVESGEHHAAA
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MRVRRRKVIYWIFLGLAIIAEIIGTLSMKYASVSGEMTGHVVMYFMITGSYVMLSLAVKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VALGVAYALWEGIGILIITIFSVMWFGETLSPLKIAGLVTLIGGILLVKSGTRKPKQPNR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCC
HRGNRPPSVQGLKTQTTGHHKGVAVESGEHHAAA
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA