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The map label for this gene is mdtI [H]

Identifier: 51596378

GI number: 51596378

Start: 2418443

End: 2418772

Strand: Direct

Name: mdtI [H]

Synonym: YPTB2052

Alternate gene names: 51596378

Gene position: 2418443-2418772 (Clockwise)

Preceding gene: 51596377

Following gene: 51596380

Centisome position: 50.97

GC content: 47.58

Gene sequence:

>330_bases
ATGCAGCAGCTTGAGTTTTACCCTATAGCTTTCTTGATCTTGGCCGTTATGCTGGAAATCGTCGCTAATATCTTGCTGAA
AATGTCAGATGGCTTTCGCCGAAAATGGTTGGGGATATTGTCCCTGTTGTCAGTATTAGGCGCATTCAGTGCGTTGGCGC
AAGCAGTGAAGGGGATTGAGCTGTCGGTAGCTTATGCCATGTGGGGCGGTTTTGGTATTGCGGCCACTGTTGCAGCGGGC
TGGATTCTGTTTAATCAACGGTTGAACTACAAAGGTTGGATTGGTTTGATCTTACTGCTGGCGGGCATGGTGATGATTAA
GTTGTCATAG

Upstream 100 bases:

>100_bases
CCGAACCGCCATCGCGGTAATCGACCCCCTTCGGTACAGGGATTAAAAACACAGACTACCGGCCATCATAAGGGTGTTGC
TGTTGAGTCAGGTGAGCATC

Downstream 100 bases:

>100_bases
CGGGGCCAGAGGCAGTAAGCGGAGGGTAGCCTGGCGGCTACTCTCCTTTGTTTTTGTGGCTTAGTGACATTGGTTACTTA
GTGACATTTATCGTTTAGCA

Product: multidrug efflux system protein MdtI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYAMWGGFGIAATVAAG
WILFNQRLNYKGWIGLILLLAGMVMIKLS

Sequences:

>Translated_109_residues
MQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYAMWGGFGIAATVAAG
WILFNQRLNYKGWIGLILLLAGMVMIKLS
>Mature_109_residues
MQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIELSVAYAMWGGFGIAATVAAG
WILFNQRLNYKGWIGLILLLAGMVMIKLS

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787883, Length=109, Percent_Identity=73.394495412844, Blast_Score=143, Evalue=3e-36,
Organism=Escherichia coli, GI1786755, Length=101, Percent_Identity=34.6534653465347, Blast_Score=66, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11935; Mature: 11935

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
LSVAYAMWGGFGIAATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQQLEFYPIAFLILAVMLEIVANILLKMSDGFRRKWLGILSLLSVLGAFSALAQAVKGIE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
LSVAYAMWGGFGIAATVAAGWILFNQRLNYKGWIGLILLLAGMVMIKLS
HHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA