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The map label for this gene is yjmB [H]

Identifier: 50843766

GI number: 50843766

Start: 2533422

End: 2534846

Strand: Direct

Name: yjmB [H]

Synonym: PPA2331

Alternate gene names: 50843766

Gene position: 2533422-2534846 (Clockwise)

Preceding gene: 50843749

Following gene: 50843767

Centisome position: 98.95

GC content: 55.44

Gene sequence:

>1425_bases
ATGTCGACCATCACAACGAAAGGCCAGAAGGCTAAGGCGGTGAATGCTCGCGATTTCGATATTCGCGACATGATTGGCTA
CGCGCTTGGCGATGTGGGCAACAATTTCACCTTCAACTTGGTGAATTCGTTCCTCATGATTTTCTACACCAATGTTTTCG
GTCTTGCCGCGGCGCTGGTGGGAGCATTGTTTATGGCTGCCCGTCTCGTTGACGCCTTCGTCGACATCATGGTCGGCCGC
CTTATCGACAACTCGAAGATGACCAAACGCGGACGCTTCACCCCGTGGGTCATGCGCATGAAGTTTCCGCTTGCTGCCTC
CGCCATTCTCCTCTTTCTGCCAGCTGCCGGCCACCTTCCCATGACGACACGTGTGGTCTACGCCTTCGTCACCTACCTGG
CCTGGGGCATCTTCTACTCCTTTGTCAATATCCCCTATGGATCCATGGCGTCAGCCATCTCCGGGAAGCCGCGCGACAAG
ACCTCGCTATCCACCGCACGGAGCATTGGCTCGGCTTCAGGCGCCGCCATCGTTAGCTATGTCGTGCCGCTTATTATGTA
CGGCAGCAACTCTCATCAGATCAACCCGCATCGATTCTTTACGGGAGCGGCTATTTTCGCCGTCCTTGGCTTGTTCTGCT
ACATCGGTCTGACGATGCTGACCGTCGAGCGTATTCGAATTGACAAGACGGAGCGCGTCCCACTGGGCAAGATGTTCTCT
GAAATGGCACACAATAAAGCCCTCGTCATGCTGGTCCTTATTGATATCGTTGTCGTCATCAACCAGAATCTTTCTGGTAT
CACGCTGACCTATCTTTTCAATGATTATTTCCAGAATAAGACTGCGATGTCTATTGCTCTAGTATTCAATTTCACAACTG
TTATTCTAGTAGCTCCTTTCGCGCAGACCCTGGTTCGGAATTTCGGTCGAAAAGAATCGGCAGCAGTGGCATTATTCTTC
GGCGCCGCCATGTACGGTCTGATGCTCATCATCCACACCCACAGCCCCTGGATTTTCCTTGTTGACCTCTTCTTCGGCTC
ACTTGGCGCCGGCGTGTTCAACCTCATGGTGTGGGCCTTCATTACCGACGTCATCGATGCCCAGGAGGTCATGTCCGGGG
AGCGTGAAGACGGTGTCATCTATGGCGTGAACTCCTTCGCCCGCAAGCTTGCCCAGGCCATTGCCGGTGGAATCGGCGGA
GCCATGCTGACGATGATCGGCTACCAGTCCTCCTCCCAAGGTGGTGCCGTTCAGTCGGAGTCCGTCGTCAATCACCTGTA
CACGCTCGCCACCGCCATCCCGACGATCTGCTGCCTCGGCGCTGCCCTGCTCATGCTGGGCTACCCGCTCACCCGCGACA
AGGTGGTCGCCAACGCCGACGAGTTGGCTCGTCGCCACGCAGTACAGGCCGAGCAAAACTCCTGA

Upstream 100 bases:

>100_bases
CCTTGACACTCCGGTGCGAATCTCTAGACAAGGCGATGCTGCCTGTCCACAATGCTGTGACGATAATCGTCGCAGCCTTG
AATAGCATAGAGGGTTGTCA

Downstream 100 bases:

>100_bases
CCCATAACGGAGGCACATCATGGACACGCTCATGCGGATCACCGACCACTTGACAACCTCGCCGGGTATCCAATTGAAAA
TTGACAAGCGATGGGGTGCC

Product: glucuronide permease

Products: Proton [Cytoplasm]; Glucuronides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MSTITTKGQKAKAVNARDFDIRDMIGYALGDVGNNFTFNLVNSFLMIFYTNVFGLAAALVGALFMAARLVDAFVDIMVGR
LIDNSKMTKRGRFTPWVMRMKFPLAASAILLFLPAAGHLPMTTRVVYAFVTYLAWGIFYSFVNIPYGSMASAISGKPRDK
TSLSTARSIGSASGAAIVSYVVPLIMYGSNSHQINPHRFFTGAAIFAVLGLFCYIGLTMLTVERIRIDKTERVPLGKMFS
EMAHNKALVMLVLIDIVVVINQNLSGITLTYLFNDYFQNKTAMSIALVFNFTTVILVAPFAQTLVRNFGRKESAAVALFF
GAAMYGLMLIIHTHSPWIFLVDLFFGSLGAGVFNLMVWAFITDVIDAQEVMSGEREDGVIYGVNSFARKLAQAIAGGIGG
AMLTMIGYQSSSQGGAVQSESVVNHLYTLATAIPTICCLGAALLMLGYPLTRDKVVANADELARRHAVQAEQNS

Sequences:

>Translated_474_residues
MSTITTKGQKAKAVNARDFDIRDMIGYALGDVGNNFTFNLVNSFLMIFYTNVFGLAAALVGALFMAARLVDAFVDIMVGR
LIDNSKMTKRGRFTPWVMRMKFPLAASAILLFLPAAGHLPMTTRVVYAFVTYLAWGIFYSFVNIPYGSMASAISGKPRDK
TSLSTARSIGSASGAAIVSYVVPLIMYGSNSHQINPHRFFTGAAIFAVLGLFCYIGLTMLTVERIRIDKTERVPLGKMFS
EMAHNKALVMLVLIDIVVVINQNLSGITLTYLFNDYFQNKTAMSIALVFNFTTVILVAPFAQTLVRNFGRKESAAVALFF
GAAMYGLMLIIHTHSPWIFLVDLFFGSLGAGVFNLMVWAFITDVIDAQEVMSGEREDGVIYGVNSFARKLAQAIAGGIGG
AMLTMIGYQSSSQGGAVQSESVVNHLYTLATAIPTICCLGAALLMLGYPLTRDKVVANADELARRHAVQAEQNS
>Mature_473_residues
STITTKGQKAKAVNARDFDIRDMIGYALGDVGNNFTFNLVNSFLMIFYTNVFGLAAALVGALFMAARLVDAFVDIMVGRL
IDNSKMTKRGRFTPWVMRMKFPLAASAILLFLPAAGHLPMTTRVVYAFVTYLAWGIFYSFVNIPYGSMASAISGKPRDKT
SLSTARSIGSASGAAIVSYVVPLIMYGSNSHQINPHRFFTGAAIFAVLGLFCYIGLTMLTVERIRIDKTERVPLGKMFSE
MAHNKALVMLVLIDIVVVINQNLSGITLTYLFNDYFQNKTAMSIALVFNFTTVILVAPFAQTLVRNFGRKESAAVALFFG
AAMYGLMLIIHTHSPWIFLVDLFFGSLGAGVFNLMVWAFITDVIDAQEVMSGEREDGVIYGVNSFARKLAQAIAGGIGGA
MLTMIGYQSSSQGGAVQSESVVNHLYTLATAIPTICCLGAALLMLGYPLTRDKVVANADELARRHAVQAEQNS

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI122937339, Length=472, Percent_Identity=23.9406779661017, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1787902, Length=461, Percent_Identity=30.1518438177874, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1786466, Length=460, Percent_Identity=25.2173913043478, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI145693206, Length=493, Percent_Identity=24.7464503042596, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI48994989, Length=456, Percent_Identity=26.3157894736842, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87082306, Length=464, Percent_Identity=23.4913793103448, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1790561, Length=429, Percent_Identity=24.2424242424242, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51551; Mature: 51420

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
STITTKGQKAKAVNARDFDIRDMIGYALGDVGNNFTFNLVNSFLMIFYTNVFGLAAALV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Glucuronides [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Glucuronides [Periplasm] = Proton [Cytoplasm] + Glucuronides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]