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The map label for this gene is fixB [H]

Identifier: 50843648

GI number: 50843648

Start: 2397552

End: 2398430

Strand: Reverse

Name: fixB [H]

Synonym: PPA2213

Alternate gene names: 50843648

Gene position: 2398430-2397552 (Counterclockwise)

Preceding gene: 50843649

Following gene: 50843647

Centisome position: 93.68

GC content: 56.88

Gene sequence:

>879_bases
ATGTCGACGAGTTGGATTGTCACTGCGCAGCCAAACATTTCTCATATGCTGGAGTTGACTGGCCAAAGAGGTGACAGCAC
GGTCGTAGTGGCTGTTGGTGTGGCTGCCGATCGTTTTTCCGGGGCCGATCGCGTTGTTCAGATTGAACTTCCGGCAGCGG
TGCCGGTCGAGGCGGTGGCTGGATTCGCGGCGGAACAGGTCGCAGCTGAGCCCGGCGATGTGGTCCTTGCTGGCACTTCT
TCTGCGGACCGTGTTCTTGCAGCTGCGGTGGCTGTCCAGCTTGACGCACCTATTTATCGTGGTCTGCAAGAGCTGGAAGC
TGGCAAGGCTACTGTGCTGCAGTTGGGTGGTGTGTTGGAGCAGACGCTCTCGCTTTCCACGCCGATCGTGTTCGTGTGCG
AACCTGGGGGGCCATCTGAGGGACCATGCCCTGAGCTGACGCAGGTGAGCGCAACCGTAGATGGGGCCACCGTGGTCTCC
AGTGACAAGGCTGGTAGCCAGGCCACGAATCTGGCTGCTGCGAAACGCATTGTTGCTTGTGGACGCGGTTTTCGTGAGGA
GGCAGACCTTCATATTGCGCATGACTTGGCTGCACAGTTAGGTGCGGAGCTCGCGTGTTCGCGTCCTCTAGCTGAAGGGG
TGAGCTGGTTTGAGAAGAAACTCTACGTAGGAATCTCCGGAGCACAGGTTTCACCTGAGCTCTACATTGCGGTGGGAATT
TCTGGCCAGCTGCAGCATGTTGTCGGCATGAATAAGTCCCAGACTGTCGTCGCTATCAATTCGGATTCAGATGCGCCTAT
TTTTGAGCAGGCTGATTATGGAATTGTCGGAGACCTCTATGCAGTTCTTCCCGAGCTGACAAAGGCATTGGCGCGATGA

Upstream 100 bases:

>100_bases
AAGTGTTCAGTGGGGATGGTGCTGCTGCCCAACTTGTTGCTGCACTCCGTGATGCATCGGTCATTTGACAAGAATTAAAC
AGGCGTGAAAGGGAGTCTTG

Downstream 100 bases:

>100_bases
CTGGGATCGCAGAACTGTTGCGGGGTGTGGGCTCCCAGCCTTCGGAGACACCGCCGCCGTTGTGGGATGTCCCGGGCGTT
GAGCCTGATTTCGATGTCAT

Product: putative electron transfer flavoprotein, carnitine metabolism (FixB protein)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSTSWIVTAQPNISHMLELTGQRGDSTVVVAVGVAADRFSGADRVVQIELPAAVPVEAVAGFAAEQVAAEPGDVVLAGTS
SADRVLAAAVAVQLDAPIYRGLQELEAGKATVLQLGGVLEQTLSLSTPIVFVCEPGGPSEGPCPELTQVSATVDGATVVS
SDKAGSQATNLAAAKRIVACGRGFREEADLHIAHDLAAQLGAELACSRPLAEGVSWFEKKLYVGISGAQVSPELYIAVGI
SGQLQHVVGMNKSQTVVAINSDSDAPIFEQADYGIVGDLYAVLPELTKALAR

Sequences:

>Translated_292_residues
MSTSWIVTAQPNISHMLELTGQRGDSTVVVAVGVAADRFSGADRVVQIELPAAVPVEAVAGFAAEQVAAEPGDVVLAGTS
SADRVLAAAVAVQLDAPIYRGLQELEAGKATVLQLGGVLEQTLSLSTPIVFVCEPGGPSEGPCPELTQVSATVDGATVVS
SDKAGSQATNLAAAKRIVACGRGFREEADLHIAHDLAAQLGAELACSRPLAEGVSWFEKKLYVGISGAQVSPELYIAVGI
SGQLQHVVGMNKSQTVVAINSDSDAPIFEQADYGIVGDLYAVLPELTKALAR
>Mature_291_residues
STSWIVTAQPNISHMLELTGQRGDSTVVVAVGVAADRFSGADRVVQIELPAAVPVEAVAGFAAEQVAAEPGDVVLAGTSS
ADRVLAAAVAVQLDAPIYRGLQELEAGKATVLQLGGVLEQTLSLSTPIVFVCEPGGPSEGPCPELTQVSATVDGATVVSS
DKAGSQATNLAAAKRIVACGRGFREEADLHIAHDLAAQLGAELACSRPLAEGVSWFEKKLYVGISGAQVSPELYIAVGIS
GQLQHVVGMNKSQTVVAINSDSDAPIFEQADYGIVGDLYAVLPELTKALAR

Specific function: Required for anaerobic carnitine reduction. May bring reductant to CaiA [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=127, Percent_Identity=46.4566929133858, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI4503607, Length=127, Percent_Identity=46.4566929133858, Blast_Score=115, Evalue=4e-26,
Organism=Escherichia coli, GI1786226, Length=266, Percent_Identity=37.593984962406, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787990, Length=248, Percent_Identity=36.6935483870968, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI87082157, Length=269, Percent_Identity=32.3420074349442, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17506929, Length=125, Percent_Identity=45.6, Blast_Score=114, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6325261, Length=128, Percent_Identity=39.84375, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17136898, Length=132, Percent_Identity=46.2121212121212, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24652801, Length=132, Percent_Identity=46.2121212121212, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 29999; Mature: 29868

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSWIVTAQPNISHMLELTGQRGDSTVVVAVGVAADRFSGADRVVQIELPAAVPVEAVA
CCCCEEEEECCCHHHHHHCCCCCCCCEEEEEEEEEHHCCCCCCEEEEEEECCCCCHHHHH
GFAAEQVAAEPGDVVLAGTSSADRVLAAAVAVQLDAPIYRGLQELEAGKATVLQLGGVLE
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHEECCHHHHHHHHHHCCCHHHHHHHHHHH
QTLSLSTPIVFVCEPGGPSEGPCPELTQVSATVDGATVVSSDKAGSQATNLAAAKRIVAC
HHHCCCCCEEEEECCCCCCCCCCCCHHEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHH
GRGFREEADLHIAHDLAAQLGAELACSRPLAEGVSWFEKKLYVGISGAQVSPELYIAVGI
CCCCCCCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHEEEEEECCCEECCEEEEEEEC
SGQLQHVVGMNKSQTVVAINSDSDAPIFEQADYGIVGDLYAVLPELTKALAR
CCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STSWIVTAQPNISHMLELTGQRGDSTVVVAVGVAADRFSGADRVVQIELPAAVPVEAVA
CCCEEEEECCCHHHHHHCCCCCCCCEEEEEEEEEHHCCCCCCEEEEEEECCCCCHHHHH
GFAAEQVAAEPGDVVLAGTSSADRVLAAAVAVQLDAPIYRGLQELEAGKATVLQLGGVLE
HHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHEECCHHHHHHHHHHCCCHHHHHHHHHHH
QTLSLSTPIVFVCEPGGPSEGPCPELTQVSATVDGATVVSSDKAGSQATNLAAAKRIVAC
HHHCCCCCEEEEECCCCCCCCCCCCHHEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHH
GRGFREEADLHIAHDLAAQLGAELACSRPLAEGVSWFEKKLYVGISGAQVSPELYIAVGI
CCCCCCCCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHEEEEEECCCEECCEEEEEEEC
SGQLQHVVGMNKSQTVVAINSDSDAPIFEQADYGIVGDLYAVLPELTKALAR
CCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA