Click here to switch to the map view.

The map label for this gene is nudF [H]

Identifier: 50842871

GI number: 50842871

Start: 1508736

End: 1509395

Strand: Reverse

Name: nudF [H]

Synonym: PPA1389

Alternate gene names: 50842871

Gene position: 1509395-1508736 (Counterclockwise)

Preceding gene: 50842872

Following gene: 50842870

Centisome position: 58.95

GC content: 61.36

Gene sequence:

>660_bases
GTGAGTCAGGAGCGCTGGGATAAGGACGAGTATTGGCAGGTCGTTGACCACCAGGTAAAGGCCACGGGACAGGTGTGCGA
TTTCATTGATGACGCGGTCATTACCCCGTCGGGGGAGCGGATCAACCGTCAATACGTGAGCCACCCCGGCGCAGTCGGCA
TCATCGCCCTTGACGATCAGGATCGCGTCGCGGTCGTCAGACAGTATCGTCACCCGGTGCGCATGGTGTTGGTCGAGCCG
CCGGCTGGCCTGCTCGATGTCGAGGGAGAAGACTTTCTAGCGGCTGCCCAGCGTGAATTGGCTGAGGAGGCCATGTTGTC
GGCCGACGATTGGCGGGTTCTCGTCGACATCGTCACCACTCCGGGCGGGTGCCAGGAGTCTTTGCGTATTTACCTGGCCC
GGGGTCTTCATGAGGTACCGCGTCCCGAGGGATTCCTGCTAGAAGGCGAGGAAGTGTCGATGAAGGCTGGTTGGGAGCCG
TTGGACGACCTTGTCGAGGCAATTTACGCCGGGCAATGCCAGTCTCCCACCCTCGTGACGGGCGTGATGGCTTTGGAACT
GGCTCGTCGCACTGATCGAGTTAACGAGCTGCGTCCCGCTCATGCGCCGTGGCCGATTCGGGAGCGTCCTGGTGGTATTG
ACGGAGTTCGCGCAGAGTGA

Upstream 100 bases:

>100_bases
CCCACCCGCTGTTCCGCGGACTCGTCGCAGCGGCCGTCGGGCATGCCAAAGCAGCATCGAAGGGAGCGGCCAAGGAGTCC
TCCACCAAGGTGGCCGACAA

Downstream 100 bases:

>100_bases
CCTCGTTGGTCGGCGGTCAGGCCGAGGATTACTTGCGTCACCTTGTAGTGGAGCGGGGTCTGTCCGATAACACGGTGCAG
GCCTACCGACGTGATCTGTT

Product: putative ADP-ribose pyrophosphatase

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSQERWDKDEYWQVVDHQVKATGQVCDFIDDAVITPSGERINRQYVSHPGAVGIIALDDQDRVAVVRQYRHPVRMVLVEP
PAGLLDVEGEDFLAAAQRELAEEAMLSADDWRVLVDIVTTPGGCQESLRIYLARGLHEVPRPEGFLLEGEEVSMKAGWEP
LDDLVEAIYAGQCQSPTLVTGVMALELARRTDRVNELRPAHAPWPIRERPGGIDGVRAE

Sequences:

>Translated_219_residues
MSQERWDKDEYWQVVDHQVKATGQVCDFIDDAVITPSGERINRQYVSHPGAVGIIALDDQDRVAVVRQYRHPVRMVLVEP
PAGLLDVEGEDFLAAAQRELAEEAMLSADDWRVLVDIVTTPGGCQESLRIYLARGLHEVPRPEGFLLEGEEVSMKAGWEP
LDDLVEAIYAGQCQSPTLVTGVMALELARRTDRVNELRPAHAPWPIRERPGGIDGVRAE
>Mature_218_residues
SQERWDKDEYWQVVDHQVKATGQVCDFIDDAVITPSGERINRQYVSHPGAVGIIALDDQDRVAVVRQYRHPVRMVLVEPP
AGLLDVEGEDFLAAAQRELAEEAMLSADDWRVLVDIVTTPGGCQESLRIYLARGLHEVPRPEGFLLEGEEVSMKAGWEPL
DDLVEAIYAGQCQSPTLVTGVMALELARRTDRVNELRPAHAPWPIRERPGGIDGVRAE

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 24431; Mature: 24300

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQERWDKDEYWQVVDHQVKATGQVCDFIDDAVITPSGERINRQYVSHPGAVGIIALDDQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCCEEEEEECCC
DRVAVVRQYRHPVRMVLVEPPAGLLDVEGEDFLAAAQRELAEEAMLSADDWRVLVDIVTT
CHHHHHHHHCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
PGGCQESLRIYLARGLHEVPRPEGFLLEGEEVSMKAGWEPLDDLVEAIYAGQCQSPTLVT
CCCHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCHHHHHHHHHCCCCCCCHHHH
GVMALELARRTDRVNELRPAHAPWPIRERPGGIDGVRAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SQERWDKDEYWQVVDHQVKATGQVCDFIDDAVITPSGERINRQYVSHPGAVGIIALDDQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCCEEEEEECCC
DRVAVVRQYRHPVRMVLVEPPAGLLDVEGEDFLAAAQRELAEEAMLSADDWRVLVDIVTT
CHHHHHHHHCCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECC
PGGCQESLRIYLARGLHEVPRPEGFLLEGEEVSMKAGWEPLDDLVEAIYAGQCQSPTLVT
CCCHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCCCCHHHHHHHHHCCCCCCCHHHH
GVMALELARRTDRVNELRPAHAPWPIRERPGGIDGVRAE
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]