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The map label for this gene is xerD

Identifier: 50842870

GI number: 50842870

Start: 1507819

End: 1508739

Strand: Reverse

Name: xerD

Synonym: PPA1388

Alternate gene names: 50842870

Gene position: 1508739-1507819 (Counterclockwise)

Preceding gene: 50842871

Following gene: 50842869

Centisome position: 58.93

GC content: 61.35

Gene sequence:

>921_bases
GTGACCTCGTTGGTCGGCGGTCAGGCCGAGGATTACTTGCGTCACCTTGTAGTGGAGCGGGGTCTGTCCGATAACACGGT
GCAGGCCTACCGACGTGATCTGTTGCGTTACCAGGAATACCTTGGTTCGCGGGGGATCGGATCGTTAGCCGAAGTGACCC
GTGTCGACGTCGAGGAGTTTCGACGCCATCTGGATCACATTGGCCTGGCCCCCGCGTCTGTGACGCGTTGTGTGGTTGCA
GTACGAAATTTGCATCGTTTCGCAGTGGGGTCTGGGCAACTCCAGGCCGATGTCACCGCTGGGATGTCCCCAGGAACCCG
TTCCCGTCGGCTCCCGAAAGCCTTGTCGATGGATCAAGTTGAGTCCTTGCTCGCTGCACCAGACACCAGTACGGTCGAGG
GGCTACGGGACGCTGCCCTGCTGGAGCTGCTCTACGGTACGGGGGCGCGAGTTTCGGAGGTCTGTGCTCTTGACGTTGAC
GACATCCGTCCCGTGTTGGATGACCCTGACCTCGGTTTGAGGCTCATCGGCAAGGGGGATAAGGAGCGCATCGTTCCGCT
GGGTAGCTACGCCGCTAAAGCTGTAGATGCCTGGTTAATAAGGGGACGTCCTGCATGGGCTGAGATTGGCAACGGGGAAC
ATGCCCTACTGCTCAATACCCGCGGTCGGCGGCTGTCCCGACAGTCAGCGTGGGCTGTCATTCGTCGTGCCGGTGAGGCT
GCCGGGCTCGACGTTGAGCACCTATCCCCGCACAGTCTTCGACACTCCTACGCCACCCACCTACTGGACGGTGGTGCCGA
TGTTCGTGTCGTGCAGGAGCTACTGGGGCATTCGTCCGTGACGACGACCCAGATCTACACCCTCGTGACGGCCGATCACC
TGAGGGAGGTCTACCGCTCGTCGCACCCTCGCGCCGTCTAG

Upstream 100 bases:

>100_bases
AACTGGCTCGTCGCACTGATCGAGTTAACGAGCTGCGTCCCGCTCATGCGCCGTGGCCGATTCGGGAGCGTCCTGGTGGT
ATTGACGGAGTTCGCGCAGA

Downstream 100 bases:

>100_bases
GCTCAGCATTGCGGGTGGGTGTGGTTGTCGGTTGTGCCCACTATCGTTAGGAAGAGCAATATTGCCGCGACGTCGAGAGG
AAGGTCACTACGTGTCCGAG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTSLVGGQAEDYLRHLVVERGLSDNTVQAYRRDLLRYQEYLGSRGIGSLAEVTRVDVEEFRRHLDHIGLAPASVTRCVVA
VRNLHRFAVGSGQLQADVTAGMSPGTRSRRLPKALSMDQVESLLAAPDTSTVEGLRDAALLELLYGTGARVSEVCALDVD
DIRPVLDDPDLGLRLIGKGDKERIVPLGSYAAKAVDAWLIRGRPAWAEIGNGEHALLLNTRGRRLSRQSAWAVIRRAGEA
AGLDVEHLSPHSLRHSYATHLLDGGADVRVVQELLGHSSVTTTQIYTLVTADHLREVYRSSHPRAV

Sequences:

>Translated_306_residues
MTSLVGGQAEDYLRHLVVERGLSDNTVQAYRRDLLRYQEYLGSRGIGSLAEVTRVDVEEFRRHLDHIGLAPASVTRCVVA
VRNLHRFAVGSGQLQADVTAGMSPGTRSRRLPKALSMDQVESLLAAPDTSTVEGLRDAALLELLYGTGARVSEVCALDVD
DIRPVLDDPDLGLRLIGKGDKERIVPLGSYAAKAVDAWLIRGRPAWAEIGNGEHALLLNTRGRRLSRQSAWAVIRRAGEA
AGLDVEHLSPHSLRHSYATHLLDGGADVRVVQELLGHSSVTTTQIYTLVTADHLREVYRSSHPRAV
>Mature_305_residues
TSLVGGQAEDYLRHLVVERGLSDNTVQAYRRDLLRYQEYLGSRGIGSLAEVTRVDVEEFRRHLDHIGLAPASVTRCVVAV
RNLHRFAVGSGQLQADVTAGMSPGTRSRRLPKALSMDQVESLLAAPDTSTVEGLRDAALLELLYGTGARVSEVCALDVDD
IRPVLDDPDLGLRLIGKGDKERIVPLGSYAAKAVDAWLIRGRPAWAEIGNGEHALLLNTRGRRLSRQSAWAVIRRAGEAA
GLDVEHLSPHSLRHSYATHLLDGGADVRVVQELLGHSSVTTTQIYTLVTADHLREVYRSSHPRAV

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=42.2297297297297, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1790244, Length=297, Percent_Identity=36.3636363636364, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1790768, Length=179, Percent_Identity=32.9608938547486, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790767, Length=185, Percent_Identity=32.4324324324324, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33425; Mature: 33294

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLVGGQAEDYLRHLVVERGLSDNTVQAYRRDLLRYQEYLGSRGIGSLAEVTRVDVEEF
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RRHLDHIGLAPASVTRCVVAVRNLHRFAVGSGQLQADVTAGMSPGTRSRRLPKALSMDQV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCHHHCCCHHCCHHHH
ESLLAAPDTSTVEGLRDAALLELLYGTGARVSEVCALDVDDIRPVLDDPDLGLRLIGKGD
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHCCCCCCCCCCCEEEECCCC
KERIVPLGSYAAKAVDAWLIRGRPAWAEIGNGEHALLLNTRGRRLSRQSAWAVIRRAGEA
CCCEEECHHHHHHHHHHHHHCCCCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
AGLDVEHLSPHSLRHSYATHLLDGGADVRVVQELLGHSSVTTTQIYTLVTADHLREVYRS
CCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
SHPRAV
CCCCCC
>Mature Secondary Structure 
TSLVGGQAEDYLRHLVVERGLSDNTVQAYRRDLLRYQEYLGSRGIGSLAEVTRVDVEEF
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
RRHLDHIGLAPASVTRCVVAVRNLHRFAVGSGQLQADVTAGMSPGTRSRRLPKALSMDQV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCCCHHHCCCHHCCHHHH
ESLLAAPDTSTVEGLRDAALLELLYGTGARVSEVCALDVDDIRPVLDDPDLGLRLIGKGD
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHCCCCCCCCCCCEEEECCCC
KERIVPLGSYAAKAVDAWLIRGRPAWAEIGNGEHALLLNTRGRRLSRQSAWAVIRRAGEA
CCCEEECHHHHHHHHHHHHHCCCCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCC
AGLDVEHLSPHSLRHSYATHLLDGGADVRVVQELLGHSSVTTTQIYTLVTADHLREVYRS
CCCCHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHC
SHPRAV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]