Click here to switch to the map view.

The map label for this gene is prcA [H]

Identifier: 50842687

GI number: 50842687

Start: 1315143

End: 1315823

Strand: Direct

Name: prcA [H]

Synonym: PPA1207

Alternate gene names: 50842687

Gene position: 1315143-1315823 (Clockwise)

Preceding gene: 50842686

Following gene: 50842688

Centisome position: 51.37

GC content: 60.21

Gene sequence:

>681_bases
ATGATGACGGTTCCAGCCTATGTTCCACCGAGTGAGTGGGTAACTGATCGTTCCACGTTTGTCTCAGATTCCATTCGCAA
TGGCGGCGACGGTATCGTCGTCGCTCGATGCGCCAACGGGATCGCGTTGTTAGCGCGTCAGTGCGGAGCCGACCTTCCTA
AGGGCATGCGATCGGTCTCTGAAATCCACGATCGTCTAGCCTTCGCAGCCGTCGGTCTGTTTCACGAGGCAGACGAACTC
CGAGTGGCCGGTATCCGCTTTGCCGACCTGCGCGCCTACGCCTACGGCCGCCTCGACGTCACCGGACGCAGCCTGGCCAG
TATGTATGCGCGAATTATTGGCAAGACGTTTGCCCGCATCGACGTTAAGCCTTATCAAGTCCAGGTCACGGTCGCCGAGC
TTGGCTTGGTCCCCTCGGAGGATCGCTTTTACACGATTGATTTCGACGGTTCTGTACGTGCCGGCACAGGCCCCATCCTG
ATGGGTGCAACCGGTGAGAACTCCCTCGACCTGCCCAATAACGCGCCGGTATCCGAGGTCGTGCGAGCTGCGGCACATGT
CCTTGACGTTGAGCCCGCGAACCTTGAGGTGGGTTTGCTTAACCGCCACGCCTCGACGCGTCGTCACTTCCGACGTCTCG
ACGCCGCGACCGTGTTGGAGGCCGACGGTGACGGATCCTAA

Upstream 100 bases:

>100_bases
ATTCCCATGGCGTGACCCGAATGCCCACCGAGGAGGTGGCGGTACTGACGAAACGGCTAGTCGACCAGGTCACCGCCGAA
TCTGATCGTGAGGAGGCCCA

Downstream 100 bases:

>100_bases
TCGCGTCGAGCCGACGTTAACCGGACCGGTCCTTATCGTTGGTGTCGGCCTTATTGGGGCATCCATCGGTAAGGCCCTGA
TGCGGGAGGGAACCGATGTT

Product: 20S proteasome alpha-subunit

Products: NA

Alternate protein names: 20S proteasome alpha subunit; Proteasome core protein PrcA [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MMTVPAYVPPSEWVTDRSTFVSDSIRNGGDGIVVARCANGIALLARQCGADLPKGMRSVSEIHDRLAFAAVGLFHEADEL
RVAGIRFADLRAYAYGRLDVTGRSLASMYARIIGKTFARIDVKPYQVQVTVAELGLVPSEDRFYTIDFDGSVRAGTGPIL
MGATGENSLDLPNNAPVSEVVRAAAHVLDVEPANLEVGLLNRHASTRRHFRRLDAATVLEADGDGS

Sequences:

>Translated_226_residues
MMTVPAYVPPSEWVTDRSTFVSDSIRNGGDGIVVARCANGIALLARQCGADLPKGMRSVSEIHDRLAFAAVGLFHEADEL
RVAGIRFADLRAYAYGRLDVTGRSLASMYARIIGKTFARIDVKPYQVQVTVAELGLVPSEDRFYTIDFDGSVRAGTGPIL
MGATGENSLDLPNNAPVSEVVRAAAHVLDVEPANLEVGLLNRHASTRRHFRRLDAATVLEADGDGS
>Mature_226_residues
MMTVPAYVPPSEWVTDRSTFVSDSIRNGGDGIVVARCANGIALLARQCGADLPKGMRSVSEIHDRLAFAAVGLFHEADEL
RVAGIRFADLRAYAYGRLDVTGRSLASMYARIIGKTFARIDVKPYQVQVTVAELGLVPSEDRFYTIDFDGSVRAGTGPIL
MGATGENSLDLPNNAPVSEVVRAAAHVLDVEPANLEVGLLNRHASTRRHFRRLDAATVLEADGDGS

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation [H]

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022296
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: =3.4.25.1 [H]

Molecular weight: Translated: 24313; Mature: 24313

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTVPAYVPPSEWVTDRSTFVSDSIRNGGDGIVVARCANGIALLARQCGADLPKGMRSVS
CCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHH
EIHDRLAFAAVGLFHEADELRVAGIRFADLRAYAYGRLDVTGRSLASMYARIIGKTFARI
HHHHHHHHHHHHHHHCCCCEEEECEEEEHHHEEEEEEEEECHHHHHHHHHHHHHHHHHEE
DVKPYQVQVTVAELGLVPSEDRFYTIDFDGSVRAGTGPILMGATGENSLDLPNNAPVSEV
CCCEEEEEEEHHHHCCCCCCCCEEEEECCCCEECCCCCEEEECCCCCCCCCCCCCCHHHH
VRAAAHVLDVEPANLEVGLLNRHASTRRHFRRLDAATVLEADGDGS
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCHHEEEECCCCCC
>Mature Secondary Structure
MMTVPAYVPPSEWVTDRSTFVSDSIRNGGDGIVVARCANGIALLARQCGADLPKGMRSVS
CCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCHHHHHHHH
EIHDRLAFAAVGLFHEADELRVAGIRFADLRAYAYGRLDVTGRSLASMYARIIGKTFARI
HHHHHHHHHHHHHHHCCCCEEEECEEEEHHHEEEEEEEEECHHHHHHHHHHHHHHHHHEE
DVKPYQVQVTVAELGLVPSEDRFYTIDFDGSVRAGTGPILMGATGENSLDLPNNAPVSEV
CCCEEEEEEEHHHHCCCCCCCCEEEEECCCCEECCCCCEEEECCCCCCCCCCCCCCHHHH
VRAAAHVLDVEPANLEVGLLNRHASTRRHFRRLDAATVLEADGDGS
HHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCHHEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA