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The map label for this gene is menB [H]

Identifier: 50842391

GI number: 50842391

Start: 988821

End: 989810

Strand: Reverse

Name: menB [H]

Synonym: PPA0907

Alternate gene names: 50842391

Gene position: 989810-988821 (Counterclockwise)

Preceding gene: 50842392

Following gene: 50842390

Centisome position: 38.66

GC content: 63.03

Gene sequence:

>990_bases
GTGAGCACCCTTCCTTTCGTTTCTGACACTTTTGATGCAGCCCGCTGGCGCGATGTTGACCTTCCCGGGGCTCCGCTGAC
CGACATGACCTTCCATCGCCTCGTGTCTCGGGGCAAGTCTGACCACGCCCCGGCTGGGGAGGATCTGCCGGTGGTACGCA
TTGCCTTCGACCGCCCGGCCATCCGCAACGCCTTCCGCCCCCACACGGTTGACGAGTTGTACCGCTGTATCGACGCCGCC
CGTTGCACCCCAGATGTTGCGGCACTCATCCTCACTGGCAATGGCCCTTCCCCGCGCGACGGTGGGTACGCCTTCTGCTC
AGGCGGCGACCAGCGGATCCGCGGAGCCGCCGGATACCAGTACGAGTCGCAGGAAACCTCCGGCGACGAGGACCTGGCCA
CCGACGCCCGACGCGAACACATCGAGAAGGGACGGCTGGGACGTCTTCACATCCTTGAGGTGCAACGCCTCATGCGTGCC
ACCCCCAAACCGATCATCGCCGCCATCCCTGGATGGACAACCGGCGGCGGCCACTCCCTCATGGTGGTAGCCGATATGGC
CGTGGCCAGCCGCGAGTACGCCAGGTTTAAGCAGGTTGATGCCAACGTCGGTTCATTTGATGCCGGGTACGGTTCGGCCC
TACTGGCACGCCAGATCGGTGACAAGCGAGCCCGCGAGATCTTCTTCCTCGCCGAAACATATGACGCCGAGCAGGCCGAA
AAGTGGGGCGTCATCAACCAGGCCGTTGACCACGCTGAATTGGAGAACACCGCCATTGAGTGGGGACTGACGATCGCTGG
CAAATCCCCGCAGGCGATCCGGATGCTCAAGTATGCCTTTAATATGGTTGACGACGGCATCGCTGGTCAGCAGGCATTCG
CTGGTGAGGCGACCCGGATGGCATATATGACCGAGGAGGCCCAGGAGGGGCGTGACGCCTTCCTCGAGCACCGCTCCCCG
GACTGGTCCGACTACCCCTATTACTTCTGA

Upstream 100 bases:

>100_bases
CTCCTGGCAGGCTCACCTCGGCGGGGCGGTCGGTGGCGTCATCTCGGCGTCGCGGCTAGCTCGTCATTCCAGGTAGGCAG
GCAGTGGTAACTTCCACCGG

Downstream 100 bases:

>100_bases
GGCCGTCGTGGGATCCGAGCTGACATCGCGGGTGCGGGTGGTACGCGTCGAGCGCACGCGCGAAGACGTCGACTGGCTGG
CTGGGCGTCTGACCGAAGTG

Product: naphthoate synthase

Products: NA

Alternate protein names: DHNA-CoA synthase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSTLPFVSDTFDAARWRDVDLPGAPLTDMTFHRLVSRGKSDHAPAGEDLPVVRIAFDRPAIRNAFRPHTVDELYRCIDAA
RCTPDVAALILTGNGPSPRDGGYAFCSGGDQRIRGAAGYQYESQETSGDEDLATDARREHIEKGRLGRLHILEVQRLMRA
TPKPIIAAIPGWTTGGGHSLMVVADMAVASREYARFKQVDANVGSFDAGYGSALLARQIGDKRAREIFFLAETYDAEQAE
KWGVINQAVDHAELENTAIEWGLTIAGKSPQAIRMLKYAFNMVDDGIAGQQAFAGEATRMAYMTEEAQEGRDAFLEHRSP
DWSDYPYYF

Sequences:

>Translated_329_residues
MSTLPFVSDTFDAARWRDVDLPGAPLTDMTFHRLVSRGKSDHAPAGEDLPVVRIAFDRPAIRNAFRPHTVDELYRCIDAA
RCTPDVAALILTGNGPSPRDGGYAFCSGGDQRIRGAAGYQYESQETSGDEDLATDARREHIEKGRLGRLHILEVQRLMRA
TPKPIIAAIPGWTTGGGHSLMVVADMAVASREYARFKQVDANVGSFDAGYGSALLARQIGDKRAREIFFLAETYDAEQAE
KWGVINQAVDHAELENTAIEWGLTIAGKSPQAIRMLKYAFNMVDDGIAGQQAFAGEATRMAYMTEEAQEGRDAFLEHRSP
DWSDYPYYF
>Mature_328_residues
STLPFVSDTFDAARWRDVDLPGAPLTDMTFHRLVSRGKSDHAPAGEDLPVVRIAFDRPAIRNAFRPHTVDELYRCIDAAR
CTPDVAALILTGNGPSPRDGGYAFCSGGDQRIRGAAGYQYESQETSGDEDLATDARREHIEKGRLGRLHILEVQRLMRAT
PKPIIAAIPGWTTGGGHSLMVVADMAVASREYARFKQVDANVGSFDAGYGSALLARQIGDKRAREIFFLAETYDAEQAEK
WGVINQAVDHAELENTAIEWGLTIAGKSPQAIRMLKYAFNMVDDGIAGQQAFAGEATRMAYMTEEAQEGRDAFLEHRSPD
WSDYPYYF

Specific function: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) [H]

COG id: COG0447

COG function: function code H; Dihydroxynaphthoic acid synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=286, Percent_Identity=25.5244755244755, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI31542718, Length=175, Percent_Identity=30.8571428571429, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788597, Length=275, Percent_Identity=41.8181818181818, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1787659, Length=281, Percent_Identity=25.6227758007117, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082183, Length=177, Percent_Identity=29.3785310734463, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787660, Length=274, Percent_Identity=27.3722627737226, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI221142681, Length=166, Percent_Identity=29.5180722891566, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=237, Percent_Identity=27.4261603375527, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=282, Percent_Identity=25.886524822695, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=253, Percent_Identity=30.0395256916996, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20129971, Length=287, Percent_Identity=26.1324041811847, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24653477, Length=287, Percent_Identity=26.1324041811847, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24653139, Length=278, Percent_Identity=23.021582733813, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR010198 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.3.36 [H]

Molecular weight: Translated: 36313; Mature: 36182

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLPFVSDTFDAARWRDVDLPGAPLTDMTFHRLVSRGKSDHAPAGEDLPVVRIAFDRPA
CCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHH
IRNAFRPHTVDELYRCIDAARCTPDVAALILTGNGPSPRDGGYAFCSGGDQRIRGAAGYQ
HHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCCCHHHCCCCCCC
YESQETSGDEDLATDARREHIEKGRLGRLHILEVQRLMRATPKPIIAAIPGWTTGGGHSL
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCEE
MVVADMAVASREYARFKQVDANVGSFDAGYGSALLARQIGDKRAREIFFLAETYDAEQAE
EEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHEEEEEEECCCHHHHH
KWGVINQAVDHAELENTAIEWGLTIAGKSPQAIRMLKYAFNMVDDGIAGQQAFAGEATRM
HCCHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHH
AYMTEEAQEGRDAFLEHRSPDWSDYPYYF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
STLPFVSDTFDAARWRDVDLPGAPLTDMTFHRLVSRGKSDHAPAGEDLPVVRIAFDRPA
CCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCHH
IRNAFRPHTVDELYRCIDAARCTPDVAALILTGNGPSPRDGGYAFCSGGDQRIRGAAGYQ
HHHCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCCCHHHCCCCCCC
YESQETSGDEDLATDARREHIEKGRLGRLHILEVQRLMRATPKPIIAAIPGWTTGGGHSL
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCEE
MVVADMAVASREYARFKQVDANVGSFDAGYGSALLARQIGDKRAREIFFLAETYDAEQAE
EEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHEEEEEEECCCHHHHH
KWGVINQAVDHAELENTAIEWGLTIAGKSPQAIRMLKYAFNMVDDGIAGQQAFAGEATRM
HCCHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHH
AYMTEEAQEGRDAFLEHRSPDWSDYPYYF
HHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA