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The map label for this gene is 50842392

Identifier: 50842392

GI number: 50842392

Start: 989835

End: 990587

Strand: Reverse

Name: 50842392

Synonym: PPA0908

Alternate gene names: NA

Gene position: 990587-989835 (Counterclockwise)

Preceding gene: 50842398

Following gene: 50842391

Centisome position: 38.69

GC content: 59.5

Gene sequence:

>753_bases
TTGTCATACGGTCCTCCTCGACCTTCCGACGCTGTTGCGACATCCGACATGTTGGGAACAGTGGAACCACGCCAATGCGC
CTTATGTGAAGAAAATCACATAAGTTCTTTGATTCTTCTTTGCCACACTGGGTACATGACTTCCTATCTGCCCCCGTCGT
CCGCTCCTGTCCGCCGGCGTCAGGCCTCACCGCCGATCCGCACCAATTCCATCGCGAGCAGCGCAGGTGTGATGGCCGTC
GTCGTCGCGATCATGTGGATCCTCGAGGTCATCGACACCATGCTTGGCAACACTCTTGACCACTTCGGCATCCATTCCTG
GACCGGGCAGGGGCTGTGGGAAATCTTCACTGCCCCATGGCTGCACTACGGTTGGGCACATCTGGCCGGCAATTCCGTGC
CGCTGTTTGTCCTAGGAATGCTCGTGTACCTGGAGTCGACACGAACCTGGATCGTCTCAGGGCTGACGATCATGGTGTGC
TCGGGACTTTTCGCGTGGTGTTTCAGCGCTCCCGGAACGATCACCCTGGGGGCGTCCGGGATCGTTTTCGGTTGGTTGGC
CTATCTGCTGGTCCGCGGCCTGTTCACCAAGAGACTGCACGACATCCTGATAGCGATCATCGTATTCCTCATCTACGGAT
CAGTGCTGTGGGGAGTGCTGCCGGGCGCGGCAGGTGTCTCCTGGCAGGCTCACCTCGGCGGGGCGGTCGGTGGCGTCATC
TCGGCGTCGCGGCTAGCTCGTCATTCCAGGTAG

Upstream 100 bases:

>100_bases
CGCGATTGGTCGGCCCTTACCTTGCCCTCAAGCGTCTTCCAGTCTGAGACCCAGGCGTTGTCGACGATGTTCTGATCAGG
TTCGAAGAGGTCCTGCTGGT

Downstream 100 bases:

>100_bases
GCAGGCAGTGGTAACTTCCACCGGGTGAGCACCCTTCCTTTCGTTTCTGACACTTTTGATGCAGCCCGCTGGCGCGATGT
TGACCTTCCCGGGGCTCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSYGPPRPSDAVATSDMLGTVEPRQCALCEENHISSLILLCHTGYMTSYLPPSSAPVRRRQASPPIRTNSIASSAGVMAV
VVAIMWILEVIDTMLGNTLDHFGIHSWTGQGLWEIFTAPWLHYGWAHLAGNSVPLFVLGMLVYLESTRTWIVSGLTIMVC
SGLFAWCFSAPGTITLGASGIVFGWLAYLLVRGLFTKRLHDILIAIIVFLIYGSVLWGVLPGAAGVSWQAHLGGAVGGVI
SASRLARHSR

Sequences:

>Translated_250_residues
MSYGPPRPSDAVATSDMLGTVEPRQCALCEENHISSLILLCHTGYMTSYLPPSSAPVRRRQASPPIRTNSIASSAGVMAV
VVAIMWILEVIDTMLGNTLDHFGIHSWTGQGLWEIFTAPWLHYGWAHLAGNSVPLFVLGMLVYLESTRTWIVSGLTIMVC
SGLFAWCFSAPGTITLGASGIVFGWLAYLLVRGLFTKRLHDILIAIIVFLIYGSVLWGVLPGAAGVSWQAHLGGAVGGVI
SASRLARHSR
>Mature_249_residues
SYGPPRPSDAVATSDMLGTVEPRQCALCEENHISSLILLCHTGYMTSYLPPSSAPVRRRQASPPIRTNSIASSAGVMAVV
VAIMWILEVIDTMLGNTLDHFGIHSWTGQGLWEIFTAPWLHYGWAHLAGNSVPLFVLGMLVYLESTRTWIVSGLTIMVCS
GLFAWCFSAPGTITLGASGIVFGWLAYLLVRGLFTKRLHDILIAIIVFLIYGSVLWGVLPGAAGVSWQAHLGGAVGGVIS
ASRLARHSR

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 26935; Mature: 26804

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYGPPRPSDAVATSDMLGTVEPRQCALCEENHISSLILLCHTGYMTSYLPPSSAPVRRR
CCCCCCCCCCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QASPPIRTNSIASSAGVMAVVVAIMWILEVIDTMLGNTLDHFGIHSWTGQGLWEIFTAPW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHH
LHYGWAHLAGNSVPLFVLGMLVYLESTRTWIVSGLTIMVCSGLFAWCFSAPGTITLGASG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHH
IVFGWLAYLLVRGLFTKRLHDILIAIIVFLIYGSVLWGVLPGAAGVSWQAHLGGAVGGVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHH
SASRLARHSR
HHHHHHHCCC
>Mature Secondary Structure 
SYGPPRPSDAVATSDMLGTVEPRQCALCEENHISSLILLCHTGYMTSYLPPSSAPVRRR
CCCCCCCCCHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QASPPIRTNSIASSAGVMAVVVAIMWILEVIDTMLGNTLDHFGIHSWTGQGLWEIFTAPW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHH
LHYGWAHLAGNSVPLFVLGMLVYLESTRTWIVSGLTIMVCSGLFAWCFSAPGTITLGASG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHH
IVFGWLAYLLVRGLFTKRLHDILIAIIVFLIYGSVLWGVLPGAAGVSWQAHLGGAVGGVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHH
SASRLARHSR
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]