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The map label for this gene is ctaD1 [H]

Identifier: 50842190

GI number: 50842190

Start: 772544

End: 774262

Strand: Direct

Name: ctaD1 [H]

Synonym: PPA0702

Alternate gene names: 50842190

Gene position: 772544-774262 (Clockwise)

Preceding gene: 50842189

Following gene: 50842191

Centisome position: 30.17

GC content: 58.12

Gene sequence:

>1719_bases
GTGACCAGCGCATCCATTGCTCAGCGGACCGCACCTCCTGCCATTACTCGCCAGGAGCGTCGCAAGGCCAGCTTTGGTGC
CCTCGTTTGGGATTACATGACGACCACCGACCATAAGAAAATCGGCCGGCTGTACTTTGGTACGTCGCTGTTTTTCTTCG
TCTTTGGCGGCATCCTTGCCCTGCTTATTCGCGCCGAGTTGGCATATCCAGGTATGCAGTTTATGCACCAGGAGACCTTC
AACCAGCTCTTCACGATGCACGGCACGATCATGCTGCTGATGTTTGCCACCCCGCTGTTTTCCGGGTTCGCGAACTTCTT
CATGCCGCTTCAGATCGGTGCCCCGGATGTCGCGTTCCCGCGTATTAACCAGTTTGCGTACTGGCTGTACCTTTTCGGCT
CCCTGATGGCCTGTAGCGGCTTCCTCACCCCTGGTGGTGCTGCCAGCTTTGGTTGGTTCGCCTACGCGCCGCTATCGGAC
GCCATCAACTCACCGGGAGTCGGCGGGGACCTGTGGGTGATGGGCCTGTACCTCCTTGGCTTGTCGTCCATCCTCGGTGC
TGTCAACTTTGTGACGACGATCATTCTCATGCGTACCCCCGGCATGACGATGTTCCGGATGCCGATTTTCTCCTGGAATA
TCCTCATCACCTCGATCATGGTGCTGGTCGTCTTCCCAGTCCTGTCGGCTGGTCTGCTCGTTCTCGAGGCTGATCGGGCT
CTGGGAGCCCATATCTTCGACGCTGCGAATGGTGGCCCGATCCTGTGGCAGCACCTCTTCTGGTTCTTCGGGCACCCGGA
GGTGTACGTCATCGCCTTGCCGTTCTTTGGCATCATCACTGAGGTGCTGCCAGTGTTCAGTCGCAAGCCGGTGTTTGGCT
ATGTCGGCCTGGTATTCGCGACCCTGGCTATCGGTGGTCTGTCGGTGTCTGTGTGGGCCCACCACATGTTCGTGACTGGC
GCGGTCTCCCTGCCGTTCTTCTCCTTCATGACCTTCACGATCGCTGTTCCGACTGGTGTGAAGTTTTTCAACTGGATTGG
CACCATGTGGGGTGGCTCGTTGAGCTTTGACACGCCGATGCTCTTTGCTATCGGCTTCTTGACGACCTTCCTGTTCGGCG
GTCTCACTGGTGTCATGCTCGCTAGCCCGCCGATGGACTTCAACGTGTCTGACACCTACTTCGTGGTAGCCCATTTCCAC
TATGTGCTGTTCGGCACAGTGGTCTTCGCGATGTTCGCCGGGTTCTACTATTGGTGGCCGAAGATCACTGGGCACATGCT
TAACGAGACCTGGGGCAAGATCCACTTCTGGACTCTGTTCGTCGGTTTCCACACCACCTTCCTCGTTCAGCACTGGCTTG
GTGTTGAGGGTATGCAGCGTCGTATTGCCGACTACGGTGCATGGGAGGGATTCACCTTACTCAACCAGGTGTCGACCTTC
GGCGCCTTCCTGCTGGCCATTTCGATGCTGCCGTTCGCATGGAACGTCTGGATTACTCGTCACGATCCGAATATCGAGGT
CGCTGACCCGTGGGGTTGGGGCCGTACCCTCGAGTGGGCTACTTCATGCCCGCCGCCCGCCCACAATTTCACGAAGATGA
TCCGCGTGCGCTCCACCTCTCCGGCCTTCGACATCAATCATCCGGAGGCCGCTCTGGCCCCCGAGACTGGGGAAGCTAAT
CCGCGCGAACTCGTCCACTCCGGTAAGGAGGATGCCTGA

Upstream 100 bases:

>100_bases
ACCTTCAGCAGCTCAAAGCTCAGGGCGACACCGGTGAGATCAAGCCTGCGAACTCGGTTGCTGCCCTCACCACCACCGAA
TCAAATGAGGGGGAGAAGAA

Downstream 100 bases:

>100_bases
TGAAACCGGAACGTTGGGTATTTGGCGGGCTCGGCCTGTTCTACCTCGTCGTTACCCCGGTGTACTGGTTCACGGCACAC
GAAGTGGCCGGCACTTGGGT

Product: cytochrome c oxidase polypeptide I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1-alpha; Cytochrome c oxidase polypeptide I-alpha [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MTSASIAQRTAPPAITRQERRKASFGALVWDYMTTTDHKKIGRLYFGTSLFFFVFGGILALLIRAELAYPGMQFMHQETF
NQLFTMHGTIMLLMFATPLFSGFANFFMPLQIGAPDVAFPRINQFAYWLYLFGSLMACSGFLTPGGAASFGWFAYAPLSD
AINSPGVGGDLWVMGLYLLGLSSILGAVNFVTTIILMRTPGMTMFRMPIFSWNILITSIMVLVVFPVLSAGLLVLEADRA
LGAHIFDAANGGPILWQHLFWFFGHPEVYVIALPFFGIITEVLPVFSRKPVFGYVGLVFATLAIGGLSVSVWAHHMFVTG
AVSLPFFSFMTFTIAVPTGVKFFNWIGTMWGGSLSFDTPMLFAIGFLTTFLFGGLTGVMLASPPMDFNVSDTYFVVAHFH
YVLFGTVVFAMFAGFYYWWPKITGHMLNETWGKIHFWTLFVGFHTTFLVQHWLGVEGMQRRIADYGAWEGFTLLNQVSTF
GAFLLAISMLPFAWNVWITRHDPNIEVADPWGWGRTLEWATSCPPPAHNFTKMIRVRSTSPAFDINHPEAALAPETGEAN
PRELVHSGKEDA

Sequences:

>Translated_572_residues
MTSASIAQRTAPPAITRQERRKASFGALVWDYMTTTDHKKIGRLYFGTSLFFFVFGGILALLIRAELAYPGMQFMHQETF
NQLFTMHGTIMLLMFATPLFSGFANFFMPLQIGAPDVAFPRINQFAYWLYLFGSLMACSGFLTPGGAASFGWFAYAPLSD
AINSPGVGGDLWVMGLYLLGLSSILGAVNFVTTIILMRTPGMTMFRMPIFSWNILITSIMVLVVFPVLSAGLLVLEADRA
LGAHIFDAANGGPILWQHLFWFFGHPEVYVIALPFFGIITEVLPVFSRKPVFGYVGLVFATLAIGGLSVSVWAHHMFVTG
AVSLPFFSFMTFTIAVPTGVKFFNWIGTMWGGSLSFDTPMLFAIGFLTTFLFGGLTGVMLASPPMDFNVSDTYFVVAHFH
YVLFGTVVFAMFAGFYYWWPKITGHMLNETWGKIHFWTLFVGFHTTFLVQHWLGVEGMQRRIADYGAWEGFTLLNQVSTF
GAFLLAISMLPFAWNVWITRHDPNIEVADPWGWGRTLEWATSCPPPAHNFTKMIRVRSTSPAFDINHPEAALAPETGEAN
PRELVHSGKEDA
>Mature_571_residues
TSASIAQRTAPPAITRQERRKASFGALVWDYMTTTDHKKIGRLYFGTSLFFFVFGGILALLIRAELAYPGMQFMHQETFN
QLFTMHGTIMLLMFATPLFSGFANFFMPLQIGAPDVAFPRINQFAYWLYLFGSLMACSGFLTPGGAASFGWFAYAPLSDA
INSPGVGGDLWVMGLYLLGLSSILGAVNFVTTIILMRTPGMTMFRMPIFSWNILITSIMVLVVFPVLSAGLLVLEADRAL
GAHIFDAANGGPILWQHLFWFFGHPEVYVIALPFFGIITEVLPVFSRKPVFGYVGLVFATLAIGGLSVSVWAHHMFVTGA
VSLPFFSFMTFTIAVPTGVKFFNWIGTMWGGSLSFDTPMLFAIGFLTTFLFGGLTGVMLASPPMDFNVSDTYFVVAHFHY
VLFGTVVFAMFAGFYYWWPKITGHMLNETWGKIHFWTLFVGFHTTFLVQHWLGVEGMQRRIADYGAWEGFTLLNQVSTFG
AFLLAISMLPFAWNVWITRHDPNIEVADPWGWGRTLEWATSCPPPAHNFTKMIRVRSTSPAFDINHPEAALAPETGEANP
RELVHSGKEDA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=510, Percent_Identity=42.5490196078431, Blast_Score=381, Evalue=1e-106,
Organism=Escherichia coli, GI1786634, Length=538, Percent_Identity=41.635687732342, Blast_Score=395, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6226519, Length=473, Percent_Identity=44.1860465116279, Blast_Score=381, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6226524, Length=325, Percent_Identity=43.3846153846154, Blast_Score=256, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6226523, Length=251, Percent_Identity=41.4342629482072, Blast_Score=167, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 63718; Mature: 63587

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSASIAQRTAPPAITRQERRKASFGALVWDYMTTTDHKKIGRLYFGTSLFFFVFGGILA
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLIRAELAYPGMQFMHQETFNQLFTMHGTIMLLMFATPLFSGFANFFMPLQIGAPDVAFP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCC
RINQFAYWLYLFGSLMACSGFLTPGGAASFGWFAYAPLSDAINSPGVGGDLWVMGLYLLG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHCCCCCCCHHHHHHHHHHHH
LSSILGAVNFVTTIILMRTPGMTMFRMPIFSWNILITSIMVLVVFPVLSAGLLVLEADRA
HHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHH
LGAHIFDAANGGPILWQHLFWFFGHPEVYVIALPFFGIITEVLPVFSRKPVFGYVGLVFA
HCCHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHH
TLAIGGLSVSVWAHHMFVTGAVSLPFFSFMTFTIAVPTGVKFFNWIGTMWGGSLSFDTPM
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHH
LFAIGFLTTFLFGGLTGVMLASPPMDFNVSDTYFVVAHFHYVLFGTVVFAMFAGFYYWWP
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KITGHMLNETWGKIHFWTLFVGFHTTFLVQHWLGVEGMQRRIADYGAWEGFTLLNQVSTF
HHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHH
GAFLLAISMLPFAWNVWITRHDPNIEVADPWGWGRTLEWATSCPPPAHNFTKMIRVRSTS
HHHHHHHHHHCCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHEEECCC
PAFDINHPEAALAPETGEANPRELVHSGKEDA
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCC
>Mature Secondary Structure 
TSASIAQRTAPPAITRQERRKASFGALVWDYMTTTDHKKIGRLYFGTSLFFFVFGGILA
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LLIRAELAYPGMQFMHQETFNQLFTMHGTIMLLMFATPLFSGFANFFMPLQIGAPDVAFP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCC
RINQFAYWLYLFGSLMACSGFLTPGGAASFGWFAYAPLSDAINSPGVGGDLWVMGLYLLG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHCCCCCCCHHHHHHHHHHHH
LSSILGAVNFVTTIILMRTPGMTMFRMPIFSWNILITSIMVLVVFPVLSAGLLVLEADRA
HHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHH
LGAHIFDAANGGPILWQHLFWFFGHPEVYVIALPFFGIITEVLPVFSRKPVFGYVGLVFA
HCCHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHH
TLAIGGLSVSVWAHHMFVTGAVSLPFFSFMTFTIAVPTGVKFFNWIGTMWGGSLSFDTPM
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHH
LFAIGFLTTFLFGGLTGVMLASPPMDFNVSDTYFVVAHFHYVLFGTVVFAMFAGFYYWWP
HHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KITGHMLNETWGKIHFWTLFVGFHTTFLVQHWLGVEGMQRRIADYGAWEGFTLLNQVSTF
HHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHH
GAFLLAISMLPFAWNVWITRHDPNIEVADPWGWGRTLEWATSCPPPAHNFTKMIRVRSTS
HHHHHHHHHHCCEEEEEEEECCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHEEECCC
PAFDINHPEAALAPETGEANPRELVHSGKEDA
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]