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The map label for this gene is ctaC [H]

Identifier: 50842189

GI number: 50842189

Start: 771639

End: 772547

Strand: Direct

Name: ctaC [H]

Synonym: PPA0701

Alternate gene names: 50842189

Gene position: 771639-772547 (Clockwise)

Preceding gene: 50842188

Following gene: 50842190

Centisome position: 30.14

GC content: 57.87

Gene sequence:

>909_bases
GTGGGACGCAGAGTCAGCTGGCGACACGACCTTGACCCGAACGTGCCCCGAAGTGGCAGGCGTGCTGCCGGAAAAGTCGG
CGGCGTCTGTGCCGCAGCGATAGCGGTGGTGCCCCTCAGCGGCTGCGGCAGTACTGGCCCCGGGCGCGCAGCTCGTCTCG
GTCTTGTCGATCCGGCGTCCGATCGCGCCGTGCACATGGGCAATATGTGGATTGGCGCCTGGGTTGCGGCGCTTGTCATC
GGCGTATTCGTATGGGGGCTCATCGGATTTGCCGCTTTCAAGTTCCGTCGTAAGGACGGTGACCCGGCGATTCCGCGCCA
GTCTCGGTATCACCTTCCGCTTGAAGTGCTCTACACCATCGTTCCTTTCCTTGTGATCGGCGTGCTGTTCTTCTATACCG
TTCGTACCGAGAACAAGGTGCTCGACAAGAACCCTGACCCTCAACATGTCGTTAATGTTGTCGGCCAGAAGTGGTCGTGG
ACTTTTAACTATATGGAGGCCAACAATCCTGACGCCGGTGGTGTTGTCACCCATGAGGTTGGCACTATCGAGAAGATTCC
GAATCTGTACCTTCCGGTGAGCCAGTCAGTGCGCTTCCGCCTCAAGTCCGCTGATGTTATCCACTCGTTCTGGGTGCCGG
CCTTCTACTTCAAGATGGACGTCATTCCGGGCCATCCTAACCAGTTTGACCTCACTCCGACGAGGATCGGTGTTTACGAC
GGTAAGTGCGCCGAGCTGTGTGGTACCTATCACGCAAATATGATCTTCAAGGTGCACGTGGTGTCGGTCGAGGACTACAA
CAAGCACCTTCAGCAGCTCAAAGCTCAGGGCGACACCGGTGAGATCAAGCCTGCGAACTCGGTTGCTGCCCTCACCACCA
CCGAATCAAATGAGGGGGAGAAGAAGTGA

Upstream 100 bases:

>100_bases
CGAAGCGCCTTATTTTCGCTATTGTTCAATGTGACGGACACAACAGTTACCTGTTCCCATCGTCGGGTCGGGGGCGGGCT
TGCAATGGGGAGGGTGAACC

Downstream 100 bases:

>100_bases
CCAGCGCATCCATTGCTCAGCGGACCGCACCTCCTGCCATTACTCGCCAGGAGCGTCGCAAGGCCAGCTTTGGTGCCCTC
GTTTGGGATTACATGACGAC

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MGRRVSWRHDLDPNVPRSGRRAAGKVGGVCAAAIAVVPLSGCGSTGPGRAARLGLVDPASDRAVHMGNMWIGAWVAALVI
GVFVWGLIGFAAFKFRRKDGDPAIPRQSRYHLPLEVLYTIVPFLVIGVLFFYTVRTENKVLDKNPDPQHVVNVVGQKWSW
TFNYMEANNPDAGGVVTHEVGTIEKIPNLYLPVSQSVRFRLKSADVIHSFWVPAFYFKMDVIPGHPNQFDLTPTRIGVYD
GKCAELCGTYHANMIFKVHVVSVEDYNKHLQQLKAQGDTGEIKPANSVAALTTTESNEGEKK

Sequences:

>Translated_302_residues
MGRRVSWRHDLDPNVPRSGRRAAGKVGGVCAAAIAVVPLSGCGSTGPGRAARLGLVDPASDRAVHMGNMWIGAWVAALVI
GVFVWGLIGFAAFKFRRKDGDPAIPRQSRYHLPLEVLYTIVPFLVIGVLFFYTVRTENKVLDKNPDPQHVVNVVGQKWSW
TFNYMEANNPDAGGVVTHEVGTIEKIPNLYLPVSQSVRFRLKSADVIHSFWVPAFYFKMDVIPGHPNQFDLTPTRIGVYD
GKCAELCGTYHANMIFKVHVVSVEDYNKHLQQLKAQGDTGEIKPANSVAALTTTESNEGEKK
>Mature_301_residues
GRRVSWRHDLDPNVPRSGRRAAGKVGGVCAAAIAVVPLSGCGSTGPGRAARLGLVDPASDRAVHMGNMWIGAWVAALVIG
VFVWGLIGFAAFKFRRKDGDPAIPRQSRYHLPLEVLYTIVPFLVIGVLFFYTVRTENKVLDKNPDPQHVVNVVGQKWSWT
FNYMEANNPDAGGVVTHEVGTIEKIPNLYLPVSQSVRFRLKSADVIHSFWVPAFYFKMDVIPGHPNQFDLTPTRIGVYDG
KCAELCGTYHANMIFKVHVVSVEDYNKHLQQLKAQGDTGEIKPANSVAALTTTESNEGEKK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=166, Percent_Identity=28.9156626506024, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6226540, Length=172, Percent_Identity=30.2325581395349, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 33239; Mature: 33107

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRVSWRHDLDPNVPRSGRRAAGKVGGVCAAAIAVVPLSGCGSTGPGRAARLGLVDPAS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC
DRAVHMGNMWIGAWVAALVIGVFVWGLIGFAAFKFRRKDGDPAIPRQSRYHLPLEVLYTI
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
VPFLVIGVLFFYTVRTENKVLDKNPDPQHVVNVVGQKWSWTFNYMEANNPDAGGVVTHEV
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEECC
GTIEKIPNLYLPVSQSVRFRLKSADVIHSFWVPAFYFKMDVIPGHPNQFDLTPTRIGVYD
CCHHHCCCEEECCCCCCEEEEHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCEEECCC
GKCAELCGTYHANMIFKVHVVSVEDYNKHLQQLKAQGDTGEIKPANSVAALTTTESNEGE
CHHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
KK
CC
>Mature Secondary Structure 
GRRVSWRHDLDPNVPRSGRRAAGKVGGVCAAAIAVVPLSGCGSTGPGRAARLGLVDPAS
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCC
DRAVHMGNMWIGAWVAALVIGVFVWGLIGFAAFKFRRKDGDPAIPRQSRYHLPLEVLYTI
CCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
VPFLVIGVLFFYTVRTENKVLDKNPDPQHVVNVVGQKWSWTFNYMEANNPDAGGVVTHEV
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEECC
GTIEKIPNLYLPVSQSVRFRLKSADVIHSFWVPAFYFKMDVIPGHPNQFDLTPTRIGVYD
CCHHHCCCEEECCCCCCEEEEHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCEEECCC
GKCAELCGTYHANMIFKVHVVSVEDYNKHLQQLKAQGDTGEIKPANSVAALTTTESNEGE
CHHHHHHHHHCCCEEEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCC
KK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]