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The map label for this gene is nanB [H]

Identifier: 50842171

GI number: 50842171

Start: 750294

End: 751985

Strand: Reverse

Name: nanB [H]

Synonym: PPA0684

Alternate gene names: 50842171

Gene position: 751985-750294 (Counterclockwise)

Preceding gene: 50842172

Following gene: 50842170

Centisome position: 29.37

GC content: 56.32

Gene sequence:

>1692_bases
ATGCACCAACGGATTTCACGCCGATCCGCATTAATCTCTGGCGGGGCAGCCTTATTCTTGAGTGTGACAGGGCAGTTCTC
TGAACACTCTCCTGCACTTGCGACACAAGAGGCAGACGTACTCGAGGTGTTCAACAGAGAGAATTCGCCATCACATTTTT
TCCGCATACCGTTCATGGTGTCTACGGCCAATGACACATTGGTCATAGGCTGCGATGCAAATCGCGCGACAACAGGCGAC
TCCGCCGACAATATCGATGCCCTGATTCGCAGAAAACCCAATGCATCCCGTTACTCAATCTCCGACGGTTGGGAAGCCCC
GTCACTGATAAAACCATTGGAGATGCGAGATTATTCGAACAAGTATGGGTACGCCCCCGCATCATCCTCCGTCATCGACG
GCGCCATCATCGAGGATTCAGTTCGACATCGACTGATGATCGTCATTGATCTCTGGGCCTGGAACGGCGGAGTATTCGAA
CACCTCAACGTCTCCCCAGATGGCCCCGTCAACGGTGGGCGCCCGCGAAAGTTCCCCCTGGGAGATGGCTTCGCCACCGT
TGCCGGACGTGACATGCTCCTGCTCTCGACGCACAACGTCACAGGGGACGCCGACGGATTGAGGGGAAATATCAATCTGA
ACATCGACCGTTCCCAATTCGACCTCGTAGCTGACCTCGACGGCCCCCGCGACAAGCACGGTCGCATTCAGATTTATGAA
TTAATCGGTATACCTCGCCCGTACACCACCGCCGGAGTCGATGACTCAAATCTCGCTCTAGGACGACGATCAAGATACTC
CTTGGACGACGGTTTCAACCTCTTCGAAGCAGGAATTCCTCTGTACGTGTTCCAGCACGGTTCAGCTCGCATCACTCCGA
TGCGCGTCTTCTACAAGGACTCGATCCTTCAGGTCTTCAACACCAATCACATCGTGGAGATCTACTCATATGACGATGGC
CGAACTTGGAACATGGGAAAACTGGTGACACGGCAGTTCAGACCCGTAGATTCTCGATACACGCTCGTCGCACCAGGTCG
GTCCATTCAAATCCGCGCAGGGGAACATGCCGGACGCATCGTCGTTCCGACTTACATGATGCTACCTGCAGGAATTTCGT
GCACCACTGTATACACCGACGATGGTGGGGAAACGTGGCAGCGGGGAACCCCGATGCCAGCCACTATCGACCTCCACGAA
AGCGCGATCACAGAGGTTCTACCCGGCGTATTGCGCAGCTTCAACCGACATTCCGCTTCTTCCGGTGGGAAGGTGCTGAC
CGCCGAGAGCGTGGATGGCGGCCATTCCTGGAGTACGCTGACTTCCGCGTTCGGCGACGACGACCAAGGCGTCGCATGCC
AAGTCTCCGCGCTCATGCTGAAGCAAACCATCGCATCACCTACGACCGGGGAACAGCTCCCTGCGCTCATTGTCGTCTCA
GCAGATGACCGCAGGCGTCGACATGGCATTGCCCATGTGGCAGTTGTCCATCGATCCTCGAGAACGTTCGGACCGCGCTC
CGAACTTGAATGGGTGAGTCACGCCGACATCACGAGCCCACAGACCCTCTTCGCCTATTCCTCGATCGCCCAGTTGTCTG
ACGGACGTGTTCTCGTGCTCTTCGAATCGTCACCTACGGACTCGTGGGCGGACGGGCTCCAACGTATGTACCTGCAGGAA
CTGGCGTCCTGA

Upstream 100 bases:

>100_bases
CCACTTCGCGCAGCACGCTGGAGTGATTCACACAGCAACACCAGATATCGCCCATTCAATGTAATCACGCTACGGAAGAC
TTAACGTTTAGGGATTCAGC

Downstream 100 bases:

>100_bases
CACCATATCGATGGGCACCAGCATCGGCCATGCTCTACCGGCATGAAGGCCCCGTGTCGTTTTTGGACTCCAGTCCTTCC
TTGCCTCACCTGCGACGAGA

Product: sialidase B

Products: NA

Alternate protein names: Neuraminidase B [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MHQRISRRSALISGGAALFLSVTGQFSEHSPALATQEADVLEVFNRENSPSHFFRIPFMVSTANDTLVIGCDANRATTGD
SADNIDALIRRKPNASRYSISDGWEAPSLIKPLEMRDYSNKYGYAPASSSVIDGAIIEDSVRHRLMIVIDLWAWNGGVFE
HLNVSPDGPVNGGRPRKFPLGDGFATVAGRDMLLLSTHNVTGDADGLRGNINLNIDRSQFDLVADLDGPRDKHGRIQIYE
LIGIPRPYTTAGVDDSNLALGRRSRYSLDDGFNLFEAGIPLYVFQHGSARITPMRVFYKDSILQVFNTNHIVEIYSYDDG
RTWNMGKLVTRQFRPVDSRYTLVAPGRSIQIRAGEHAGRIVVPTYMMLPAGISCTTVYTDDGGETWQRGTPMPATIDLHE
SAITEVLPGVLRSFNRHSASSGGKVLTAESVDGGHSWSTLTSAFGDDDQGVACQVSALMLKQTIASPTTGEQLPALIVVS
ADDRRRRHGIAHVAVVHRSSRTFGPRSELEWVSHADITSPQTLFAYSSIAQLSDGRVLVLFESSPTDSWADGLQRMYLQE
LAS

Sequences:

>Translated_563_residues
MHQRISRRSALISGGAALFLSVTGQFSEHSPALATQEADVLEVFNRENSPSHFFRIPFMVSTANDTLVIGCDANRATTGD
SADNIDALIRRKPNASRYSISDGWEAPSLIKPLEMRDYSNKYGYAPASSSVIDGAIIEDSVRHRLMIVIDLWAWNGGVFE
HLNVSPDGPVNGGRPRKFPLGDGFATVAGRDMLLLSTHNVTGDADGLRGNINLNIDRSQFDLVADLDGPRDKHGRIQIYE
LIGIPRPYTTAGVDDSNLALGRRSRYSLDDGFNLFEAGIPLYVFQHGSARITPMRVFYKDSILQVFNTNHIVEIYSYDDG
RTWNMGKLVTRQFRPVDSRYTLVAPGRSIQIRAGEHAGRIVVPTYMMLPAGISCTTVYTDDGGETWQRGTPMPATIDLHE
SAITEVLPGVLRSFNRHSASSGGKVLTAESVDGGHSWSTLTSAFGDDDQGVACQVSALMLKQTIASPTTGEQLPALIVVS
ADDRRRRHGIAHVAVVHRSSRTFGPRSELEWVSHADITSPQTLFAYSSIAQLSDGRVLVLFESSPTDSWADGLQRMYLQE
LAS
>Mature_563_residues
MHQRISRRSALISGGAALFLSVTGQFSEHSPALATQEADVLEVFNRENSPSHFFRIPFMVSTANDTLVIGCDANRATTGD
SADNIDALIRRKPNASRYSISDGWEAPSLIKPLEMRDYSNKYGYAPASSSVIDGAIIEDSVRHRLMIVIDLWAWNGGVFE
HLNVSPDGPVNGGRPRKFPLGDGFATVAGRDMLLLSTHNVTGDADGLRGNINLNIDRSQFDLVADLDGPRDKHGRIQIYE
LIGIPRPYTTAGVDDSNLALGRRSRYSLDDGFNLFEAGIPLYVFQHGSARITPMRVFYKDSILQVFNTNHIVEIYSYDDG
RTWNMGKLVTRQFRPVDSRYTLVAPGRSIQIRAGEHAGRIVVPTYMMLPAGISCTTVYTDDGGETWQRGTPMPATIDLHE
SAITEVLPGVLRSFNRHSASSGGKVLTAESVDGGHSWSTLTSAFGDDDQGVACQVSALMLKQTIASPTTGEQLPALIVVS
ADDRRRRHGIAHVAVVHRSSRTFGPRSELEWVSHADITSPQTLFAYSSIAQLSDGRVLVLFESSPTDSWADGLQRMYLQE
LAS

Specific function: Unknown

COG id: COG4409

COG function: function code G; Neuraminidase (sialidase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 BNR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002860
- InterPro:   IPR008985
- InterPro:   IPR013320
- InterPro:   IPR004124
- InterPro:   IPR011040 [H]

Pfam domain/function: PF02012 BNR; PF02973 Sialidase [H]

EC number: =3.2.1.18 [H]

Molecular weight: Translated: 61684; Mature: 61684

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQRISRRSALISGGAALFLSVTGQFSEHSPALATQEADVLEVFNRENSPSHFFRIPFMV
CCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEEE
STANDTLVIGCDANRATTGDSADNIDALIRRKPNASRYSISDGWEAPSLIKPLEMRDYSN
EECCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCHHCCCHHHCCCCC
KYGYAPASSSVIDGAIIEDSVRHRLMIVIDLWAWNGGVFEHLNVSPDGPVNGGRPRKFPL
CCCCCCCCCCCCCCHHHHHCCCCEEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCC
GDGFATVAGRDMLLLSTHNVTGDADGLRGNINLNIDRSQFDLVADLDGPRDKHGRIQIYE
CCCEEEECCCEEEEEEECCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCEEEEE
LIGIPRPYTTAGVDDSNLALGRRSRYSLDDGFNLFEAGIPLYVFQHGSARITPMRVFYKD
EECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHCCCCEEEEECCCCEEEEEEEEEHH
SILQVFNTNHIVEIYSYDDGRTWNMGKLVTRQFRPVDSRYTLVAPGRSIQIRAGEHAGRI
HHHHHCCCCCEEEEEECCCCCEECHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCEE
VVPTYMMLPAGISCTTVYTDDGGETWQRGTPMPATIDLHESAITEVLPGVLRSFNRHSAS
EEEEHEECCCCCEEEEEEECCCCCHHHCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCC
SGGKVLTAESVDGGHSWSTLTSAFGDDDQGVACQVSALMLKQTIASPTTGEQLPALIVVS
CCCEEEEEECCCCCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEE
ADDRRRRHGIAHVAVVHRSSRTFGPRSELEWVSHADITSPQTLFAYSSIAQLSDGRVLVL
CCCCHHHCCCEEEEEEEECCCCCCCHHHCCCHHCCCCCCCHHHHHHHHHHHCCCCEEEEE
FESSPTDSWADGLQRMYLQELAS
EECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHQRISRRSALISGGAALFLSVTGQFSEHSPALATQEADVLEVFNRENSPSHFFRIPFMV
CCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEEEEE
STANDTLVIGCDANRATTGDSADNIDALIRRKPNASRYSISDGWEAPSLIKPLEMRDYSN
EECCCEEEEEECCCCCCCCCCCCCHHHHHHCCCCCCEEECCCCCCCCHHCCCHHHCCCCC
KYGYAPASSSVIDGAIIEDSVRHRLMIVIDLWAWNGGVFEHLNVSPDGPVNGGRPRKFPL
CCCCCCCCCCCCCCHHHHHCCCCEEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCC
GDGFATVAGRDMLLLSTHNVTGDADGLRGNINLNIDRSQFDLVADLDGPRDKHGRIQIYE
CCCEEEECCCEEEEEEECCCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCCCCEEEEE
LIGIPRPYTTAGVDDSNLALGRRSRYSLDDGFNLFEAGIPLYVFQHGSARITPMRVFYKD
EECCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHCCCCEEEEECCCCEEEEEEEEEHH
SILQVFNTNHIVEIYSYDDGRTWNMGKLVTRQFRPVDSRYTLVAPGRSIQIRAGEHAGRI
HHHHHCCCCCEEEEEECCCCCEECHHHHHHHHCCCCCCCEEEEECCCEEEEEECCCCCEE
VVPTYMMLPAGISCTTVYTDDGGETWQRGTPMPATIDLHESAITEVLPGVLRSFNRHSAS
EEEEHEECCCCCEEEEEEECCCCCHHHCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCC
SGGKVLTAESVDGGHSWSTLTSAFGDDDQGVACQVSALMLKQTIASPTTGEQLPALIVVS
CCCEEEEEECCCCCCCHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCEEEEEE
ADDRRRRHGIAHVAVVHRSSRTFGPRSELEWVSHADITSPQTLFAYSSIAQLSDGRVLVL
CCCCHHHCCCEEEEEEEECCCCCCCHHHCCCHHCCCCCCCHHHHHHHHHHHCCCCEEEEE
FESSPTDSWADGLQRMYLQELAS
EECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759848; 11463916 [H]