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The map label for this gene is dhaK [H]

Identifier: 50842109

GI number: 50842109

Start: 687293

End: 689023

Strand: Direct

Name: dhaK [H]

Synonym: PPA0622

Alternate gene names: 50842109

Gene position: 687293-689023 (Clockwise)

Preceding gene: 50842107

Following gene: 50842112

Centisome position: 26.84

GC content: 62.74

Gene sequence:

>1731_bases
ATGACCCGACTTGTGAATAATCCCGATAATTTCCCATCTCAGGCGGTCGCGGGGCTTGTCAGCGCTTTCCCGAACCATCT
GAGGCCGGTATTCGGGGGAGTTGTTCGCGCCGCCCGTACCGATCGCAAGGTTGCCCTCGTCGTCGGTGGGGGATCGGGAC
ATTACCCGGCCTTTGCAGGTTGGGTCGGTCCTGGCTTCGCTGATGGTGCTGTGTGCGGGAACATCTTCTCCTCTCCCTCG
GCCTCCCAGGCTTATGCAGTGTGCAAAGCCGCTGATCGTGGCGCCGGGCTCCTCATTGGATTCGGCAACTACGCCGGGGA
CGTCCTGCACTTTGGGCAAGCAGCAGAGCGGCTTCGTAGCGAGGGGATCGACGCGCGTTGCCTGCTCGTTACTGACGACA
TTGCTTCGGCGCCGGACCATCTCAAGCGTCGGGGAATTGCTGGCGACCTGCCGGTCTTCAAGGTCACAGCGGCGGCCTGT
GAGGAGGGCCGGGACATTGACGAGGTCGTCGCGATATTTGACCGGGTTAACGATCGCACTCGGTCCCTCGGAGTGGCCTT
TGCAGGCTGCACTTTGCCGGGAGCCGACGAGCCTCTATTCCGAGTCGAGGCAGGCCAGATGGGCGTGGGCATGGGGATCC
ACGGTGAGCCCGGCATTCACGATGAGACCTTGGGCACCGCAGACGAGGTGGCTGCCATGCTCGTTAACAGATTGCTGGCT
GACCGGCCCGAGAATCCTGGGACTCGAGTGGTGCCGATCGTTAACGGGCTGGGCAGTACTAAATACGAGGAGCTCTTCGT
ACTGTGGAATGACATCAGCCGTCATCTTGAGAAAGCTGGCCTGGCAATTGTCGATCCGCAGGTGGGAGAATTTGTCACCA
GCCTCGACATGGCCGGAGTCTCCCTGACTCTGGTGTGGCTCGACGACGTCATCGAGCCGTTGTGGTTGGCAGCATGCGAC
ACTCCCGCGTACCGACGCGGAACTGTCGGTCAGGTGGATTTTGATACCACGCCGCTGCCCCAGGAGGTTGAGCGGGTCAT
GGTTGCTAACCCGGGATCTCGAGCTTCCCGGAGTCTTGCGGGCGTTATCGTCGAAGCTCTGGAAGTGGTGGCGACGAGGT
TGTCGGAACGCAGTAGCGAGTTGGGCCGTCTCGATTCTGTGGCTGGCGACGGTGACCACGGTATTGGCATGGCACGTGGG
TCCCGGGCTGCCCTTGCTGAGGCACGACGGGTGAGCGGGGACGGTGCCGGTGCGGCAACGACTCTCAATGCGGCCGGCTC
AGCATGGTCTGAGCATGCTGGAGGGACCTCAGGTGCGTTATGGGGAGCAGTGCTGACCGCCATCGGAGCGGTACTTGGTG
ACGAGGACCCGGCAGGCGAGGACACCATCCCTCGGGCGGCTCGAGCAGCCCTCGACGCTGTTATCCGGCTGGGAGGGGCT
AGCGTCGGCGATAAAACGATGGTTGATGCCATGGACCCCTTCGTCACGACCCTCGAGTCCTCGTCTGATCCGCTGCCGCA
GGCTTGGGAATCAGCCTGTCATGCTGCCGACATGGCAGCTCAGGCGACCTCCGAGGTGACAGCCACGGTCGGTCGGGCGC
GCCCGCTGGGGGACAAGTCGCTGGGAACGCCTGATCCGGGAGCAGTGTCCTTCCACGAGGTGGTCGTCGCAGTCGGATCC
GTGCTGTCGAAGTCAGCGTTGAGCAACGGGAGGTTTCGCGCTCAACGTTGA

Upstream 100 bases:

>100_bases
CTAGTGTCGCATTTCTGTTACGTCGGGCAGGCTGCGCAGGCGCCAATTACCATGTGACATGGGGAAAACACCATCGACGA
TGATGACAGGAGACCCAGAT

Downstream 100 bases:

>100_bases
CCGACCGGAGGTTTCGCGCTCCAGGGAAACACGATCCACTTGTCCGTGGCTTTCCACACGAAGTCCGGGTTGATGACGGT
CGTGGGCTTGGCATAGAGCA

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 576; Mature: 575

Protein sequence:

>576_residues
MTRLVNNPDNFPSQAVAGLVSAFPNHLRPVFGGVVRAARTDRKVALVVGGGSGHYPAFAGWVGPGFADGAVCGNIFSSPS
ASQAYAVCKAADRGAGLLIGFGNYAGDVLHFGQAAERLRSEGIDARCLLVTDDIASAPDHLKRRGIAGDLPVFKVTAAAC
EEGRDIDEVVAIFDRVNDRTRSLGVAFAGCTLPGADEPLFRVEAGQMGVGMGIHGEPGIHDETLGTADEVAAMLVNRLLA
DRPENPGTRVVPIVNGLGSTKYEELFVLWNDISRHLEKAGLAIVDPQVGEFVTSLDMAGVSLTLVWLDDVIEPLWLAACD
TPAYRRGTVGQVDFDTTPLPQEVERVMVANPGSRASRSLAGVIVEALEVVATRLSERSSELGRLDSVAGDGDHGIGMARG
SRAALAEARRVSGDGAGAATTLNAAGSAWSEHAGGTSGALWGAVLTAIGAVLGDEDPAGEDTIPRAARAALDAVIRLGGA
SVGDKTMVDAMDPFVTTLESSSDPLPQAWESACHAADMAAQATSEVTATVGRARPLGDKSLGTPDPGAVSFHEVVVAVGS
VLSKSALSNGRFRAQR

Sequences:

>Translated_576_residues
MTRLVNNPDNFPSQAVAGLVSAFPNHLRPVFGGVVRAARTDRKVALVVGGGSGHYPAFAGWVGPGFADGAVCGNIFSSPS
ASQAYAVCKAADRGAGLLIGFGNYAGDVLHFGQAAERLRSEGIDARCLLVTDDIASAPDHLKRRGIAGDLPVFKVTAAAC
EEGRDIDEVVAIFDRVNDRTRSLGVAFAGCTLPGADEPLFRVEAGQMGVGMGIHGEPGIHDETLGTADEVAAMLVNRLLA
DRPENPGTRVVPIVNGLGSTKYEELFVLWNDISRHLEKAGLAIVDPQVGEFVTSLDMAGVSLTLVWLDDVIEPLWLAACD
TPAYRRGTVGQVDFDTTPLPQEVERVMVANPGSRASRSLAGVIVEALEVVATRLSERSSELGRLDSVAGDGDHGIGMARG
SRAALAEARRVSGDGAGAATTLNAAGSAWSEHAGGTSGALWGAVLTAIGAVLGDEDPAGEDTIPRAARAALDAVIRLGGA
SVGDKTMVDAMDPFVTTLESSSDPLPQAWESACHAADMAAQATSEVTATVGRARPLGDKSLGTPDPGAVSFHEVVVAVGS
VLSKSALSNGRFRAQR
>Mature_575_residues
TRLVNNPDNFPSQAVAGLVSAFPNHLRPVFGGVVRAARTDRKVALVVGGGSGHYPAFAGWVGPGFADGAVCGNIFSSPSA
SQAYAVCKAADRGAGLLIGFGNYAGDVLHFGQAAERLRSEGIDARCLLVTDDIASAPDHLKRRGIAGDLPVFKVTAAACE
EGRDIDEVVAIFDRVNDRTRSLGVAFAGCTLPGADEPLFRVEAGQMGVGMGIHGEPGIHDETLGTADEVAAMLVNRLLAD
RPENPGTRVVPIVNGLGSTKYEELFVLWNDISRHLEKAGLAIVDPQVGEFVTSLDMAGVSLTLVWLDDVIEPLWLAACDT
PAYRRGTVGQVDFDTTPLPQEVERVMVANPGSRASRSLAGVIVEALEVVATRLSERSSELGRLDSVAGDGDHGIGMARGS
RAALAEARRVSGDGAGAATTLNAAGSAWSEHAGGTSGALWGAVLTAIGAVLGDEDPAGEDTIPRAARAALDAVIRLGGAS
VGDKTMVDAMDPFVTTLESSSDPLPQAWESACHAADMAAQATSEVTATVGRARPLGDKSLGTPDPGAVSFHEVVVAVGSV
LSKSALSNGRFRAQR

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=577, Percent_Identity=33.7954939341421, Blast_Score=238, Evalue=2e-62,
Organism=Escherichia coli, GI87081857, Length=358, Percent_Identity=34.3575418994413, Blast_Score=204, Evalue=2e-53,
Organism=Escherichia coli, GI1787449, Length=191, Percent_Identity=33.5078534031414, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565018, Length=574, Percent_Identity=32.404181184669, Blast_Score=231, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6323570, Length=568, Percent_Identity=29.9295774647887, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6321055, Length=547, Percent_Identity=29.981718464351, Blast_Score=180, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 59539; Mature: 59408

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLVNNPDNFPSQAVAGLVSAFPNHLRPVFGGVVRAARTDRKVALVVGGGSGHYPAFAG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEC
WVGPGFADGAVCGNIFSSPSASQAYAVCKAADRGAGLLIGFGNYAGDVLHFGQAAERLRS
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
EGIDARCLLVTDDIASAPDHLKRRGIAGDLPVFKVTAAACEEGRDIDEVVAIFDRVNDRT
CCCCEEEEEEECCHHCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHH
RSLGVAFAGCTLPGADEPLFRVEAGQMGVGMGIHGEPGIHDETLGTADEVAAMLVNRLLA
HHCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DRPENPGTRVVPIVNGLGSTKYEELFVLWNDISRHLEKAGLAIVDPQVGEFVTSLDMAGV
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCC
SLTLVWLDDVIEPLWLAACDTPAYRRGTVGQVDFDTTPLPQEVERVMVANPGSRASRSLA
EEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHHCCCCCHHHHHHH
GVIVEALEVVATRLSERSSELGRLDSVAGDGDHGIGMARGSRAALAEARRVSGDGAGAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEE
TLNAAGSAWSEHAGGTSGALWGAVLTAIGAVLGDEDPAGEDTIPRAARAALDAVIRLGGA
EECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
SVGDKTMVDAMDPFVTTLESSSDPLPQAWESACHAADMAAQATSEVTATVGRARPLGDKS
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LGTPDPGAVSFHEVVVAVGSVLSKSALSNGRFRAQR
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure 
TRLVNNPDNFPSQAVAGLVSAFPNHLRPVFGGVVRAARTDRKVALVVGGGSGHYPAFAG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEC
WVGPGFADGAVCGNIFSSPSASQAYAVCKAADRGAGLLIGFGNYAGDVLHFGQAAERLRS
CCCCCCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
EGIDARCLLVTDDIASAPDHLKRRGIAGDLPVFKVTAAACEEGRDIDEVVAIFDRVNDRT
CCCCEEEEEEECCHHCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCHHH
RSLGVAFAGCTLPGADEPLFRVEAGQMGVGMGIHGEPGIHDETLGTADEVAAMLVNRLLA
HHCCEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
DRPENPGTRVVPIVNGLGSTKYEELFVLWNDISRHLEKAGLAIVDPQVGEFVTSLDMAGV
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHCCC
SLTLVWLDDVIEPLWLAACDTPAYRRGTVGQVDFDTTPLPQEVERVMVANPGSRASRSLA
EEEEEEHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCHHHHHHHHHCCCCCHHHHHHH
GVIVEALEVVATRLSERSSELGRLDSVAGDGDHGIGMARGSRAALAEARRVSGDGAGAAT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEE
TLNAAGSAWSEHAGGTSGALWGAVLTAIGAVLGDEDPAGEDTIPRAARAALDAVIRLGGA
EECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
SVGDKTMVDAMDPFVTTLESSSDPLPQAWESACHAADMAAQATSEVTATVGRARPLGDKS
CCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LGTPDPGAVSFHEVVVAVGSVLSKSALSNGRFRAQR
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]