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The map label for this gene is putA [H]

Identifier: 50842107

GI number: 50842107

Start: 682635

End: 686093

Strand: Direct

Name: putA [H]

Synonym: PPA0620

Alternate gene names: 50842107

Gene position: 682635-686093 (Clockwise)

Preceding gene: 50842101

Following gene: 50842109

Centisome position: 26.66

GC content: 61.03

Gene sequence:

>3459_bases
ATGAGCATCGACGCTGATACTTGGGGCTCCCCATCCCCACGCCCTGCTGACCTGGCTGACGAGGCGGTTGACCAAGTCCA
CACCTGGTTACGAGATGCCAACGGTGCATCGAAGCGACGGACAGATCGTGCACAGATCGCTGCGGGATTGCTCTCCGACG
TGCTGTCCCACCCGGCTGGTCTGCCTTTCACTCTGGCCTTTATAGATCGGGTTGTCCGCCCTGAGGACGCTCGCACCGCA
GCGGCGAATCTTGCGGAACTGGCAAAGGTGGATTGTTCTTTTCTGCCTGCTGCACTGCAGGTGGCGGTGCGGGCAGGCGG
ACGAATGGCCCCCGTAGCTCCTAACGTCGTCGTCCCAGCTGCACGCCATGCCTTGCGGCAGCTGGTGGGCCATCTCGTCG
TTGATGCGCGACCGGCACAGTTGACTCGCACCCTCAAAGCACTGCGGAGTGCGGGTGTCAGGCTTAACCTCAACCTCCTG
GGCGAAGCTGTGTTGGGCGATCGCGAGGCGGCATCCCGCCTCGAAGGGACGATGGCTCTACTGGCCCGCGAGGATGTTGA
CTACGTCTCGATCAAGATTTCGGCTGTCGTCAACCAGCTCGACTTATGGGCTCACAAGGCGACGGTCGACGAGGTCGTTG
AGCAGCTGCTGCCGCTGTACCACTTGGCTGAGAACTCCCCGAAGCCGAAGTTCATCAACCTCGACATGGAGGAATATCAC
GACCTTGATCTGACAATGGAAGTCTTCCAGAAGCTCCTTGACCGCCCCGAATTGCGTCATGTGGAGGCTGGCATTGTCCT
TCAGGCCTACCTGCCCGACTCGCTGTCCGCTCTGCAAGGTCTTGTTGAGTGGGCTGACCGTCGTACCGCTGCCGGTGGGG
CGGGGATCAAAGTGCGGTTGGTCAAGGGCGCCAATCTCGCGATGGAGAAGGTAGATGCCGAGATTCACGGGTGGCAGCAG
ACCCCGTGGCCTTCCAAACTTGCCACTGACACCAACTACAAACGAATTCTGGACTGGGCGCTGACTCCCGAACGTACCCA
TTCGGTGCGGTATGGCGTCGCTGGCCACAATCTCTTTGACATTGCACTGACGAAGCTGCTTTGTGAGCATCGTGGGGTTC
GCGACCGGGTCGAATTCGAGATGCTGCTCGGCATGGCTCCTGACCAGGTTGAACGCATCGGAGCTGATGTTGGTGGGCTG
CTGCTCTACACGCCGGTTGTCGATCCTGCCCACTTTGATGTGGCGATCAGCTATCTGGTACGTCGGCTAGAAGAGAATGC
TGCTAGTGAAAACTTCATGTCGGCTATTTTTCAGCTCGGCCACGATTCCCAACTTTTCGCTCGCGAAGAGGCGAGGTTCC
GCACTGCAGTGGCTGGGATTACTCGAGAAGTGCCGAAGCCTCGTCGTGAGCAAGAGCCTGATCGGGCGCCGGATCTTTCC
AATGGGTTTGTCCAGTCCACTGACTCTGATCCCTCTCTGCCCAATATCCGCGTCTGGGCCGGTGAGGTTGCCGAGAAGAT
GAAGGGCTGTGAGCTGGGGGAGTCCACCCTGGCAAACAACCACCTCGACACCATTGCCGAGGTTAATGCCGTCATTGCCA
CCGCCCTTGAGGCTCAACACTCCTGGGCTGGGCGTGGCGGGAACGCACGTGCCGAAATACTGCGCACGGTGACGCACGCT
TTCGCTACTCGCCGGGGCGACCTTTTGGCAGTGGCCGGTGCTGAGACCGGCAAGATCCTGGCCGAAGGTGACGTCGAGGT
TTCTGAGGCTATCGACTTTGCTGCTTGGTATGTCGACCGAGCCGAGGAGCTCGAGGGCGTCGACGGTGCCCAGTTTGTGC
CGCCACGAGTGACCGTCGTCACCCCGCCGTGGAACTTCGCCCTGTCTATTACCGCCGGATCCACCCTTGCCGCTCTGGCC
GCCGGATCGTCAGTACTACTCAAGCCCGCTCCACAGGCCCGCCACTGTGCTGCCGTCATCTCTGAATGCCTGTGGGAGGC
TGGGATCCCGCGGGACGTTCTGCAGCTCGTCGATGTTGAGGAAAATGAGGCTGGTAAACACCTGGTGAGCCACCCCGAGG
TCGATCGGGTCATCCTCACGGGAGCTTGGGAAACGGCCAAGCTGTTCCGGTCGTGGCGTCATGACCTGCCAGTGCTGGCC
GAGACTAGTGGCAAGAACTCCATTATCGTCACAGAGAACGCTGACTACGACTTGGCCGCAGCCGACATCATCAAGTCGGC
TTTCGGCAATGCCGGACAGAAGTGCTCGGCAGCATCGCTCATTATCCTGGTGGGTCAGGCCTATCGGTCTCAGCGATTGC
GCCACCAGATCCTTGACGCCGCCTCCTCAATTCGGGTGGGATCGCCGTCGGACCTGCGCTCCCAGATGGGTCCGCTTGCC
GAGCCCGCCAGCGGCAAATTGCTCGATGGTTTGACGAAGCTTGACCCGGGCCAGGAATGGGCCCTGGAACCGGTGCGCAT
CGACGAGGAAGGCCGGTACTGGTCTCCCGGCGTGCGCAGTGGCATCAAACCGGGGGATCCGTACCACCTCACTGAGTACT
TCGGCCCGATTACCGGAATTATGTACGCTCCTGACTTAGCCACCGCTATCGCGTATCAGAACGGCACCGCTTTCGGTTTG
ACGGCCGGCCTGCACTCTCTGGACCCCGCCGAGATCGAGTTCTGGGCCGAGAGGGCCAATGCTGGAAACCTCTACGTCAA
CCGGAGCATCACGGGAGCCATCGTCGGTCGCCAACCCTTCGGTGGTTGGAAGCGTTCAGCGGTCGGTCCAGGTGCCAAGG
CCGGTGGCTACCACTATTTACAGGTGTTGGGGACTTGGCGTCGAGCTGAGGTGTCGGCCCCGACTCCGGCAGACCGTCCC
TGTGCTCTGGTCGAGCAGTTCGTCGGCCACATCGAGGGGTTGGTTACTCGTGACGAGCGTGCCTGGCTTCTTGACGCGGT
CGCCCGCGATGCTCGCGAGTGGGATGAGTGGTTTGGACGTTCTATCGACGTTGGCGGGCTGGAAAGAGAGCGCAACATCT
TGAGGTATCGCCCGGCCTCGACACAGGTAAGAGGCTGTGCTGACGCCAAACTGGTTGATGTCGCTCGCGTTGTTGCTGCG
GGACTCCTGGCTGCCGGCGACAATATCTCGGTGTGCCTGGACCCGAGTCTTGGCGAAGGGTTGGGCCGGGCGTTGCGTTC
GGTCGGTGTGGCCGTCACCACTGCTAGCGACGAGGACTGGTACGCCAGCCTAGGGGCTAGCCGAGTACGGCTCGTCGGTG
GTAATCCCTCCCGCGCTGCCGATGAGGCTGACGGTGATCCCGATTTAGCCTTGTGGGCCAACGAGGTCACCAGTGCCCCA
CAGGTTGAACTTCTACCTTTCCTGCGAGAGCAGTCGGTCTCGATGACAGCGCACCGATTCGGCAACCCGGATGCTGGGGT
CCTCTCGGTGAGATTGTGA

Upstream 100 bases:

>100_bases
GTCTGCGTCATGAGCTGTCCTCTCGAGGTATTCGCAGCGATATTCTTACATCGTTGGGCTGTGTACGTGCGTTGTTGTCT
GCTCGGGCTGCAGTCATGTC

Downstream 100 bases:

>100_bases
GGCGGCAGTCGCTGCGTGACGGGGTGCGACTTAACGGCGGGGATCGATAGCGATCTTGACACCGACGTGACCGCGCACGG
CGTCAACAGCTTCGGTCCAC

Product: NAD-dependent aldehyde dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1152; Mature: 1151

Protein sequence:

>1152_residues
MSIDADTWGSPSPRPADLADEAVDQVHTWLRDANGASKRRTDRAQIAAGLLSDVLSHPAGLPFTLAFIDRVVRPEDARTA
AANLAELAKVDCSFLPAALQVAVRAGGRMAPVAPNVVVPAARHALRQLVGHLVVDARPAQLTRTLKALRSAGVRLNLNLL
GEAVLGDREAASRLEGTMALLAREDVDYVSIKISAVVNQLDLWAHKATVDEVVEQLLPLYHLAENSPKPKFINLDMEEYH
DLDLTMEVFQKLLDRPELRHVEAGIVLQAYLPDSLSALQGLVEWADRRTAAGGAGIKVRLVKGANLAMEKVDAEIHGWQQ
TPWPSKLATDTNYKRILDWALTPERTHSVRYGVAGHNLFDIALTKLLCEHRGVRDRVEFEMLLGMAPDQVERIGADVGGL
LLYTPVVDPAHFDVAISYLVRRLEENAASENFMSAIFQLGHDSQLFAREEARFRTAVAGITREVPKPRREQEPDRAPDLS
NGFVQSTDSDPSLPNIRVWAGEVAEKMKGCELGESTLANNHLDTIAEVNAVIATALEAQHSWAGRGGNARAEILRTVTHA
FATRRGDLLAVAGAETGKILAEGDVEVSEAIDFAAWYVDRAEELEGVDGAQFVPPRVTVVTPPWNFALSITAGSTLAALA
AGSSVLLKPAPQARHCAAVISECLWEAGIPRDVLQLVDVEENEAGKHLVSHPEVDRVILTGAWETAKLFRSWRHDLPVLA
ETSGKNSIIVTENADYDLAAADIIKSAFGNAGQKCSAASLIILVGQAYRSQRLRHQILDAASSIRVGSPSDLRSQMGPLA
EPASGKLLDGLTKLDPGQEWALEPVRIDEEGRYWSPGVRSGIKPGDPYHLTEYFGPITGIMYAPDLATAIAYQNGTAFGL
TAGLHSLDPAEIEFWAERANAGNLYVNRSITGAIVGRQPFGGWKRSAVGPGAKAGGYHYLQVLGTWRRAEVSAPTPADRP
CALVEQFVGHIEGLVTRDERAWLLDAVARDAREWDEWFGRSIDVGGLERERNILRYRPASTQVRGCADAKLVDVARVVAA
GLLAAGDNISVCLDPSLGEGLGRALRSVGVAVTTASDEDWYASLGASRVRLVGGNPSRAADEADGDPDLALWANEVTSAP
QVELLPFLREQSVSMTAHRFGNPDAGVLSVRL

Sequences:

>Translated_1152_residues
MSIDADTWGSPSPRPADLADEAVDQVHTWLRDANGASKRRTDRAQIAAGLLSDVLSHPAGLPFTLAFIDRVVRPEDARTA
AANLAELAKVDCSFLPAALQVAVRAGGRMAPVAPNVVVPAARHALRQLVGHLVVDARPAQLTRTLKALRSAGVRLNLNLL
GEAVLGDREAASRLEGTMALLAREDVDYVSIKISAVVNQLDLWAHKATVDEVVEQLLPLYHLAENSPKPKFINLDMEEYH
DLDLTMEVFQKLLDRPELRHVEAGIVLQAYLPDSLSALQGLVEWADRRTAAGGAGIKVRLVKGANLAMEKVDAEIHGWQQ
TPWPSKLATDTNYKRILDWALTPERTHSVRYGVAGHNLFDIALTKLLCEHRGVRDRVEFEMLLGMAPDQVERIGADVGGL
LLYTPVVDPAHFDVAISYLVRRLEENAASENFMSAIFQLGHDSQLFAREEARFRTAVAGITREVPKPRREQEPDRAPDLS
NGFVQSTDSDPSLPNIRVWAGEVAEKMKGCELGESTLANNHLDTIAEVNAVIATALEAQHSWAGRGGNARAEILRTVTHA
FATRRGDLLAVAGAETGKILAEGDVEVSEAIDFAAWYVDRAEELEGVDGAQFVPPRVTVVTPPWNFALSITAGSTLAALA
AGSSVLLKPAPQARHCAAVISECLWEAGIPRDVLQLVDVEENEAGKHLVSHPEVDRVILTGAWETAKLFRSWRHDLPVLA
ETSGKNSIIVTENADYDLAAADIIKSAFGNAGQKCSAASLIILVGQAYRSQRLRHQILDAASSIRVGSPSDLRSQMGPLA
EPASGKLLDGLTKLDPGQEWALEPVRIDEEGRYWSPGVRSGIKPGDPYHLTEYFGPITGIMYAPDLATAIAYQNGTAFGL
TAGLHSLDPAEIEFWAERANAGNLYVNRSITGAIVGRQPFGGWKRSAVGPGAKAGGYHYLQVLGTWRRAEVSAPTPADRP
CALVEQFVGHIEGLVTRDERAWLLDAVARDAREWDEWFGRSIDVGGLERERNILRYRPASTQVRGCADAKLVDVARVVAA
GLLAAGDNISVCLDPSLGEGLGRALRSVGVAVTTASDEDWYASLGASRVRLVGGNPSRAADEADGDPDLALWANEVTSAP
QVELLPFLREQSVSMTAHRFGNPDAGVLSVRL
>Mature_1151_residues
SIDADTWGSPSPRPADLADEAVDQVHTWLRDANGASKRRTDRAQIAAGLLSDVLSHPAGLPFTLAFIDRVVRPEDARTAA
ANLAELAKVDCSFLPAALQVAVRAGGRMAPVAPNVVVPAARHALRQLVGHLVVDARPAQLTRTLKALRSAGVRLNLNLLG
EAVLGDREAASRLEGTMALLAREDVDYVSIKISAVVNQLDLWAHKATVDEVVEQLLPLYHLAENSPKPKFINLDMEEYHD
LDLTMEVFQKLLDRPELRHVEAGIVLQAYLPDSLSALQGLVEWADRRTAAGGAGIKVRLVKGANLAMEKVDAEIHGWQQT
PWPSKLATDTNYKRILDWALTPERTHSVRYGVAGHNLFDIALTKLLCEHRGVRDRVEFEMLLGMAPDQVERIGADVGGLL
LYTPVVDPAHFDVAISYLVRRLEENAASENFMSAIFQLGHDSQLFAREEARFRTAVAGITREVPKPRREQEPDRAPDLSN
GFVQSTDSDPSLPNIRVWAGEVAEKMKGCELGESTLANNHLDTIAEVNAVIATALEAQHSWAGRGGNARAEILRTVTHAF
ATRRGDLLAVAGAETGKILAEGDVEVSEAIDFAAWYVDRAEELEGVDGAQFVPPRVTVVTPPWNFALSITAGSTLAALAA
GSSVLLKPAPQARHCAAVISECLWEAGIPRDVLQLVDVEENEAGKHLVSHPEVDRVILTGAWETAKLFRSWRHDLPVLAE
TSGKNSIIVTENADYDLAAADIIKSAFGNAGQKCSAASLIILVGQAYRSQRLRHQILDAASSIRVGSPSDLRSQMGPLAE
PASGKLLDGLTKLDPGQEWALEPVRIDEEGRYWSPGVRSGIKPGDPYHLTEYFGPITGIMYAPDLATAIAYQNGTAFGLT
AGLHSLDPAEIEFWAERANAGNLYVNRSITGAIVGRQPFGGWKRSAVGPGAKAGGYHYLQVLGTWRRAEVSAPTPADRPC
ALVEQFVGHIEGLVTRDERAWLLDAVARDAREWDEWFGRSIDVGGLERERNILRYRPASTQVRGCADAKLVDVARVVAAG
LLAAGDNISVCLDPSLGEGLGRALRSVGVAVTTASDEDWYASLGASRVRLVGGNPSRAADEADGDPDLALWANEVTSAPQ
VELLPFLREQSVSMTAHRFGNPDAGVLSVRL

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=483, Percent_Identity=27.9503105590062, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI25777734, Length=483, Percent_Identity=27.9503105590062, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI238859541, Length=484, Percent_Identity=28.099173553719, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI153266822, Length=407, Percent_Identity=27.2727272727273, Blast_Score=127, Evalue=6e-29,
Organism=Homo sapiens, GI12007648, Length=442, Percent_Identity=26.0180995475113, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI25777730, Length=422, Percent_Identity=25.3554502369668, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI115387104, Length=423, Percent_Identity=24.113475177305, Blast_Score=118, Evalue=4e-26,
Organism=Homo sapiens, GI25777732, Length=529, Percent_Identity=25.7088846880907, Blast_Score=114, Evalue=5e-25,
Organism=Homo sapiens, GI25777728, Length=359, Percent_Identity=27.8551532033426, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI25777724, Length=359, Percent_Identity=27.8551532033426, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI21614513, Length=344, Percent_Identity=26.7441860465116, Blast_Score=110, Evalue=7e-24,
Organism=Homo sapiens, GI21361176, Length=333, Percent_Identity=30.03003003003, Blast_Score=107, Evalue=7e-23,
Organism=Homo sapiens, GI4507229, Length=422, Percent_Identity=26.7772511848341, Blast_Score=107, Evalue=8e-23,
Organism=Homo sapiens, GI11095441, Length=407, Percent_Identity=23.5872235872236, Blast_Score=107, Evalue=1e-22,
Organism=Homo sapiens, GI238814322, Length=323, Percent_Identity=25.3869969040248, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI25777721, Length=427, Percent_Identity=26.2295081967213, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI188035924, Length=490, Percent_Identity=23.6734693877551, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI310128103, Length=471, Percent_Identity=23.7791932059448, Blast_Score=94, Evalue=9e-19,
Organism=Homo sapiens, GI310128093, Length=452, Percent_Identity=23.6725663716814, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI25952152, Length=432, Percent_Identity=24.0740740740741, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI71773324, Length=392, Percent_Identity=24.234693877551, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI73695881, Length=329, Percent_Identity=25.2279635258359, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI73695879, Length=329, Percent_Identity=25.2279635258359, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI206597441, Length=350, Percent_Identity=24.2857142857143, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI206597439, Length=350, Percent_Identity=24.2857142857143, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI22907049, Length=350, Percent_Identity=24.2857142857143, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI301500698, Length=273, Percent_Identity=27.4725274725275, Blast_Score=84, Evalue=7e-16,
Organism=Homo sapiens, GI4502043, Length=329, Percent_Identity=24.3161094224924, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI238814371, Length=329, Percent_Identity=24.3161094224924, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI310128091, Length=376, Percent_Identity=24.2021276595745, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI310128087, Length=282, Percent_Identity=23.758865248227, Blast_Score=67, Evalue=9e-11,
Organism=Escherichia coli, GI1787250, Length=812, Percent_Identity=29.8029556650246, Blast_Score=216, Evalue=5e-57,
Organism=Escherichia coli, GI1789015, Length=431, Percent_Identity=29.2343387470998, Blast_Score=142, Evalue=2e-34,
Organism=Escherichia coli, GI87081926, Length=415, Percent_Identity=25.5421686746988, Blast_Score=125, Evalue=2e-29,
Organism=Escherichia coli, GI1787684, Length=426, Percent_Identity=25.1173708920188, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI87081896, Length=315, Percent_Identity=30.4761904761905, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1788042, Length=435, Percent_Identity=27.816091954023, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1787558, Length=320, Percent_Identity=27.1875, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1786504, Length=428, Percent_Identity=25.9345794392523, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI1787715, Length=367, Percent_Identity=25.3405994550409, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI87082295, Length=430, Percent_Identity=26.2790697674419, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25143874, Length=434, Percent_Identity=28.110599078341, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI25143876, Length=434, Percent_Identity=28.110599078341, Blast_Score=146, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI115534176, Length=468, Percent_Identity=26.4957264957265, Blast_Score=129, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI133930964, Length=323, Percent_Identity=28.4829721362229, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI32564736, Length=315, Percent_Identity=27.6190476190476, Blast_Score=110, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25144435, Length=315, Percent_Identity=27.6190476190476, Blast_Score=110, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17534447, Length=462, Percent_Identity=27.9220779220779, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17534119, Length=483, Percent_Identity=23.8095238095238, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17562198, Length=314, Percent_Identity=26.1146496815287, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71995606, Length=318, Percent_Identity=27.0440251572327, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115532534, Length=342, Percent_Identity=28.6549707602339, Blast_Score=94, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71986308, Length=454, Percent_Identity=23.3480176211454, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17551164, Length=436, Percent_Identity=24.5412844036697, Blast_Score=92, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71995613, Length=275, Percent_Identity=26.5454545454545, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32564151, Length=428, Percent_Identity=25.7009345794392, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71990744, Length=292, Percent_Identity=28.0821917808219, Blast_Score=69, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321826, Length=427, Percent_Identity=27.8688524590164, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6320917, Length=319, Percent_Identity=29.153605015674, Blast_Score=115, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319478, Length=438, Percent_Identity=24.4292237442922, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6324950, Length=329, Percent_Identity=27.9635258358663, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6323821, Length=345, Percent_Identity=24.3478260869565, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323822, Length=331, Percent_Identity=25.0755287009063, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321828, Length=453, Percent_Identity=23.1788079470199, Blast_Score=95, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6325196, Length=453, Percent_Identity=23.841059602649, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281362580, Length=441, Percent_Identity=25.3968253968254, Blast_Score=126, Evalue=1e-28,
Organism=Drosophila melanogaster, GI62472918, Length=441, Percent_Identity=25.3968253968254, Blast_Score=126, Evalue=1e-28,
Organism=Drosophila melanogaster, GI62472926, Length=441, Percent_Identity=25.3968253968254, Blast_Score=126, Evalue=1e-28,
Organism=Drosophila melanogaster, GI62472936, Length=441, Percent_Identity=25.3968253968254, Blast_Score=126, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21356737, Length=441, Percent_Identity=25.3968253968254, Blast_Score=126, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24650465, Length=430, Percent_Identity=25.3488372093023, Blast_Score=113, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24668425, Length=453, Percent_Identity=26.0485651214128, Blast_Score=113, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24668417, Length=453, Percent_Identity=26.0485651214128, Blast_Score=113, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24668413, Length=453, Percent_Identity=26.0485651214128, Blast_Score=113, Evalue=7e-25,
Organism=Drosophila melanogaster, GI20129399, Length=356, Percent_Identity=28.0898876404494, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24585660, Length=324, Percent_Identity=25.9259259259259, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571798, Length=447, Percent_Identity=25.503355704698, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28571796, Length=447, Percent_Identity=25.503355704698, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28571794, Length=447, Percent_Identity=25.503355704698, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28571802, Length=447, Percent_Identity=25.503355704698, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28571800, Length=447, Percent_Identity=25.503355704698, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI28571806, Length=447, Percent_Identity=25.503355704698, Blast_Score=97, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24666674, Length=472, Percent_Identity=24.7881355932203, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24638876, Length=407, Percent_Identity=24.3243243243243, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24638878, Length=407, Percent_Identity=24.3243243243243, Blast_Score=87, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28574525, Length=460, Percent_Identity=23.2608695652174, Blast_Score=78, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 124556; Mature: 124425

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDADTWGSPSPRPADLADEAVDQVHTWLRDANGASKRRTDRAQIAAGLLSDVLSHPAG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LPFTLAFIDRVVRPEDARTAAANLAELAKVDCSFLPAALQVAVRAGGRMAPVAPNVVVPA
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
ARHALRQLVGHLVVDARPAQLTRTLKALRSAGVRLNLNLLGEAVLGDREAASRLEGTMAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHHHHHHHHH
LAREDVDYVSIKISAVVNQLDLWAHKATVDEVVEQLLPLYHLAENSPKPKFINLDMEEYH
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHC
DLDLTMEVFQKLLDRPELRHVEAGIVLQAYLPDSLSALQGLVEWADRRTAAGGAGIKVRL
CCCHHHHHHHHHHCCCCHHEECCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
VKGANLAMEKVDAEIHGWQQTPWPSKLATDTNYKRILDWALTPERTHSVRYGVAGHNLFD
EECCCHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCEEEECCCCCHHH
IALTKLLCEHRGVRDRVEFEMLLGMAPDQVERIGADVGGLLLYTPVVDPAHFDVAISYLV
HHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
RRLEENAASENFMSAIFQLGHDSQLFAREEARFRTAVAGITREVPKPRREQEPDRAPDLS
HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NGFVQSTDSDPSLPNIRVWAGEVAEKMKGCELGESTLANNHLDTIAEVNAVIATALEAQH
CCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
SWAGRGGNARAEILRTVTHAFATRRGDLLAVAGAETGKILAEGDVEVSEAIDFAAWYVDR
HCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHH
AEELEGVDGAQFVPPRVTVVTPPWNFALSITAGSTLAALAAGSSVLLKPAPQARHCAAVI
HHHCCCCCCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHCCCCEEECCCCCHHHHHHHH
SECLWEAGIPRDVLQLVDVEENEAGKHLVSHPEVDRVILTGAWETAKLFRSWRHDLPVLA
HHHHHHCCCCHHHHHHHCCCCCCCCCHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEE
ETSGKNSIIVTENADYDLAAADIIKSAFGNAGQKCSAASLIILVGQAYRSQRLRHQILDA
ECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECHHHHHHHHHHHHHHH
ASSIRVGSPSDLRSQMGPLAEPASGKLLDGLTKLDPGQEWALEPVRIDEEGRYWSPGVRS
HHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHCCCCEEECCCCCEECCHHHC
GIKPGDPYHLTEYFGPITGIMYAPDLATAIAYQNGTAFGLTAGLHSLDPAEIEFWAERAN
CCCCCCCCCHHHHHHHHHHHEECCHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHCC
AGNLYVNRSITGAIVGRQPFGGWKRSAVGPGAKAGGYHYLQVLGTWRRAEVSAPTPADRP
CCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
CALVEQFVGHIEGLVTRDERAWLLDAVARDAREWDEWFGRSIDVGGLERERNILRYRPAS
HHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHEECCCC
TQVRGCADAKLVDVARVVAAGLLAAGDNISVCLDPSLGEGLGRALRSVGVAVTTASDEDW
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCEEEEECCCCHH
YASLGASRVRLVGGNPSRAADEADGDPDLALWANEVTSAPQVELLPFLREQSVSMTAHRF
HHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEHHHHCCCCCHHHHHHHHHHCCHHHHHHC
GNPDAGVLSVRL
CCCCCCEEEEEC
>Mature Secondary Structure 
SIDADTWGSPSPRPADLADEAVDQVHTWLRDANGASKRRTDRAQIAAGLLSDVLSHPAG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
LPFTLAFIDRVVRPEDARTAAANLAELAKVDCSFLPAALQVAVRAGGRMAPVAPNVVVPA
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHH
ARHALRQLVGHLVVDARPAQLTRTLKALRSAGVRLNLNLLGEAVLGDREAASRLEGTMAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHHHHHHHHH
LAREDVDYVSIKISAVVNQLDLWAHKATVDEVVEQLLPLYHLAENSPKPKFINLDMEEYH
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHC
DLDLTMEVFQKLLDRPELRHVEAGIVLQAYLPDSLSALQGLVEWADRRTAAGGAGIKVRL
CCCHHHHHHHHHHCCCCHHEECCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
VKGANLAMEKVDAEIHGWQQTPWPSKLATDTNYKRILDWALTPERTHSVRYGVAGHNLFD
EECCCHHHHHHHHHHCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCEEEECCCCCHHH
IALTKLLCEHRGVRDRVEFEMLLGMAPDQVERIGADVGGLLLYTPVVDPAHFDVAISYLV
HHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHH
RRLEENAASENFMSAIFQLGHDSQLFAREEARFRTAVAGITREVPKPRREQEPDRAPDLS
HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NGFVQSTDSDPSLPNIRVWAGEVAEKMKGCELGESTLANNHLDTIAEVNAVIATALEAQH
CCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
SWAGRGGNARAEILRTVTHAFATRRGDLLAVAGAETGKILAEGDVEVSEAIDFAAWYVDR
HCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHH
AEELEGVDGAQFVPPRVTVVTPPWNFALSITAGSTLAALAAGSSVLLKPAPQARHCAAVI
HHHCCCCCCCCCCCCEEEEEECCCCEEEEEECCCHHHHHHCCCCEEECCCCCHHHHHHHH
SECLWEAGIPRDVLQLVDVEENEAGKHLVSHPEVDRVILTGAWETAKLFRSWRHDLPVLA
HHHHHHCCCCHHHHHHHCCCCCCCCCHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEE
ETSGKNSIIVTENADYDLAAADIIKSAFGNAGQKCSAASLIILVGQAYRSQRLRHQILDA
ECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHEEEEEECHHHHHHHHHHHHHHH
ASSIRVGSPSDLRSQMGPLAEPASGKLLDGLTKLDPGQEWALEPVRIDEEGRYWSPGVRS
HHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHCCCCEEECCCCCEECCHHHC
GIKPGDPYHLTEYFGPITGIMYAPDLATAIAYQNGTAFGLTAGLHSLDPAEIEFWAERAN
CCCCCCCCCHHHHHHHHHHHEECCHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHCC
AGNLYVNRSITGAIVGRQPFGGWKRSAVGPGAKAGGYHYLQVLGTWRRAEVSAPTPADRP
CCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
CALVEQFVGHIEGLVTRDERAWLLDAVARDAREWDEWFGRSIDVGGLERERNILRYRPAS
HHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHEECCCC
TQVRGCADAKLVDVARVVAAGLLAAGDNISVCLDPSLGEGLGRALRSVGVAVTTASDEDW
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCEEEEECCCCHH
YASLGASRVRLVGGNPSRAADEADGDPDLALWANEVTSAPQVELLPFLREQSVSMTAHRF
HHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEHHHHCCCCCHHHHHHHHHHCCHHHHHHC
GNPDAGVLSVRL
CCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]