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The map label for this gene is ugd [H]

Identifier: 50842079

GI number: 50842079

Start: 654404

End: 655570

Strand: Reverse

Name: ugd [H]

Synonym: PPA0593

Alternate gene names: 50842079

Gene position: 655570-654404 (Counterclockwise)

Preceding gene: 50842080

Following gene: 50842065

Centisome position: 25.61

GC content: 58.78

Gene sequence:

>1167_bases
GTGAAGATTGCCGTTGCAGGATTGGGCTACGTCGGAATGGCCAATGCCGTGTTGCTGGCCCAGCATAACAGCGTCGTCGC
TATCGATATCGACGCTGAGCGGGTCGATATGGTCAACAACCGGCATACCACCATCGTTGATCCCCTCATAGCGGAGTACT
TGGCCCATCACAACCTGGACCTGCGCGCCACCACCGACCCGCAGGAAGCGTACCGGGGAGCAGACTTCGTCGTCATCGCC
ACCCCGACCAACTATGACCCTGGCCAAAACTACTTCGACACCTCAAGCGTCGACGAGGTCCTTGATCTGGTCCAGGAACT
CGCCCCTCACACGACGACCGTCATTAAATCAACAATCCCGGTGGGCTTCGTCGAGGGCGTTCGCAAGGAGCGCTCCGGGC
TTGACGTCATCTTCTCCCCCGAGTTCCTGCGAGAAGGTAAGGCTCTGTTCGATAACCTTCACCCCTCGCGGATCGTCGTC
GGGGCGGACTCCCCCAAAGCCCACCTCTTCGCCGACCTCATGGCTGCCGGGGCCGTTGACACCAATGTCCCGGTGCTCTT
CGTCGGTGCCACCGAGGCCGAGGCCATCAAGCTCTTCGCCAACACCTACCTGGCGATGCGGGTGTCCTTCTTCAACGAGC
TCGACACCTATGCCTCCCAGCGCGGGCTGTCTACCCGTCAAGTCATTGACGGGGTCTGCCTCGATCCTCGCATTGGCAAC
CACTACAACAACCCGTCCTTCGGGTACGGCGGTTACTGCCTGCCTAAAGACACCCGTCAACTATTAGCCAATTACCAGGA
CGTGCCACAGACCCTCATCCAGGCCATCGTCGACTCCAACACCGTGCGCAAAGACTTTATCGCCTCTGACATCATTGCCA
GGGACCCGAAACGGGTGGGGATCTTCCGTCTGGTCATGAAGGCAGGTTCGGACAACTTCCGTTCCTCCTCGATCCAAGGC
GTCATGAAGCGCATCAAGGCGAAGGGCATCGAGGTGGTCGTCTACGAGCCGACCTTTGACGGCGACGAGTTTTTCCACTC
GGAGGTCACCAAGAACCTTGCCTTCTTCAAAGCTAACTGCGACGTCATCATTGCCAACCGGATGTCACCGGATTTATCCG
ATGTCGCTGACAAGGTCTACACCCGGGATCTCTTCGGTGGGGACTGA

Upstream 100 bases:

>100_bases
GAGCCCTGCAACGAGGTGTTGCCGGAGGCCGGAAAAGGTGACTGGTGTCGTACGCCACATCGCTGCCTTAAACTCATGGG
GACCCCCGAAAGGACCTCCC

Downstream 100 bases:

>100_bases
CCCGGGCGATGCCGGTCACAAGGATCAGGCTCCGCTAGACCAAACGACCTGACCGACTTCCCGGATGAGAACCGAGCAGC
CATCGCGCACATCAAGTTCG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIAVAGLGYVGMANAVLLAQHNSVVAIDIDAERVDMVNNRHTTIVDPLIAEYLAHHNLDLRATTDPQEAYRGADFVVIA
TPTNYDPGQNYFDTSSVDEVLDLVQELAPHTTTVIKSTIPVGFVEGVRKERSGLDVIFSPEFLREGKALFDNLHPSRIVV
GADSPKAHLFADLMAAGAVDTNVPVLFVGATEAEAIKLFANTYLAMRVSFFNELDTYASQRGLSTRQVIDGVCLDPRIGN
HYNNPSFGYGGYCLPKDTRQLLANYQDVPQTLIQAIVDSNTVRKDFIASDIIARDPKRVGIFRLVMKAGSDNFRSSSIQG
VMKRIKAKGIEVVVYEPTFDGDEFFHSEVTKNLAFFKANCDVIIANRMSPDLSDVADKVYTRDLFGGD

Sequences:

>Translated_388_residues
MKIAVAGLGYVGMANAVLLAQHNSVVAIDIDAERVDMVNNRHTTIVDPLIAEYLAHHNLDLRATTDPQEAYRGADFVVIA
TPTNYDPGQNYFDTSSVDEVLDLVQELAPHTTTVIKSTIPVGFVEGVRKERSGLDVIFSPEFLREGKALFDNLHPSRIVV
GADSPKAHLFADLMAAGAVDTNVPVLFVGATEAEAIKLFANTYLAMRVSFFNELDTYASQRGLSTRQVIDGVCLDPRIGN
HYNNPSFGYGGYCLPKDTRQLLANYQDVPQTLIQAIVDSNTVRKDFIASDIIARDPKRVGIFRLVMKAGSDNFRSSSIQG
VMKRIKAKGIEVVVYEPTFDGDEFFHSEVTKNLAFFKANCDVIIANRMSPDLSDVADKVYTRDLFGGD
>Mature_388_residues
MKIAVAGLGYVGMANAVLLAQHNSVVAIDIDAERVDMVNNRHTTIVDPLIAEYLAHHNLDLRATTDPQEAYRGADFVVIA
TPTNYDPGQNYFDTSSVDEVLDLVQELAPHTTTVIKSTIPVGFVEGVRKERSGLDVIFSPEFLREGKALFDNLHPSRIVV
GADSPKAHLFADLMAAGAVDTNVPVLFVGATEAEAIKLFANTYLAMRVSFFNELDTYASQRGLSTRQVIDGVCLDPRIGN
HYNNPSFGYGGYCLPKDTRQLLANYQDVPQTLIQAIVDSNTVRKDFIASDIIARDPKRVGIFRLVMKAGSDNFRSSSIQG
VMKRIKAKGIEVVVYEPTFDGDEFFHSEVTKNLAFFKANCDVIIANRMSPDLSDVADKVYTRDLFGGD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=365, Percent_Identity=27.6712328767123, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI296040438, Length=255, Percent_Identity=28.6274509803922, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI296040443, Length=355, Percent_Identity=24.2253521126761, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=62.8865979381443, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI48994968, Length=379, Percent_Identity=24.0105540897098, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17560350, Length=375, Percent_Identity=26.9333333333333, Blast_Score=118, Evalue=7e-27,
Organism=Drosophila melanogaster, GI17136908, Length=385, Percent_Identity=26.2337662337662, Blast_Score=120, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 42661; Mature: 42661

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVAGLGYVGMANAVLLAQHNSVVAIDIDAERVDMVNNRHTTIVDPLIAEYLAHHNLD
CEEEEECCCHHHHHCEEEEEECCCEEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
LRATTDPQEAYRGADFVVIATPTNYDPGQNYFDTSSVDEVLDLVQELAPHTTTVIKSTIP
EEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCC
VGFVEGVRKERSGLDVIFSPEFLREGKALFDNLHPSRIVVGADSPKAHLFADLMAAGAVD
HHHHHHHHHHHCCCEEEECHHHHHCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCC
TNVPVLFVGATEAEAIKLFANTYLAMRVSFFNELDTYASQRGLSTRQVIDGVCLDPRIGN
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEECCCCCCC
HYNNPSFGYGGYCLPKDTRQLLANYQDVPQTLIQAIVDSNTVRKDFIASDIIARDPKRVG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHH
IFRLVMKAGSDNFRSSSIQGVMKRIKAKGIEVVVYEPTFDGDEFFHSEVTKNLAFFKANC
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHEEEECCC
DVIIANRMSPDLSDVADKVYTRDLFGGD
CEEEECCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIAVAGLGYVGMANAVLLAQHNSVVAIDIDAERVDMVNNRHTTIVDPLIAEYLAHHNLD
CEEEEECCCHHHHHCEEEEEECCCEEEEEECHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
LRATTDPQEAYRGADFVVIATPTNYDPGQNYFDTSSVDEVLDLVQELAPHTTTVIKSTIP
EEECCCHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHCC
VGFVEGVRKERSGLDVIFSPEFLREGKALFDNLHPSRIVVGADSPKAHLFADLMAAGAVD
HHHHHHHHHHHCCCEEEECHHHHHCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCC
TNVPVLFVGATEAEAIKLFANTYLAMRVSFFNELDTYASQRGLSTRQVIDGVCLDPRIGN
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEECCCCCCC
HYNNPSFGYGGYCLPKDTRQLLANYQDVPQTLIQAIVDSNTVRKDFIASDIIARDPKRVG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHH
IFRLVMKAGSDNFRSSSIQGVMKRIKAKGIEVVVYEPTFDGDEFFHSEVTKNLAFFKANC
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHEEEECCC
DVIIANRMSPDLSDVADKVYTRDLFGGD
CEEEECCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]