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The map label for this gene is 50842080

Identifier: 50842080

GI number: 50842080

Start: 655713

End: 656651

Strand: Reverse

Name: 50842080

Synonym: PPA0594

Alternate gene names: NA

Gene position: 656651-655713 (Counterclockwise)

Preceding gene: 50842085

Following gene: 50842079

Centisome position: 25.65

GC content: 62.83

Gene sequence:

>939_bases
ATGGCATTGCAGGAAATCGAATTCACTTCACGCAACAGACGCGACGCCATCCAGGCATGGGCTTACGAACCAGTGGGAAC
GCCGGCGGCCGTCGTCCAGATCATCCACGGTCTGGGTGAGCACTCACGCCGCTACCTGCACATGATTTCAGCTCTGCTAG
ATGCGAGCTTTATCGTCGTCGCTGACGACCATGCCGGCCACGGTCGCACCGCCATGCAGTCGGGCCAGTGGGCTGACGCG
GGCGACAACTCCGCCGAGGTTGTCATTTCCGACGAGCTCACACTGCAGCAGCAGTTGACAGGCCAGTTCAATGATCTGCC
CTGGGTGGTCTTCGGTCACAGTTGGGGTTCCCTGATTGCCCGTGCGATGGCTACCCGCCCCAACGCCCGCCTCGACGGCT
TAGCACTAGGCGGCGTCGTGGCGCAGCTACGCGGCCTCGAGACCACCCTTGACCACGAGGCGCTCGCGAAGGCCATGGCG
ACCAACCCGGCCGGTCCCGCCCCCGAGTCCCTCGTCGCCCAAATGTTTGACGGATGTACTGACCGCTTGAGCGAAGGCGA
CGGCCCCACCGGCTGGGTGGCTCGTAACAGGGACGTGGTTGCCGACTACGGCAAAGATAAGTTCAATAATTTCGGTGCCC
AAATGAGCACGCGCTTCCTGCAGGGTTTCGCCGACATCTACGACATGGCTAACGGGGAGGGCTTCTATGCGGCGATGCCG
AAGATCCCCATCGCCTTGTTTGCGGGCAGCGAGGATCCTGCGGGCAACTTCGGCACCGGCGTGCAGGCTGTCGCGCAACG
CCTGCGAAGGGACGGGCACGACGTCGAGCTACACCTATACGACGGCCTGCGCCACGAGGTGCACAACGAGCCCGAGTCGC
GTGCCGACGTGGAATCGAGCCTCGTCACCTTCGTAGATCGAGTGGCCAAGAGGAATTAG

Upstream 100 bases:

>100_bases
TTTGGACATGACACCCGTACTCACCAGCCATTCACCAGCGGCCCACGAGGTGTTAGCCTCGCCGCTATTGACAGCTGAGC
CGCTGACAAGGAGGTCAATC

Downstream 100 bases:

>100_bases
GCGGTCGCGATAGTGATCGTTGCAGGGCTCACCCTGGACGGCGAGCCCTGCAACGAGGTGTTGCCGGAGGCCGGAAAAGG
TGACTGGTGTCGTACGCCAC

Product: putative lysophospholipase

Products: glycerophosphocholine; carboxylate

Alternate protein names: Alpha/Beta Hydrolase Fold; Alpha/Beta Fold Family Hydrolase; Alpha/Beta Hydrolase Fold Protein; Hydrolase Alpha/Beta Fold Family; Hydrolase; Alpha/Beta Hydrolase; Hydrolase Alpha/Beta Hydrolase Fold Family; Lipase; Lysophospholipase Protein; Lysophospholipase-Like Protein; Acylglycerol Lipase; Carboxylic Ester Hydrolase; Monoacylglycerol Lipase; Alpha/Beta Hydrolase Family Protein; S33 Family Lysophospholipase; Aminopeptidase; Hydrolase Alpha/Beta Fold Family Protein; Hydrolase Alpha/Beta Domain-Containing Protein; Lysophospholipase/Monoglyceride Lipase

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MALQEIEFTSRNRRDAIQAWAYEPVGTPAAVVQIIHGLGEHSRRYLHMISALLDASFIVVADDHAGHGRTAMQSGQWADA
GDNSAEVVISDELTLQQQLTGQFNDLPWVVFGHSWGSLIARAMATRPNARLDGLALGGVVAQLRGLETTLDHEALAKAMA
TNPAGPAPESLVAQMFDGCTDRLSEGDGPTGWVARNRDVVADYGKDKFNNFGAQMSTRFLQGFADIYDMANGEGFYAAMP
KIPIALFAGSEDPAGNFGTGVQAVAQRLRRDGHDVELHLYDGLRHEVHNEPESRADVESSLVTFVDRVAKRN

Sequences:

>Translated_312_residues
MALQEIEFTSRNRRDAIQAWAYEPVGTPAAVVQIIHGLGEHSRRYLHMISALLDASFIVVADDHAGHGRTAMQSGQWADA
GDNSAEVVISDELTLQQQLTGQFNDLPWVVFGHSWGSLIARAMATRPNARLDGLALGGVVAQLRGLETTLDHEALAKAMA
TNPAGPAPESLVAQMFDGCTDRLSEGDGPTGWVARNRDVVADYGKDKFNNFGAQMSTRFLQGFADIYDMANGEGFYAAMP
KIPIALFAGSEDPAGNFGTGVQAVAQRLRRDGHDVELHLYDGLRHEVHNEPESRADVESSLVTFVDRVAKRN
>Mature_311_residues
ALQEIEFTSRNRRDAIQAWAYEPVGTPAAVVQIIHGLGEHSRRYLHMISALLDASFIVVADDHAGHGRTAMQSGQWADAG
DNSAEVVISDELTLQQQLTGQFNDLPWVVFGHSWGSLIARAMATRPNARLDGLALGGVVAQLRGLETTLDHEALAKAMAT
NPAGPAPESLVAQMFDGCTDRLSEGDGPTGWVARNRDVVADYGKDKFNNFGAQMSTRFLQGFADIYDMANGEGFYAAMPK
IPIALFAGSEDPAGNFGTGVQAVAQRLRRDGHDVELHLYDGLRHEVHNEPESRADVESSLVTFVDRVAKRN

Specific function: Unknown

COG id: COG2267

COG function: function code I; Lysophospholipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI51242953, Length=275, Percent_Identity=24.7272727272727, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI6005786, Length=275, Percent_Identity=24.7272727272727, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.5

Molecular weight: Translated: 33870; Mature: 33739

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQEIEFTSRNRRDAIQAWAYEPVGTPAAVVQIIHGLGEHSRRYLHMISALLDASFIVV
CCCCCCCHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ADDHAGHGRTAMQSGQWADAGDNSAEVVISDELTLQQQLTGQFNDLPWVVFGHSWGSLIA
ECCCCCCCCHHHCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEEECCCHHHHHH
RAMATRPNARLDGLALGGVVAQLRGLETTLDHEALAKAMATNPAGPAPESLVAQMFDGCT
HHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
DRLSEGDGPTGWVARNRDVVADYGKDKFNNFGAQMSTRFLQGFADIYDMANGEGFYAAMP
HHHHCCCCCCCCEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
KIPIALFAGSEDPAGNFGTGVQAVAQRLRRDGHDVELHLYDGLRHEVHNEPESRADVESS
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCHHHHHHHHH
LVTFVDRVAKRN
HHHHHHHHHCCC
>Mature Secondary Structure 
ALQEIEFTSRNRRDAIQAWAYEPVGTPAAVVQIIHGLGEHSRRYLHMISALLDASFIVV
CCCCCCHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
ADDHAGHGRTAMQSGQWADAGDNSAEVVISDELTLQQQLTGQFNDLPWVVFGHSWGSLIA
ECCCCCCCCHHHCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCEEEECCCHHHHHH
RAMATRPNARLDGLALGGVVAQLRGLETTLDHEALAKAMATNPAGPAPESLVAQMFDGCT
HHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
DRLSEGDGPTGWVARNRDVVADYGKDKFNNFGAQMSTRFLQGFADIYDMANGEGFYAAMP
HHHHCCCCCCCCEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
KIPIALFAGSEDPAGNFGTGVQAVAQRLRRDGHDVELHLYDGLRHEVHNEPESRADVESS
CCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCHHHHHHHHH
LVTFVDRVAKRN
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-lysophosphatidylcholine; H2O

Specific reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA