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The map label for this gene is engD [H]

Identifier: 50842061

GI number: 50842061

Start: 636616

End: 637689

Strand: Direct

Name: engD [H]

Synonym: PPA0575

Alternate gene names: 50842061

Gene position: 636616-637689 (Clockwise)

Preceding gene: 50842060

Following gene: 50842062

Centisome position: 24.87

GC content: 57.73

Gene sequence:

>1074_bases
GTGGCACTTACGATTGGAATCGTCGGTCTTCCCAACGCCGGCAAGTCGACTCTGTTCAACGCGCTGACCAAGAATGACGT
CTTGGCGGCGAACTACCCCTTCGCGACCATTGAGCCGAATGTTGGCGTGGTCGGGGTGCCGGACAAGCGCCTCGATGTGC
TGACGGAGATGTTTCATTCCGCTAAGACCATTCCTGCGACGGTGTCCTTCGTCGACATCGCCGGAATCGTCAAAGGCGCT
AGCAAAGGTGAGGGGATGGGCAACGAGTTCCTCTCTAACATTCGTGAAGCCGACGCCATCTGCCAGGTGACAAGGTGTTT
CGCAGACGACGATGTCACCCACGTCAACGGTCACGTCGATCCCTCCGACGACATCGAGACCATTACTACAGAGCTCGTGC
TCGCTGATCTGCAGACGATGGAGAAGCAACTGCCCAAGTTGCAAAAAGAAGCCGCGATCAAGAAGGAGTCTCGTCCCAAA
GTCGAGGCGTGGGAGCAGGCTAAGGCGGTGCTCGAAGAGGGCAAGACGATCTTCTCAGCCGGGCTCGATCCCGAGCCGTT
GCATGACCTCTTCCTGCTGACGACAAAGCCCTTCATCTACGTCTTTAACTGTGACCAGGATCAGCTCGCTGACGCCGATT
TCCAGGCCAAGATGGAGAAGTTGGTGGCTCCTGCTGAGGCGATCTTCTTGGATGCTGAGTTTGAGGCTGAACTGGCCGAG
ATGGAGCCCGAGGACGCTGCTGAGTTCCTTGCGGATGCGGGTATCGAGGAACCCGGTCTAGACAAGCTCGCGCGGGTGGG
CTTCGACACTCTTGGTCTACAGACCTTCCTAACTGCGGGGGAGAAGGAGTCCCGCGCATGGACGATTCACAAGGGCGACA
CCGCCCCTGAGGCTGCTGGCGTCATCCATACCGACTTCCAGAAGGGGTTCATCAAGGCCCAGGTGGTGTCCTTCGGCGAC
CTTGTTGAATTTGGCGGCGAAAAGGAGGCCCAGGCTGCTGGGAAGTTGCGGTTGGAGGGCAAGGAGTACGTTATGCAGGA
CGGTGACGTAGTGGAATTCCGATTTAACGTGTAG

Upstream 100 bases:

>100_bases
TTGACTGAGCCTCAAGCATATGACCCGACGTTCCCGTGTGGAGCGCTGATGGGAGGTGGTTAGTGGGTTGGGTGCCGGCT
GAACGGTAGAGTGGCCGAAC

Downstream 100 bases:

>100_bases
CTCTGGTTTGATACTTACTTGGCTTAACCGCATCTGAGATCCGTCATATCTTTGGCGTAGCCTTATTGGTATGAATAACA
TGCCGTAGCCAAAGGCCATC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MALTIGIVGLPNAGKSTLFNALTKNDVLAANYPFATIEPNVGVVGVPDKRLDVLTEMFHSAKTIPATVSFVDIAGIVKGA
SKGEGMGNEFLSNIREADAICQVTRCFADDDVTHVNGHVDPSDDIETITTELVLADLQTMEKQLPKLQKEAAIKKESRPK
VEAWEQAKAVLEEGKTIFSAGLDPEPLHDLFLLTTKPFIYVFNCDQDQLADADFQAKMEKLVAPAEAIFLDAEFEAELAE
MEPEDAAEFLADAGIEEPGLDKLARVGFDTLGLQTFLTAGEKESRAWTIHKGDTAPEAAGVIHTDFQKGFIKAQVVSFGD
LVEFGGEKEAQAAGKLRLEGKEYVMQDGDVVEFRFNV

Sequences:

>Translated_357_residues
MALTIGIVGLPNAGKSTLFNALTKNDVLAANYPFATIEPNVGVVGVPDKRLDVLTEMFHSAKTIPATVSFVDIAGIVKGA
SKGEGMGNEFLSNIREADAICQVTRCFADDDVTHVNGHVDPSDDIETITTELVLADLQTMEKQLPKLQKEAAIKKESRPK
VEAWEQAKAVLEEGKTIFSAGLDPEPLHDLFLLTTKPFIYVFNCDQDQLADADFQAKMEKLVAPAEAIFLDAEFEAELAE
MEPEDAAEFLADAGIEEPGLDKLARVGFDTLGLQTFLTAGEKESRAWTIHKGDTAPEAAGVIHTDFQKGFIKAQVVSFGD
LVEFGGEKEAQAAGKLRLEGKEYVMQDGDVVEFRFNV
>Mature_356_residues
ALTIGIVGLPNAGKSTLFNALTKNDVLAANYPFATIEPNVGVVGVPDKRLDVLTEMFHSAKTIPATVSFVDIAGIVKGAS
KGEGMGNEFLSNIREADAICQVTRCFADDDVTHVNGHVDPSDDIETITTELVLADLQTMEKQLPKLQKEAAIKKESRPKV
EAWEQAKAVLEEGKTIFSAGLDPEPLHDLFLLTTKPFIYVFNCDQDQLADADFQAKMEKLVAPAEAIFLDAEFEAELAEM
EPEDAAEFLADAGIEEPGLDKLARVGFDTLGLQTFLTAGEKESRAWTIHKGDTAPEAAGVIHTDFQKGFIKAQVVSFGDL
VEFGGEKEAQAAGKLRLEGKEYVMQDGDVVEFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=378, Percent_Identity=42.0634920634921, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI58761502, Length=183, Percent_Identity=38.7978142076503, Blast_Score=128, Evalue=8e-30,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=49.3112947658402, Blast_Score=356, Evalue=1e-99,
Organism=Escherichia coli, GI1789574, Length=171, Percent_Identity=29.8245614035088, Blast_Score=68, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=370, Percent_Identity=41.6216216216216, Blast_Score=278, Evalue=2e-75,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=40.1069518716578, Blast_Score=239, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6321773, Length=381, Percent_Identity=34.3832020997375, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6321649, Length=165, Percent_Identity=32.7272727272727, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640873, Length=371, Percent_Identity=42.3180592991914, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24640877, Length=371, Percent_Identity=42.3180592991914, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24640875, Length=371, Percent_Identity=42.3180592991914, Blast_Score=269, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24640879, Length=330, Percent_Identity=40.3030303030303, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24585318, Length=152, Percent_Identity=30.2631578947368, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38753; Mature: 38622

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTIGIVGLPNAGKSTLFNALTKNDVLAANYPFATIEPNVGVVGVPDKRLDVLTEMFHS
CEEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCCHHHHHHHHHHHC
AKTIPATVSFVDIAGIVKGASKGEGMGNEFLSNIREADAICQVTRCFADDDVTHVNGHVD
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
PSDDIETITTELVLADLQTMEKQLPKLQKEAAIKKESRPKVEAWEQAKAVLEEGKTIFSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEC
GLDPEPLHDLFLLTTKPFIYVFNCDQDQLADADFQAKMEKLVAPAEAIFLDAEFEAELAE
CCCCCCHHHEEEEECCCEEEEEECCHHHHCCCHHHHHHHHHHCCCHHEEECCHHHHHHHH
MEPEDAAEFLADAGIEEPGLDKLARVGFDTLGLQTFLTAGEKESRAWTIHKGDTAPEAAG
CCHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
VIHTDFQKGFIKAQVVSFGDLVEFGGEKEAQAAGKLRLEGKEYVMQDGDVVEFRFNV
CEEEHHHHCHHHHHHHHHHHHHHCCCCHHHHHCCCEEECCHHHEECCCCEEEEEECC
>Mature Secondary Structure 
ALTIGIVGLPNAGKSTLFNALTKNDVLAANYPFATIEPNVGVVGVPDKRLDVLTEMFHS
EEEEEEEECCCCCHHHHHHHHHCCCEEEECCCCEEECCCCCEEECCCHHHHHHHHHHHC
AKTIPATVSFVDIAGIVKGASKGEGMGNEFLSNIREADAICQVTRCFADDDVTHVNGHVD
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCC
PSDDIETITTELVLADLQTMEKQLPKLQKEAAIKKESRPKVEAWEQAKAVLEEGKTIFSA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEC
GLDPEPLHDLFLLTTKPFIYVFNCDQDQLADADFQAKMEKLVAPAEAIFLDAEFEAELAE
CCCCCCHHHEEEEECCCEEEEEECCHHHHCCCHHHHHHHHHHCCCHHEEECCHHHHHHHH
MEPEDAAEFLADAGIEEPGLDKLARVGFDTLGLQTFLTAGEKESRAWTIHKGDTAPEAAG
CCHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
VIHTDFQKGFIKAQVVSFGDLVEFGGEKEAQAAGKLRLEGKEYVMQDGDVVEFRFNV
CEEEHHHHCHHHHHHHHHHHHHHCCCCHHHHHCCCEEECCHHHEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA