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The map label for this gene is apeB [H]

Identifier: 50842060

GI number: 50842060

Start: 635181

End: 636467

Strand: Direct

Name: apeB [H]

Synonym: PPA0574

Alternate gene names: 50842060

Gene position: 635181-636467 (Clockwise)

Preceding gene: 50842058

Following gene: 50842061

Centisome position: 24.81

GC content: 61.62

Gene sequence:

>1287_bases
ATGGTCGTCATGGCTGACAAGAGCGTCCCGACTTCGGATCACATCCGCGACATCATCTCTTTCGTGGAAGCATCTCCCAC
CTCGTATCACGCTGTGGCGGAGCTGACGCGGCGGCTGGAGCAGGCCGGATTTCAGCGTCTAGAGGAGACCGAGTCGTGGC
CATCCGTCGAAGGGCGCCGGTACGTGGTGCGGGATGGAGCTGTCATCGCCTGGATCACTCCAGAGAAAGTGACTCCGCAG
CTGGGGGCGAGGATCGTCGGTTCCCATACCGACTCCCCGTCCTTCAAGCTTAAGCCGAACGCCACCGTTACTAACCAGGG
TTGGCAGCAGGTCGGTATGGAGGTCTACGGCGGTGGCCTACTGAATTCCTGGCTCGATCGTGATCTTGGGCTGTCCGGGC
GCCTCGTCACTTGCGACGGTCAGGCTCATTTAGTGCGAACCGGGCCGATTTTGCGCATCAGCCAGCTTGCGCCGCATCTG
GATCGCACCGTAAACGACGACCTCAAGCTGGACCGCCAGCGTCACCTCATGCCGATTCTGTCGGTCGGGAAGCCCGACCT
TGACGTTGAGGACCTGCTGTGTGAGGCGGCTGGGATCAAGCGCGACGAACTGGCCTTCCACGACGTTTTCGCCCATTTGA
CCCAGTCCCCGGCCGTCATCGGACCCTATGGGGAATTTCTAGCCAGCCAGCGTATGGACAATCTGTCTTCGGTTCACTCC
TCGGTCGCGGCATTCGTTGACGTCAAGCCGACCAGCGACGTGGCAGTCATGGCCTGCTTCGACCATGAAGAGGTCGGTTC
GGCGACAAGGTCGGGTGCCTGCGGGCCGTTCCTCGAGGACGTCTTGGTGCGCATCGCTGAGGGGTTCGGGATGACGGGTG
CGGCCTACCGGGCAATGATTGCCAAGTCCTCATGTGTGTCTTCAGATGCCGGGCACGGTGTGCATCCCAACTACGTTGAG
AAGTTCGATCCGGCGAATCACCCGCTGCTCAATGAGGGGCCATTACTCAAGATTAACGCTCATCAGCGTTATGCCACTGA
TGGCGTGGGTGGGGCTCTGTGGCAGCGGGCGTGCGCTGCTGCTGGGGTGCCGACCCAGAACTTCGTGTCGAATAACTCGG
TCCCGTGCGGCTCGACGATCGGGCCGCTGACGGCGACGAGGCTTGGCATGCTGACGGTTGACGTCGGAGTGCCGCTGATG
TCGATGCATTCCACTCGTGAACTTGCCGGTACGGCCGACCTGACGTACCTGTCCAAGGCGCTGGGGGCCTACTGGGCTGG
AGCCTGA

Upstream 100 bases:

>100_bases
GCCCGACCACGATGTTCGTCATGCCACGAGGGTCCCAGTAGGGTCTGACACATTCAGCCAGGGTCGTGTTTCGTCGTGAA
GAACAGCGGGTGATGGTTGA

Downstream 100 bases:

>100_bases
GCCGATTGGTTCCAAGTCCAGTCAATGTGCCGACAGTACTCGGCCACATTGACTGAGCCTCAAGCATATGACCCGACGTT
CCCGTGTGGAGCGCTGATGG

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MVVMADKSVPTSDHIRDIISFVEASPTSYHAVAELTRRLEQAGFQRLEETESWPSVEGRRYVVRDGAVIAWITPEKVTPQ
LGARIVGSHTDSPSFKLKPNATVTNQGWQQVGMEVYGGGLLNSWLDRDLGLSGRLVTCDGQAHLVRTGPILRISQLAPHL
DRTVNDDLKLDRQRHLMPILSVGKPDLDVEDLLCEAAGIKRDELAFHDVFAHLTQSPAVIGPYGEFLASQRMDNLSSVHS
SVAAFVDVKPTSDVAVMACFDHEEVGSATRSGACGPFLEDVLVRIAEGFGMTGAAYRAMIAKSSCVSSDAGHGVHPNYVE
KFDPANHPLLNEGPLLKINAHQRYATDGVGGALWQRACAAAGVPTQNFVSNNSVPCGSTIGPLTATRLGMLTVDVGVPLM
SMHSTRELAGTADLTYLSKALGAYWAGA

Sequences:

>Translated_428_residues
MVVMADKSVPTSDHIRDIISFVEASPTSYHAVAELTRRLEQAGFQRLEETESWPSVEGRRYVVRDGAVIAWITPEKVTPQ
LGARIVGSHTDSPSFKLKPNATVTNQGWQQVGMEVYGGGLLNSWLDRDLGLSGRLVTCDGQAHLVRTGPILRISQLAPHL
DRTVNDDLKLDRQRHLMPILSVGKPDLDVEDLLCEAAGIKRDELAFHDVFAHLTQSPAVIGPYGEFLASQRMDNLSSVHS
SVAAFVDVKPTSDVAVMACFDHEEVGSATRSGACGPFLEDVLVRIAEGFGMTGAAYRAMIAKSSCVSSDAGHGVHPNYVE
KFDPANHPLLNEGPLLKINAHQRYATDGVGGALWQRACAAAGVPTQNFVSNNSVPCGSTIGPLTATRLGMLTVDVGVPLM
SMHSTRELAGTADLTYLSKALGAYWAGA
>Mature_428_residues
MVVMADKSVPTSDHIRDIISFVEASPTSYHAVAELTRRLEQAGFQRLEETESWPSVEGRRYVVRDGAVIAWITPEKVTPQ
LGARIVGSHTDSPSFKLKPNATVTNQGWQQVGMEVYGGGLLNSWLDRDLGLSGRLVTCDGQAHLVRTGPILRISQLAPHL
DRTVNDDLKLDRQRHLMPILSVGKPDLDVEDLLCEAAGIKRDELAFHDVFAHLTQSPAVIGPYGEFLASQRMDNLSSVHS
SVAAFVDVKPTSDVAVMACFDHEEVGSATRSGACGPFLEDVLVRIAEGFGMTGAAYRAMIAKSSCVSSDAGHGVHPNYVE
KFDPANHPLLNEGPLLKINAHQRYATDGVGGALWQRACAAAGVPTQNFVSNNSVPCGSTIGPLTATRLGMLTVDVGVPLM
SMHSTRELAGTADLTYLSKALGAYWAGA

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=431, Percent_Identity=36.1948955916473, Blast_Score=273, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17552916, Length=464, Percent_Identity=32.3275862068966, Blast_Score=224, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6321905, Length=463, Percent_Identity=36.2850971922246, Blast_Score=283, Evalue=4e-77,
Organism=Saccharomyces cerevisiae, GI6322746, Length=453, Percent_Identity=27.8145695364238, Blast_Score=179, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 45965; Mature: 45965

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVMADKSVPTSDHIRDIISFVEASPTSYHAVAELTRRLEQAGFQRLEETESWPSVEGRR
CEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
YVVRDGAVIAWITPEKVTPQLGARIVGSHTDSPSFKLKPNATVTNQGWQQVGMEVYGGGL
EEEECCCEEEEECCCCCCHHHCCEEECCCCCCCCEEECCCCCCCCCCHHHHCHHHHCCHH
LNSWLDRDLGLSGRLVTCDGQAHLVRTGPILRISQLAPHLDRTVNDDLKLDRQRHLMPIL
HHHHHHHCCCCCCEEEEECCCEEEEECCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SVGKPDLDVEDLLCEAAGIKRDELAFHDVFAHLTQSPAVIGPYGEFLASQRMDNLSSVHS
HCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHH
SVAAFVDVKPTSDVAVMACFDHEEVGSATRSGACGPFLEDVLVRIAEGFGMTGAAYRAMI
HHHHEEECCCCCCEEEEEEECCHHHCCHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
AKSSCVSSDAGHGVHPNYVEKFDPANHPLLNEGPLLKINAHQRYATDGVGGALWQRACAA
HHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AGVPTQNFVSNNSVPCGSTIGPLTATRLGMLTVDVGVPLMSMHSTRELAGTADLTYLSKA
CCCCCHHHCCCCCCCCCCCCCCHHHHHHCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHH
LGAYWAGA
HHHHHCCC
>Mature Secondary Structure
MVVMADKSVPTSDHIRDIISFVEASPTSYHAVAELTRRLEQAGFQRLEETESWPSVEGRR
CEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
YVVRDGAVIAWITPEKVTPQLGARIVGSHTDSPSFKLKPNATVTNQGWQQVGMEVYGGGL
EEEECCCEEEEECCCCCCHHHCCEEECCCCCCCCEEECCCCCCCCCCHHHHCHHHHCCHH
LNSWLDRDLGLSGRLVTCDGQAHLVRTGPILRISQLAPHLDRTVNDDLKLDRQRHLMPIL
HHHHHHHCCCCCCEEEEECCCEEEEECCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHH
SVGKPDLDVEDLLCEAAGIKRDELAFHDVFAHLTQSPAVIGPYGEFLASQRMDNLSSVHS
HCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHH
SVAAFVDVKPTSDVAVMACFDHEEVGSATRSGACGPFLEDVLVRIAEGFGMTGAAYRAMI
HHHHEEECCCCCCEEEEEEECCHHHCCHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHH
AKSSCVSSDAGHGVHPNYVEKFDPANHPLLNEGPLLKINAHQRYATDGVGGALWQRACAA
HHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
AGVPTQNFVSNNSVPCGSTIGPLTATRLGMLTVDVGVPLMSMHSTRELAGTADLTYLSKA
CCCCCHHHCCCCCCCCCCCCCCHHHHHHCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHH
LGAYWAGA
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]