| Definition | Propionibacterium acnes KPA171202, complete genome. |
|---|---|
| Accession | NC_006085 |
| Length | 2,560,265 |
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The map label for this gene is yxbG [H]
Identifier: 50841629
GI number: 50841629
Start: 168440
End: 169240
Strand: Direct
Name: yxbG [H]
Synonym: PPA0140
Alternate gene names: 50841629
Gene position: 168440-169240 (Clockwise)
Preceding gene: 50841628
Following gene: 50841634
Centisome position: 6.58
GC content: 61.55
Gene sequence:
>801_bases ATGGATCTTGGACTCAACGGACGCACTGCGCTCATCACTGGCGCTGATTCGGGTATTGGCTGGCACACCGCGAAACTCCT CCTCGCCGAGGGAGCCAAAGTTGCCATCACCGACCTCGACTCTGACGAACTCACCCAGGCTGCGCAGGCTCTCGACGTCG CTGATGACCGTCTCGTCGCCCTCCCGGCCGACGTCACTGACGCTGACTCTCTGGCGAAGCTGCACCAGCAAGTGAAGGAC GCCCTCGGTCCGATTGACATCCTCGTCCAGTCGGCCGGCGTGACCGGGGCCCAGGGTAAGTTCCACGAGATCGATGAGGA GGGCTGGCGTTCCACCCTTGACATTGACCTCATGGGTCCGGTGCGGGTGCTGCGCGAGTTCCTCGATGACTTGCGCACGG GTGGCTGGGGGCGTGTCGTGCTGCTGGCCTCTGAGGACGGCGTCCAGCCCTACGACGACGAGATCCCCTACTGCGCTGCC AAGGCCGGAGTATTGGCTCTGGCTAAGGGTTTGTCGCGGACCTATGCCCGTGAAGGACTCCTCGTCAACGCCGTTTCTCC AGCCTTCATCCATACCCCGATGACTGACGCCATGATGAATAAGCGGTCCAAGGAGCTTGGCGTTAGCTTTGACGAGGCCA TCGAGTCCTTCCTTGACCAGGAGCGCCCCTATATGGAGCTCAAACGGCGCGGCGAGCCTGAGGAGGTGGCTGCCGTCATC GCTTTCCTATGTTCGGACAAGGCTTCCTTCGTTAACGGATCGAACTACCGCGTCGACTCCGGATCGGTGGCCACTTTTTG A
Upstream 100 bases:
>100_bases GCTGTGGAACCTTCCCGGACGCACCGACAAGGCCGTCACAGTGCTTGCCGATCCGCCTGAGGACCTCTCGACCGCTATCA GCTAACCACTAGGAGGAATC
Downstream 100 bases:
>100_bases GGTTCGACATTGGTGCCTGTGGGGCCGAGTCACGATGGCAGCGGCCCCATCGTGGAGGCTGGCTCAGGCGTCGAGGTTAG AGGCAACCAGGTCGGCAATG
Product: putative ketoacyl reductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 266; Mature: 266
Protein sequence:
>266_residues MDLGLNGRTALITGADSGIGWHTAKLLLAEGAKVAITDLDSDELTQAAQALDVADDRLVALPADVTDADSLAKLHQQVKD ALGPIDILVQSAGVTGAQGKFHEIDEEGWRSTLDIDLMGPVRVLREFLDDLRTGGWGRVVLLASEDGVQPYDDEIPYCAA KAGVLALAKGLSRTYAREGLLVNAVSPAFIHTPMTDAMMNKRSKELGVSFDEAIESFLDQERPYMELKRRGEPEEVAAVI AFLCSDKASFVNGSNYRVDSGSVATF
Sequences:
>Translated_266_residues MDLGLNGRTALITGADSGIGWHTAKLLLAEGAKVAITDLDSDELTQAAQALDVADDRLVALPADVTDADSLAKLHQQVKD ALGPIDILVQSAGVTGAQGKFHEIDEEGWRSTLDIDLMGPVRVLREFLDDLRTGGWGRVVLLASEDGVQPYDDEIPYCAA KAGVLALAKGLSRTYAREGLLVNAVSPAFIHTPMTDAMMNKRSKELGVSFDEAIESFLDQERPYMELKRRGEPEEVAAVI AFLCSDKASFVNGSNYRVDSGSVATF >Mature_266_residues MDLGLNGRTALITGADSGIGWHTAKLLLAEGAKVAITDLDSDELTQAAQALDVADDRLVALPADVTDADSLAKLHQQVKD ALGPIDILVQSAGVTGAQGKFHEIDEEGWRSTLDIDLMGPVRVLREFLDDLRTGGWGRVVLLASEDGVQPYDDEIPYCAA KAGVLALAKGLSRTYAREGLLVNAVSPAFIHTPMTDAMMNKRSKELGVSFDEAIESFLDQERPYMELKRRGEPEEVAAVI AFLCSDKASFVNGSNYRVDSGSVATF
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=27.5193798449612, Blast_Score=111, Evalue=7e-25, Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=29.5019157088123, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI31542939, Length=223, Percent_Identity=28.6995515695067, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI5031737, Length=254, Percent_Identity=27.9527559055118, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI19923817, Length=270, Percent_Identity=30, Blast_Score=96, Evalue=5e-20, Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=25.4752851711027, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI223718074, Length=248, Percent_Identity=29.8387096774194, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=32.2033898305085, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4758504, Length=268, Percent_Identity=26.1194029850746, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=25.1968503937008, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI7705925, Length=265, Percent_Identity=27.1698113207547, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI4503817, Length=196, Percent_Identity=26.0204081632653, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4504505, Length=270, Percent_Identity=25.5555555555556, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI59889578, Length=241, Percent_Identity=28.2157676348548, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI83715985, Length=268, Percent_Identity=25.7462686567164, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=27.0718232044199, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=23.6434108527132, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=27.6595744680851, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI20149619, Length=197, Percent_Identity=24.3654822335025, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI40807363, Length=232, Percent_Identity=22.4137931034483, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=33.5907335907336, Blast_Score=124, Evalue=5e-30, Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=31.2741312741313, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI1789378, Length=259, Percent_Identity=29.3436293436293, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=27.2030651340996, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=30.5555555555556, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=27.906976744186, Blast_Score=87, Evalue=9e-19, Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=29.5719844357977, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=28.125, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787905, Length=262, Percent_Identity=25.5725190839695, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=26.2357414448669, Blast_Score=79, Evalue=4e-16, Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=31.6602316602317, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=27.6264591439689, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=3e-22, Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=32.046332046332, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538182, Length=267, Percent_Identity=28.0898876404494, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=29.296875, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=28.125, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=29.0566037735849, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=29.2134831460674, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=27.1698113207547, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=26.8041237113402, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=26.8939393939394, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=23.2, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=27.8388278388278, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=26.4705882352941, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=28.5185185185185, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=27.0676691729323, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=27.7777777777778, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=28.5171102661597, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=27.7566539923954, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=27.6515151515151, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=27.0676691729323, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=27.6119402985075, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17536025, Length=269, Percent_Identity=29.368029739777, Blast_Score=74, Evalue=6e-14, Organism=Caenorhabditis elegans, GI115534694, Length=255, Percent_Identity=25.8823529411765, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=27.6679841897233, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=25.2747252747253, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=27.4611398963731, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17536651, Length=269, Percent_Identity=27.5092936802974, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI115534660, Length=213, Percent_Identity=28.169014084507, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17564282, Length=198, Percent_Identity=25.7575757575758, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI193203117, Length=201, Percent_Identity=25.8706467661692, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193203115, Length=199, Percent_Identity=25.6281407035176, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=269, Percent_Identity=25.6505576208178, Blast_Score=66, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=27.6923076923077, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI23397609, Length=260, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24639444, Length=265, Percent_Identity=31.3207547169811, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=26.5060240963855, Blast_Score=94, Evalue=9e-20, Organism=Drosophila melanogaster, GI17737361, Length=266, Percent_Identity=27.0676691729323, Blast_Score=88, Evalue=7e-18, Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI18859837, Length=250, Percent_Identity=26.4, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=28.2442748091603, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI21356301, Length=192, Percent_Identity=26.0416666666667, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=27.8947368421053, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24644337, Length=273, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 28566; Mature: 28566
Theoretical pI: Translated: 4.31; Mature: 4.31
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLGLNGRTALITGADSGIGWHTAKLLLAEGAKVAITDLDSDELTQAAQALDVADDRLVA CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCEEE LPADVTDADSLAKLHQQVKDALGPIDILVQSAGVTGAQGKFHEIDEEGWRSTLDIDLMGP ECCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHCCHHHCCEEEEEECCCH VRVLREFLDDLRTGGWGRVVLLASEDGVQPYDDEIPYCAAKAGVLALAKGLSRTYAREGL HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCE LVNAVSPAFIHTPMTDAMMNKRSKELGVSFDEAIESFLDQERPYMELKRRGEPEEVAAVI EEECCCCHHEECCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHH AFLCSDKASFVNGSNYRVDSGSVATF HHHHCCCHHHCCCCCEEECCCCCCCC >Mature Secondary Structure MDLGLNGRTALITGADSGIGWHTAKLLLAEGAKVAITDLDSDELTQAAQALDVADDRLVA CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCCCEEE LPADVTDADSLAKLHQQVKDALGPIDILVQSAGVTGAQGKFHEIDEEGWRSTLDIDLMGP ECCCCCCHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHCCHHHCCEEEEEECCCH VRVLREFLDDLRTGGWGRVVLLASEDGVQPYDDEIPYCAAKAGVLALAKGLSRTYAREGL HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCE LVNAVSPAFIHTPMTDAMMNKRSKELGVSFDEAIESFLDQERPYMELKRRGEPEEVAAVI EEECCCCHHEECCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHH AFLCSDKASFVNGSNYRVDSGSVATF HHHHCCCHHHCCCCCEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7584049; 9384377 [H]