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The map label for this gene is dtpT [H]

Identifier: 50841627

GI number: 50841627

Start: 165419

End: 166996

Strand: Direct

Name: dtpT [H]

Synonym: PPA0138

Alternate gene names: 50841627

Gene position: 165419-166996 (Clockwise)

Preceding gene: 50841626

Following gene: 50841628

Centisome position: 6.46

GC content: 59.32

Gene sequence:

>1578_bases
ATGTCCCTCGAACCGCTTGATGTCGACGCGGAAGGCGTCGCCGCCGCCACCAAAGCACGAGGTTTTCGGCCTAAGCATCT
GGTGACAGGACCCTCGCGTGACGACAAGTCATTCTTGGGCCACCCCGGCGGTTTGCCGTGGATGCTCCAGGTAGAAATGT
GGGAGCGGTTCTCGTGGTATGGCATGCGCGCCATCCTCGTCTACTTCATCACCGACACTTTGGCCCATGGCGGGCTGGGA
TTGCCGATCAACGCCGGCCAGGTTGTTATGGCTTCCTACGGCGCCGCAGTGTTGTTGATGACGATTCCTGGCGGTATCTT
TGCTGACCGCATCCTCGGGCCGTGGATGTCCACCCTGTGCGGCGGTCTCATCATCATGACGGGTCACGTCATCCTGGCGA
TCCCGCAGGTGGTGACGTCATGGATCGGCCTCATCTGCATCGCCATTGGCACGGGTTTTATCAAGCCGAACCTCTCCACG
GTGGTAGGAGGTCTCTACGATGACGGCGACCCCCGCCGCGATCAAGGTTTCCTGTACTTCTACATGTCGATCAATATTGG
ATCTCTCTTCGCGCCGATCGTCACCGGCCTCCTCAAGGACCATTACGGCTACCACGTAGGTTTCATTGCCGCTGCTATCG
GTATGGCTCTGGGGCTGATCGCCTTCTTCCACGGTCGTTCCAAACTGCGTGAGTTCGCCTTCGACATCCCTAATCCGCTG
GCCCCCGGCGAGGGTCGCCGGATGGTGCTCCGCGCGTTGGGTATTGCCGTCGTCGGTGCCGTCCTTGCCATCGGTTTCAA
AGCCTTGCTGGGCGAGTGGACCTCGGCCATCGCCTACGCTCTGTTCGCCTTTGCCTCGGTGACGGCACTGAGCTACTTCT
TGACGATGTTCCGCTCCCCGAAGGTCTCTGATCGTGAGCGTGGCCATTTATGGGCATTTGTGCCGTTGTGGGTTGGCCAA
GTGCTGTTCACCATGATCTTCGAGCAGGCGGCCGGCAAGATGCCCACCTTTGCTAAGGACAACACCGACGGCCACATCGT
CGGGTCGTGGTCGGTGGAGCCTGAGCAGTACCAAACCATTAACCCGGCTGCAGTCTTGATCCTGGCTGGCCTGCTAGGCA
TGTGGTTCCGGCGCAGAGAAGGGAAGTTCCCCAATACCCCGCAGAAGTTCGCCATTTCGGTGTTCATCATTGGTATAACC
GCCCTCATTATGGGATTCGGTTTCCGGAGTTGGCCAGGTGGGAACAGACTCGCACCGTGGTGGTTCCTGGCGGTGGTGTT
CGTCATTCAGACTGTTGCTGAGCTGTTCATGAACCCGATCGGTTTGTCGACCGCGACCAAGCTAGCCCCGAAAAAGTTCG
CATCCCAGAACATGACCCTGTGGCTGCTCGCCTCAGCCTGTGGCCAGGGCCTCGCCTCGGTGACGATCGAGCGCACCAAG
AACCTTGGTGACGTGGTGTTCTACTACAGCCTAGGTATCGTGACGATCCTTGTAGCGGTGGTGCTCTTCGTGATCGCCCC
ATGGACCCAGGCGAAGATGAAGGATGTCGACTCCGTTGCCGAGGAGGGTGACGCCTGA

Upstream 100 bases:

>100_bases
CACCACTGTCTAGGCACAGGTCGGTCATCCCCTGGGGGAGTTCCGAACCATTGTCTTGGAGGACCTCGTGGTGCCTCATA
ACATCGGAAAGGAAGGGAAA

Downstream 100 bases:

>100_bases
CCTCACTCCCAACCCATTGCGAGGTCCGTCCCGTTTGGGGTGGGCCTCGTGCCTTGTCAGGGGGTTTACGCGTGGTGTGG
TAATCCGGTTTCTGGTGGCG

Product: dipeptide/tripeptide permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MSLEPLDVDAEGVAAATKARGFRPKHLVTGPSRDDKSFLGHPGGLPWMLQVEMWERFSWYGMRAILVYFITDTLAHGGLG
LPINAGQVVMASYGAAVLLMTIPGGIFADRILGPWMSTLCGGLIIMTGHVILAIPQVVTSWIGLICIAIGTGFIKPNLST
VVGGLYDDGDPRRDQGFLYFYMSINIGSLFAPIVTGLLKDHYGYHVGFIAAAIGMALGLIAFFHGRSKLREFAFDIPNPL
APGEGRRMVLRALGIAVVGAVLAIGFKALLGEWTSAIAYALFAFASVTALSYFLTMFRSPKVSDRERGHLWAFVPLWVGQ
VLFTMIFEQAAGKMPTFAKDNTDGHIVGSWSVEPEQYQTINPAAVLILAGLLGMWFRRREGKFPNTPQKFAISVFIIGIT
ALIMGFGFRSWPGGNRLAPWWFLAVVFVIQTVAELFMNPIGLSTATKLAPKKFASQNMTLWLLASACGQGLASVTIERTK
NLGDVVFYYSLGIVTILVAVVLFVIAPWTQAKMKDVDSVAEEGDA

Sequences:

>Translated_525_residues
MSLEPLDVDAEGVAAATKARGFRPKHLVTGPSRDDKSFLGHPGGLPWMLQVEMWERFSWYGMRAILVYFITDTLAHGGLG
LPINAGQVVMASYGAAVLLMTIPGGIFADRILGPWMSTLCGGLIIMTGHVILAIPQVVTSWIGLICIAIGTGFIKPNLST
VVGGLYDDGDPRRDQGFLYFYMSINIGSLFAPIVTGLLKDHYGYHVGFIAAAIGMALGLIAFFHGRSKLREFAFDIPNPL
APGEGRRMVLRALGIAVVGAVLAIGFKALLGEWTSAIAYALFAFASVTALSYFLTMFRSPKVSDRERGHLWAFVPLWVGQ
VLFTMIFEQAAGKMPTFAKDNTDGHIVGSWSVEPEQYQTINPAAVLILAGLLGMWFRRREGKFPNTPQKFAISVFIIGIT
ALIMGFGFRSWPGGNRLAPWWFLAVVFVIQTVAELFMNPIGLSTATKLAPKKFASQNMTLWLLASACGQGLASVTIERTK
NLGDVVFYYSLGIVTILVAVVLFVIAPWTQAKMKDVDSVAEEGDA
>Mature_524_residues
SLEPLDVDAEGVAAATKARGFRPKHLVTGPSRDDKSFLGHPGGLPWMLQVEMWERFSWYGMRAILVYFITDTLAHGGLGL
PINAGQVVMASYGAAVLLMTIPGGIFADRILGPWMSTLCGGLIIMTGHVILAIPQVVTSWIGLICIAIGTGFIKPNLSTV
VGGLYDDGDPRRDQGFLYFYMSINIGSLFAPIVTGLLKDHYGYHVGFIAAAIGMALGLIAFFHGRSKLREFAFDIPNPLA
PGEGRRMVLRALGIAVVGAVLAIGFKALLGEWTSAIAYALFAFASVTALSYFLTMFRSPKVSDRERGHLWAFVPLWVGQV
LFTMIFEQAAGKMPTFAKDNTDGHIVGSWSVEPEQYQTINPAAVLILAGLLGMWFRRREGKFPNTPQKFAISVFIIGITA
LIMGFGFRSWPGGNRLAPWWFLAVVFVIQTVAELFMNPIGLSTATKLAPKKFASQNMTLWLLASACGQGLASVTIERTKN
LGDVVFYYSLGIVTILVAVVLFVIAPWTQAKMKDVDSVAEEGDA

Specific function: Proton-dependent uptake of di- or tri-peptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=224, Percent_Identity=29.4642857142857, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI226371746, Length=203, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1787922, Length=490, Percent_Identity=25.7142857142857, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789911, Length=488, Percent_Identity=25.8196721311475, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1790572, Length=449, Percent_Identity=28.9532293986637, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786927, Length=455, Percent_Identity=27.2527472527473, Blast_Score=146, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71987453, Length=367, Percent_Identity=28.6103542234332, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17569141, Length=221, Percent_Identity=28.9592760180996, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571102, Length=398, Percent_Identity=24.6231155778894, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571100, Length=398, Percent_Identity=24.6231155778894, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571098, Length=350, Percent_Identity=26.2857142857143, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24639585, Length=343, Percent_Identity=26.530612244898, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639583, Length=343, Percent_Identity=26.530612244898, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639581, Length=343, Percent_Identity=26.530612244898, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 57014; Mature: 56883

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEPLDVDAEGVAAATKARGFRPKHLVTGPSRDDKSFLGHPGGLPWMLQVEMWERFSWY
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEHHHHHHHHHH
GMRAILVYFITDTLAHGGLGLPINAGQVVMASYGAAVLLMTIPGGIFADRILGPWMSTLC
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHHH
GGLIIMTGHVILAIPQVVTSWIGLICIAIGTGFIKPNLSTVVGGLYDDGDPRRDQGFLYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCEEEE
YMSINIGSLFAPIVTGLLKDHYGYHVGFIAAAIGMALGLIAFFHGRSKLREFAFDIPNPL
EEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APGEGRRMVLRALGIAVVGAVLAIGFKALLGEWTSAIAYALFAFASVTALSYFLTMFRSP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KVSDRERGHLWAFVPLWVGQVLFTMIFEQAAGKMPTFAKDNTDGHIVGSWSVEPEQYQTI
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHCCC
NPAAVLILAGLLGMWFRRREGKFPNTPQKFAISVFIIGITALIMGFGFRSWPGGNRLAPW
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
WFLAVVFVIQTVAELFMNPIGLSTATKLAPKKFASQNMTLWLLASACGQGLASVTIERTK
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHHC
NLGDVVFYYSLGIVTILVAVVLFVIAPWTQAKMKDVDSVAEEGDA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLEPLDVDAEGVAAATKARGFRPKHLVTGPSRDDKSFLGHPGGLPWMLQVEMWERFSWY
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCEEEEHHHHHHHHHH
GMRAILVYFITDTLAHGGLGLPINAGQVVMASYGAAVLLMTIPGGIFADRILGPWMSTLC
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCEEEEEECCCHHHHHHHHHHHHHHHH
GGLIIMTGHVILAIPQVVTSWIGLICIAIGTGFIKPNLSTVVGGLYDDGDPRRDQGFLYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCEEEE
YMSINIGSLFAPIVTGLLKDHYGYHVGFIAAAIGMALGLIAFFHGRSKLREFAFDIPNPL
EEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APGEGRRMVLRALGIAVVGAVLAIGFKALLGEWTSAIAYALFAFASVTALSYFLTMFRSP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KVSDRERGHLWAFVPLWVGQVLFTMIFEQAAGKMPTFAKDNTDGHIVGSWSVEPEQYQTI
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCHHHHCCC
NPAAVLILAGLLGMWFRRREGKFPNTPQKFAISVFIIGITALIMGFGFRSWPGGNRLAPW
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
WFLAVVFVIQTVAELFMNPIGLSTATKLAPKKFASQNMTLWLLASACGQGLASVTIERTK
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHCCCHHHHHHHHHC
NLGDVVFYYSLGIVTILVAVVLFVIAPWTQAKMKDVDSVAEEGDA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]