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The map label for this gene is ycbL [H]

Identifier: 50086246

GI number: 50086246

Start: 3166832

End: 3167479

Strand: Reverse

Name: ycbL [H]

Synonym: ACIAD3254

Alternate gene names: 50086246

Gene position: 3167479-3166832 (Counterclockwise)

Preceding gene: 50086247

Following gene: 50086242

Centisome position: 88.02

GC content: 43.83

Gene sequence:

>648_bases
TTGATGTTGCAAGTAAAAATTGTTCCTGTAACAGCATTTGCCCAAAACTGTTCGATTTTGTGGGACAGTGAATCAAAAGA
AGCCGTATTAATTGATGCAGGCGGAGAGGCCGTTAAGCTTAAACAGGAGGTTGAAGCGATGGGGCTAAAGGTCAAGGCAT
TGTGGTTGACACACGGGCATCTAGATCATGCGGGAGCAGTGGGTGAATTAGCTAAACTTTGGCAGGTTCCTGTGATTGGT
CCGCATAAAGATGATCAGTTCTGGCTAGATATGATTCAGGATGTGTCAAAGCGTTACGGATTTCCGATTCCACAGCCTGT
ACAGGTTGATACTTGGCTAGAAGGTGGCGAAATACTAGAGCTGGGACAGACAAAGTTTGAGGTGAGATTTGCACCAGGGC
ATACGCCAGGTCATGTCATGTTTTACAGCCCAGAATATCATCTGTTATGGACAGGAGACGTATTGTTTAAAGGATCAATT
GGACGTACAGACTTTCCTCGAGGCAATCATCAACAATTGATTGACTCAATTCAACGTGAATGTTTTAGCTTACCTGATGA
AACGCAGTTTATTTCTGGCCATGGCCCTATGAGCACGATTGGTCATGAAAAAAAGTTTAATCCTTTTGTGGCAGGAAAAG
CAGGTTAG

Upstream 100 bases:

>100_bases
TTCCGTTGAGCATCTGGAGCTATTGCGTCAATTGTTACAGGCACATCTGGATGCACTCAATTACAGTCTGGCCTATTCGG
CACATTAATTTAAGGAGAAT

Downstream 100 bases:

>100_bases
GGTATGTGTAGATTAAATGCTTATGGATTAGGATTTGATGGTTCAAGGATTACAGATAGATTCGAGCTCTTCAACCACAA
ATTTGATCATGAGCATGAAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MMLQVKIVPVTAFAQNCSILWDSESKEAVLIDAGGEAVKLKQEVEAMGLKVKALWLTHGHLDHAGAVGELAKLWQVPVIG
PHKDDQFWLDMIQDVSKRYGFPIPQPVQVDTWLEGGEILELGQTKFEVRFAPGHTPGHVMFYSPEYHLLWTGDVLFKGSI
GRTDFPRGNHQQLIDSIQRECFSLPDETQFISGHGPMSTIGHEKKFNPFVAGKAG

Sequences:

>Translated_215_residues
MMLQVKIVPVTAFAQNCSILWDSESKEAVLIDAGGEAVKLKQEVEAMGLKVKALWLTHGHLDHAGAVGELAKLWQVPVIG
PHKDDQFWLDMIQDVSKRYGFPIPQPVQVDTWLEGGEILELGQTKFEVRFAPGHTPGHVMFYSPEYHLLWTGDVLFKGSI
GRTDFPRGNHQQLIDSIQRECFSLPDETQFISGHGPMSTIGHEKKFNPFVAGKAG
>Mature_215_residues
MMLQVKIVPVTAFAQNCSILWDSESKEAVLIDAGGEAVKLKQEVEAMGLKVKALWLTHGHLDHAGAVGELAKLWQVPVIG
PHKDDQFWLDMIQDVSKRYGFPIPQPVQVDTWLEGGEILELGQTKFEVRFAPGHTPGHVMFYSPEYHLLWTGDVLFKGSI
GRTDFPRGNHQQLIDSIQRECFSLPDETQFISGHGPMSTIGHEKKFNPFVAGKAG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=195, Percent_Identity=32.3076923076923, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1787158, Length=208, Percent_Identity=49.0384615384615, Blast_Score=224, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17538952, Length=195, Percent_Identity=28.7179487179487, Blast_Score=77, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23944; Mature: 23944

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLQVKIVPVTAFAQNCSILWDSESKEAVLIDAGGEAVKLKQEVEAMGLKVKALWLTHGH
CEEEEEEEEEEEECCCCEEEECCCCCCEEEEECCCCEEEHHHHHHHHCEEEEEEEEECCC
LDHAGAVGELAKLWQVPVIGPHKDDQFWLDMIQDVSKRYGFPIPQPVQVDTWLEGGEILE
CCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEE
LGQTKFEVRFAPGHTPGHVMFYSPEYHLLWTGDVLFKGSIGRTDFPRGNHQQLIDSIQRE
ECCCEEEEEECCCCCCCEEEEECCCEEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHH
CFSLPDETQFISGHGPMSTIGHEKKFNPFVAGKAG
HHCCCCCCEEEECCCCHHHCCCCCCCCCEECCCCC
>Mature Secondary Structure
MMLQVKIVPVTAFAQNCSILWDSESKEAVLIDAGGEAVKLKQEVEAMGLKVKALWLTHGH
CEEEEEEEEEEEECCCCEEEECCCCCCEEEEECCCCEEEHHHHHHHHCEEEEEEEEECCC
LDHAGAVGELAKLWQVPVIGPHKDDQFWLDMIQDVSKRYGFPIPQPVQVDTWLEGGEILE
CCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEE
LGQTKFEVRFAPGHTPGHVMFYSPEYHLLWTGDVLFKGSIGRTDFPRGNHQQLIDSIQRE
ECCCEEEEEECCCCCCCEEEEECCCEEEEEECCEEEECCCCCCCCCCCCHHHHHHHHHHH
CFSLPDETQFISGHGPMSTIGHEKKFNPFVAGKAG
HHCCCCCCEEEECCCCHHHCCCCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]