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The map label for this gene is accA [H]

Identifier: 50086048

GI number: 50086048

Start: 2964663

End: 2965487

Strand: Reverse

Name: accA [H]

Synonym: ACIAD3035

Alternate gene names: 50086048

Gene position: 2965487-2964663 (Counterclockwise)

Preceding gene: 50086049

Following gene: 50086047

Centisome position: 82.41

GC content: 45.94

Gene sequence:

>825_bases
ATGAAAAATAAAGCTGCTCAGTCTAAAGCGTGGACAACGGTTCAAATTGCACGACATCCAGATCGTCCGCAATTCTTAGA
TTATGTCGGAGAAATTTTCACCGAATTTGATGCTTTACATGGTGATCGTCTGTTTGGTGATGACGGTGCGATGGTGGGTG
GTTTAGCTCGCTTTGAAGGTCAACCTGTGATGGTGGTTGGTCAACACCGTGGTCGTAGTACACGTGAGAAGCTCAAGCAC
AACTTTGGTATGTGTAATCCTGAAGGCTATCGTAAATCGCAACGTTTGCTTGATATGGCTGAGCGTTTTAATCTACCTGT
ATTTACGTTTATCGATACCATGGGTGCATATCCAGGTGTCGGCGCTGAAGAACGTGGTCAGGCAGAAGCGATTGCGACCA
GTCTTGCACAGCTATCGAGCCTTAAAGTGCCTGTCATTGCGACAGTACTGGGTGAAGGTGGTTCTGGTGGTGCATTAGGT
ATCGGTGTTGCCGATCGTGTCGTGATGTTGTCTCACAGCATCTATTCTGTGATCTCTCCAGAAGGCTGCGCTACAATCTT
GTGGAAAACTGCTGAAAAAGCTGAGCAAGCCAGCAATGCATTGGCATTGACAGCAGATAAACTGCAAAAGATTGGTATCG
TTGAATACGTAGTCGATGAAGGCGAAGGTGCGCATTTACATCCAGAACAGGTTATGCAAAATCTTCAAGTCGTGTTAAAA
CAGGCGCTAGATGAATTGCTTGCTATGGATGCAGATGAACGATGCGAAGCGCGTTACCAACGTTTGATGAAATTTGGCAG
CGAAAATTTAGGCATCGCCTCTTAA

Upstream 100 bases:

>100_bases
AGCAAGAGCAATTTAAGCACTGGGACATTGAGTTGAATATTCAGTCGGAAAAATTTATCGATTAACTCGATTTGGTTAAT
TTAGGGATAATGCTCGACTT

Downstream 100 bases:

>100_bases
TACAGGCTCAGCAATTTCCTGCTGATACCGTATTCTTAATTGGATGCAGCGGTGGCATGGATTCCATGTTATTGCTGCAT
TTGATGTCGGAACTGTTTCC

Product: acetyl-coenzyme A carboxylase carboxyl transferase alpha subunit

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKNKAAQSKAWTTVQIARHPDRPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFEGQPVMVVGQHRGRSTREKLKH
NFGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALG
IGVADRVVMLSHSIYSVISPEGCATILWKTAEKAEQASNALALTADKLQKIGIVEYVVDEGEGAHLHPEQVMQNLQVVLK
QALDELLAMDADERCEARYQRLMKFGSENLGIAS

Sequences:

>Translated_274_residues
MKNKAAQSKAWTTVQIARHPDRPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFEGQPVMVVGQHRGRSTREKLKH
NFGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALG
IGVADRVVMLSHSIYSVISPEGCATILWKTAEKAEQASNALALTADKLQKIGIVEYVVDEGEGAHLHPEQVMQNLQVVLK
QALDELLAMDADERCEARYQRLMKFGSENLGIAS
>Mature_274_residues
MKNKAAQSKAWTTVQIARHPDRPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFEGQPVMVVGQHRGRSTREKLKH
NFGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALG
IGVADRVVMLSHSIYSVISPEGCATILWKTAEKAEQASNALALTADKLQKIGIVEYVVDEGEGAHLHPEQVMQNLQVVLK
QALDELLAMDADERCEARYQRLMKFGSENLGIAS

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=258, Percent_Identity=55.0387596899225, Blast_Score=302, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 29792; Mature: 29792

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKAAQSKAWTTVQIARHPDRPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFEG
CCCCHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCC
QPVMVVGQHRGRSTREKLKHNFGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTMGAYPGV
CCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
GAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVVMLSHSIYSVISP
CCCCCCHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCC
EGCATILWKTAEKAEQASNALALTADKLQKIGIVEYVVDEGEGAHLHPEQVMQNLQVVLK
CCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
QALDELLAMDADERCEARYQRLMKFGSENLGIAS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKNKAAQSKAWTTVQIARHPDRPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFEG
CCCCHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHCC
QPVMVVGQHRGRSTREKLKHNFGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTMGAYPGV
CCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
GAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVVMLSHSIYSVISP
CCCCCCHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHCC
EGCATILWKTAEKAEQASNALALTADKLQKIGIVEYVVDEGEGAHLHPEQVMQNLQVVLK
CCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
QALDELLAMDADERCEARYQRLMKFGSENLGIAS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA