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The map label for this gene is aro [H]

Identifier: 50085019

GI number: 50085019

Start: 1870386

End: 1871441

Strand: Reverse

Name: aro [H]

Synonym: ACIAD1878

Alternate gene names: 50085019

Gene position: 1871441-1870386 (Counterclockwise)

Preceding gene: 50085020

Following gene: 50085014

Centisome position: 52.0

GC content: 40.15

Gene sequence:

>1056_bases
ATGAACGCGCTTAATACATTGATCCAGAAAAATACGACAAAAGAAATTACACTTAGCTTGCCACAGCAATTAAAAGCAAA
ATATTCGCTTGCTCCCATTTTTTTAGAGCAGATCGCAGAGCATCGTCAAACCATTCAAAATATCCTTGCTGGCAAAGATT
CACGGCTTTTGGTCGTAACTGGTCCATGTTCGATTCATGATCCTGTTTCTGCGCTGCAATACGCACAAAGGCTTGTCAAA
TTACAAGATCAAGTTAAAGATCAGATTTTTTTAGTGATGCGTGCTTATCTCGAAAAACCACGTACAACAATTGGCTGGAA
GGGTTTTTTATACGATCCAAATCTTGATGGTTCATCAGATTTACAGCTGGGTTTAGAAAAATCTCGCGCATTATATTTGC
AAATTATTGAAATGGGGCTTCCAATTGCCAGTGAAATTTTAAGCCCAATGGCGACTGGCTATTTTGATGATTTACTGGCT
TGGGGAGCTATTGGGGCACGTACCAGTGAATCTCAGATTCATCGTGAAATTTCAAGTCATATGCCGTTTCCAATTGGTTT
TAAAAATGGTACTGATGGTTCGATTCAGATCGCATTGGATGCCATTCAATCTGCACAAAATGAACATCAGTTTTTAGGGA
TGAGTCAGCTTGGCCAGCCTGCAATTTTACAAAGTTCTGGGAATCCACTGCCGCATTTGATCTTGCGTGGAGCAAATGAT
GGACCAAATTATGATATTCAGTCCATTTCGAATATTAGAGCAAAACATAAGGGCGAATTACCTGCGCTTGTAATTGACTG
TAGTCATGGCAATAGTTCAAAAGATCCGATGAAACAACCGCAAGTACTTCGACAAATCATTGCAGAAAGAATTGAAAGTG
ATGTTCGAGGTGTGATGTTGGAAAGCCATTTGGTCGATGGAAATCAGAAGATTTCATGCGACATAACCTATGGCCAATCT
GTGACTGATGGTTGCCTTGGGTGGGAGAAGACAGAGAATTTACTTTTAGAAATGGCTGATCAACTCGCACAATGTCCTTT
ACGCCAATCAGCTTAA

Upstream 100 bases:

>100_bases
ACGTGGATTACTTTTACTTTAATCAACATCTTCAACTGAATAGATCCTCATTGCTCAAATAAATGATCGGGCTGATTGAG
ACAGCCCAAAGGAATATGAA

Downstream 100 bases:

>100_bases
AGCGCTAAAACTCTCCCTCAAATCATAAGGGAGAGTACATCTTTTATAAACCAGCTTCGTAATCGGTATTGGAGAGAAGT
TGATCTACGTCTGCGATGTT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MNALNTLIQKNTTKEITLSLPQQLKAKYSLAPIFLEQIAEHRQTIQNILAGKDSRLLVVTGPCSIHDPVSALQYAQRLVK
LQDQVKDQIFLVMRAYLEKPRTTIGWKGFLYDPNLDGSSDLQLGLEKSRALYLQIIEMGLPIASEILSPMATGYFDDLLA
WGAIGARTSESQIHREISSHMPFPIGFKNGTDGSIQIALDAIQSAQNEHQFLGMSQLGQPAILQSSGNPLPHLILRGAND
GPNYDIQSISNIRAKHKGELPALVIDCSHGNSSKDPMKQPQVLRQIIAERIESDVRGVMLESHLVDGNQKISCDITYGQS
VTDGCLGWEKTENLLLEMADQLAQCPLRQSA

Sequences:

>Translated_351_residues
MNALNTLIQKNTTKEITLSLPQQLKAKYSLAPIFLEQIAEHRQTIQNILAGKDSRLLVVTGPCSIHDPVSALQYAQRLVK
LQDQVKDQIFLVMRAYLEKPRTTIGWKGFLYDPNLDGSSDLQLGLEKSRALYLQIIEMGLPIASEILSPMATGYFDDLLA
WGAIGARTSESQIHREISSHMPFPIGFKNGTDGSIQIALDAIQSAQNEHQFLGMSQLGQPAILQSSGNPLPHLILRGAND
GPNYDIQSISNIRAKHKGELPALVIDCSHGNSSKDPMKQPQVLRQIIAERIESDVRGVMLESHLVDGNQKISCDITYGQS
VTDGCLGWEKTENLLLEMADQLAQCPLRQSA
>Mature_351_residues
MNALNTLIQKNTTKEITLSLPQQLKAKYSLAPIFLEQIAEHRQTIQNILAGKDSRLLVVTGPCSIHDPVSALQYAQRLVK
LQDQVKDQIFLVMRAYLEKPRTTIGWKGFLYDPNLDGSSDLQLGLEKSRALYLQIIEMGLPIASEILSPMATGYFDDLLA
WGAIGARTSESQIHREISSHMPFPIGFKNGTDGSIQIALDAIQSAQNEHQFLGMSQLGQPAILQSSGNPLPHLILRGAND
GPNYDIQSISNIRAKHKGELPALVIDCSHGNSSKDPMKQPQVLRQIIAERIESDVRGVMLESHLVDGNQKISCDITYGQS
VTDGCLGWEKTENLLLEMADQLAQCPLRQSA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=348, Percent_Identity=46.8390804597701, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI1786969, Length=348, Percent_Identity=45.4022988505747, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1787996, Length=342, Percent_Identity=45.0292397660819, Blast_Score=300, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6319726, Length=338, Percent_Identity=44.6745562130178, Blast_Score=307, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6320240, Length=336, Percent_Identity=43.1547619047619, Blast_Score=290, Evalue=2e-79,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38716; Mature: 38716

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALNTLIQKNTTKEITLSLPQQLKAKYSLAPIFLEQIAEHRQTIQNILAGKDSRLLVVT
CCHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GPCSIHDPVSALQYAQRLVKLQDQVKDQIFLVMRAYLEKPRTTIGWKGFLYDPNLDGSSD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCC
LQLGLEKSRALYLQIIEMGLPIASEILSPMATGYFDDLLAWGAIGARTSESQIHREISSH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
MPFPIGFKNGTDGSIQIALDAIQSAQNEHQFLGMSQLGQPAILQSSGNPLPHLILRGAND
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHCCCCEEECCCCCCCCEEEEECCCC
GPNYDIQSISNIRAKHKGELPALVIDCSHGNSSKDPMKQPQVLRQIIAERIESDVRGVML
CCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ESHLVDGNQKISCDITYGQSVTDGCLGWEKTENLLLEMADQLAQCPLRQSA
HHHCCCCCCEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNALNTLIQKNTTKEITLSLPQQLKAKYSLAPIFLEQIAEHRQTIQNILAGKDSRLLVVT
CCHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GPCSIHDPVSALQYAQRLVKLQDQVKDQIFLVMRAYLEKPRTTIGWKGFLYDPNLDGSSD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCC
LQLGLEKSRALYLQIIEMGLPIASEILSPMATGYFDDLLAWGAIGARTSESQIHREISSH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
MPFPIGFKNGTDGSIQIALDAIQSAQNEHQFLGMSQLGQPAILQSSGNPLPHLILRGAND
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCHHHCCCCEEECCCCCCCCEEEEECCCC
GPNYDIQSISNIRAKHKGELPALVIDCSHGNSSKDPMKQPQVLRQIIAERIESDVRGVML
CCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ESHLVDGNQKISCDITYGQSVTDGCLGWEKTENLLLEMADQLAQCPLRQSA
HHHCCCCCCEEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]