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The map label for this gene is hcaT [H]

Identifier: 50085014

GI number: 50085014

Start: 1864845

End: 1866008

Strand: Reverse

Name: hcaT [H]

Synonym: ACIAD1870

Alternate gene names: 50085014

Gene position: 1866008-1864845 (Counterclockwise)

Preceding gene: 50085019

Following gene: 50085007

Centisome position: 51.85

GC content: 38.23

Gene sequence:

>1164_bases
GTGTTACAGCTTCCAATTACGACTAAACTTGGCGGATTTTACTTCTTTTACTATGCCATTGTCGGAACCTTCATGCCATA
TTGGAGCCTTTATTTAGAAAATCAGGGATTCAACTATAAAGAGATTGGTTTACTTTCTTCGATTGCCATCATTACACGAT
TTTTTGCGCCATTTATATGGGGCTGGGTGGCAGATAAGACTGGCAAAAGGATGCTGCTAGTGCGTATTGCGACATGGATG
GAAGCGTGCATCTGGTTGGCAATTTTCGTAATTTCAAAGAGTTTACAATCGATTGCATTATTAATGCTGATTTTCAGTTT
TTTTCAAAATGCCATTCTTGCCCAGTTTGAAGGTGTAACATTATTTTGGTTAGCAGATAAACGCAATGAATTATATGGAA
AAGTTCGAAAATGGGGTTCTGTGGGTTTTATCACAAGTGTATTTGGTATTGGAGCTTTGTTAGAAATTATTCCCGTATCG
ATGCTGCCCATTCTACTACTATGTATTTCCTTTTTGGCCTTCATCTGGTCATTTCAAATTAAAGAACCACAACGTGCACC
CGCAGCACAACGCGCTTTAGAACCATTATTACCTATTTTAAAACGACCCATTGTATTTGGCTTTTTTATTATTGAATTTA
TTTTGTTGTTTTCCCATGCGCCATTTTATAGTTTTTATAGTAATTTTCTAAAAGAATCAGGTTTTTCAACTATCCAAATT
GGCGGTTTATGGGCGGTAGGTGTAATTGGCGAAATTATTATGTTCGCCTATGCACATATTTTGTTTAAGCGATATTCATT
ACGCACACTGGTAAGTATTTGTCTTGTTATAACCAGTCTGCGATGGTGGATTTCTGGCTATTTTGCGACTGATTTTTGGG
GACAGTTTTCGGCACAAACCATGCATTCATTCAGTTTTGGTTTATTTCATTTGATTGCAATGCGAGTAATCTTTAAAAAC
TTTTCGGCACAGCAGCAAGGACGGGGGCAGGCGTTATATAGCACCATGTGGGGCTTAGGCGTAGCATCTGGGAGTATTCT
GGCAGGGCAATTCTGGCAAATGTATACAGGCCCAGTTATTTTTATGATTGTTGCAGTTATTGTCTTAAGTGGTTTAATCT
TTGTAAGATGGCTGCCAAATAACGATGTGCAGCCATCTTCCTAA

Upstream 100 bases:

>100_bases
GCTCAACGAAAAGTTTATAAAAGTATAGGTTGCACAATTCTAATGATCTATATGAATGACAATTCTTTAATTGCTGAAAA
TTAAGCAAGGACAAATGTAA

Downstream 100 bases:

>100_bases
CGATTTACTGTAGCGGATTTTATCTTATAAATTTGTATTTTCTTCTGAGACAATCGAACTAGATAATAATTTAAAATCTG
CCCCAGAGGGTGCTTGGTAA

Product: MFS superfamily metabolite transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MLQLPITTKLGGFYFFYYAIVGTFMPYWSLYLENQGFNYKEIGLLSSIAIITRFFAPFIWGWVADKTGKRMLLVRIATWM
EACIWLAIFVISKSLQSIALLMLIFSFFQNAILAQFEGVTLFWLADKRNELYGKVRKWGSVGFITSVFGIGALLEIIPVS
MLPILLLCISFLAFIWSFQIKEPQRAPAAQRALEPLLPILKRPIVFGFFIIEFILLFSHAPFYSFYSNFLKESGFSTIQI
GGLWAVGVIGEIIMFAYAHILFKRYSLRTLVSICLVITSLRWWISGYFATDFWGQFSAQTMHSFSFGLFHLIAMRVIFKN
FSAQQQGRGQALYSTMWGLGVASGSILAGQFWQMYTGPVIFMIVAVIVLSGLIFVRWLPNNDVQPSS

Sequences:

>Translated_387_residues
MLQLPITTKLGGFYFFYYAIVGTFMPYWSLYLENQGFNYKEIGLLSSIAIITRFFAPFIWGWVADKTGKRMLLVRIATWM
EACIWLAIFVISKSLQSIALLMLIFSFFQNAILAQFEGVTLFWLADKRNELYGKVRKWGSVGFITSVFGIGALLEIIPVS
MLPILLLCISFLAFIWSFQIKEPQRAPAAQRALEPLLPILKRPIVFGFFIIEFILLFSHAPFYSFYSNFLKESGFSTIQI
GGLWAVGVIGEIIMFAYAHILFKRYSLRTLVSICLVITSLRWWISGYFATDFWGQFSAQTMHSFSFGLFHLIAMRVIFKN
FSAQQQGRGQALYSTMWGLGVASGSILAGQFWQMYTGPVIFMIVAVIVLSGLIFVRWLPNNDVQPSS
>Mature_387_residues
MLQLPITTKLGGFYFFYYAIVGTFMPYWSLYLENQGFNYKEIGLLSSIAIITRFFAPFIWGWVADKTGKRMLLVRIATWM
EACIWLAIFVISKSLQSIALLMLIFSFFQNAILAQFEGVTLFWLADKRNELYGKVRKWGSVGFITSVFGIGALLEIIPVS
MLPILLLCISFLAFIWSFQIKEPQRAPAAQRALEPLLPILKRPIVFGFFIIEFILLFSHAPFYSFYSNFLKESGFSTIQI
GGLWAVGVIGEIIMFAYAHILFKRYSLRTLVSICLVITSLRWWISGYFATDFWGQFSAQTMHSFSFGLFHLIAMRVIFKN
FSAQQQGRGQALYSTMWGLGVASGSILAGQFWQMYTGPVIFMIVAVIVLSGLIFVRWLPNNDVQPSS

Specific function: Probable permease involved in the uptake of 3- phenylpropionic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacY/rafB permease family. HcaT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788886, Length=372, Percent_Identity=27.4193548387097, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022814
- InterPro:   IPR016196
- InterPro:   IPR005276 [H]

Pfam domain/function: PF01306 LacY_symp [H]

EC number: NA

Molecular weight: Translated: 44116; Mature: 44116

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLPITTKLGGFYFFYYAIVGTFMPYWSLYLENQGFNYKEIGLLSSIAIITRFFAPFIW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GWVADKTGKRMLLVRIATWMEACIWLAIFVISKSLQSIALLMLIFSFFQNAILAQFEGVT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LFWLADKRNELYGKVRKWGSVGFITSVFGIGALLEIIPVSMLPILLLCISFLAFIWSFQI
EEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KEPQRAPAAQRALEPLLPILKRPIVFGFFIIEFILLFSHAPFYSFYSNFLKESGFSTIQI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEE
GGLWAVGVIGEIIMFAYAHILFKRYSLRTLVSICLVITSLRWWISGYFATDFWGQFSAQT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHSFSFGLFHLIAMRVIFKNFSAQQQGRGQALYSTMWGLGVASGSILAGQFWQMYTGPVI
HHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FMIVAVIVLSGLIFVRWLPNNDVQPSS
HHHHHHHHHHHHHHEEECCCCCCCCCC
>Mature Secondary Structure
MLQLPITTKLGGFYFFYYAIVGTFMPYWSLYLENQGFNYKEIGLLSSIAIITRFFAPFIW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GWVADKTGKRMLLVRIATWMEACIWLAIFVISKSLQSIALLMLIFSFFQNAILAQFEGVT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
LFWLADKRNELYGKVRKWGSVGFITSVFGIGALLEIIPVSMLPILLLCISFLAFIWSFQI
EEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KEPQRAPAAQRALEPLLPILKRPIVFGFFIIEFILLFSHAPFYSFYSNFLKESGFSTIQI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEE
GGLWAVGVIGEIIMFAYAHILFKRYSLRTLVSICLVITSLRWWISGYFATDFWGQFSAQT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MHSFSFGLFHLIAMRVIFKNFSAQQQGRGQALYSTMWGLGVASGSILAGQFWQMYTGPVI
HHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
FMIVAVIVLSGLIFVRWLPNNDVQPSS
HHHHHHHHHHHHHHEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9603882; 9205837; 9278503 [H]