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The map label for this gene is gstB [H]

Identifier: 50084488

GI number: 50084488

Start: 1308423

End: 1309034

Strand: Direct

Name: gstB [H]

Synonym: ACIAD1305

Alternate gene names: 50084488

Gene position: 1308423-1309034 (Clockwise)

Preceding gene: 50084486

Following gene: 50084495

Centisome position: 36.36

GC content: 39.87

Gene sequence:

>612_bases
ATGAAGTTGTATTACTCACCAGGCGCATGTTCATTGGCAGCACATATCATTCTCAATGAAATTAATGTCGATTTTGATCT
AGAAAAAGTTGATCTTAAAACACATAAAACAGAAAAAGGCGCAGATTACTATGAAGTCAATCCGAAAGGCTATGTACCAG
CACTTGAAATTAATCCAGGGTTGATCCTCACTGAAAATGTTGCGATTCTGCCTTTTCTGGCACAGCATGATCCAAAACAG
GATTTGATTCCACCATCGGGCATGGGGCGTGCCAAAGTTTTAGAATGGTTGGGATATCTTAATTCTGAGTTGCATGATGC
TTATGCTGTTTTCTTTGGTGCGCCGTTAGAAGGTGAAGCAAAAGAAAAAGCCTATAAAGAAGTAGACCGCTTGCTGAACT
ATATCAATCGGGCGATTGGTGAGTCTGAAAATGAATATCTTGTAGACGATAATTTTGGTCCAGCAGATGCTTATCTGTTT
GTGCTTACCAATTGGTCAAAAAGTATTGGGCATGATTTGAGTCCTTATCAAAATATCAATGCGATCCGTGATAAGGTTGC
AGCACGTCAATCTGTCCAAATTGCAATGCGCGATGAAGGCTTGATTGCATAA

Upstream 100 bases:

>100_bases
GATTATCTTGGCTTTACTTTTGTAAGGAAGTTTATATAACCCTTGCATGTTACCTAGAAGCGTTTTAGAACATAAAATAG
TTTGATAACAAGGATCCAAT

Downstream 100 bases:

>100_bases
CTTCACGCAGAAAAAATGCCTCAAGTAATTGAGGTATTTTTCTATTCAAATTCTGGTGGTTCTTTAAAATTGATAGATTG
CAATTTTAAATCATATTGTT

Product: glutathionine S-transferase

Products: NA

Alternate protein names: GST B1-1 [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKLYYSPGACSLAAHIILNEINVDFDLEKVDLKTHKTEKGADYYEVNPKGYVPALEINPGLILTENVAILPFLAQHDPKQ
DLIPPSGMGRAKVLEWLGYLNSELHDAYAVFFGAPLEGEAKEKAYKEVDRLLNYINRAIGESENEYLVDDNFGPADAYLF
VLTNWSKSIGHDLSPYQNINAIRDKVAARQSVQIAMRDEGLIA

Sequences:

>Translated_203_residues
MKLYYSPGACSLAAHIILNEINVDFDLEKVDLKTHKTEKGADYYEVNPKGYVPALEINPGLILTENVAILPFLAQHDPKQ
DLIPPSGMGRAKVLEWLGYLNSELHDAYAVFFGAPLEGEAKEKAYKEVDRLLNYINRAIGESENEYLVDDNFGPADAYLF
VLTNWSKSIGHDLSPYQNINAIRDKVAARQSVQIAMRDEGLIA
>Mature_203_residues
MKLYYSPGACSLAAHIILNEINVDFDLEKVDLKTHKTEKGADYYEVNPKGYVPALEINPGLILTENVAILPFLAQHDPKQ
DLIPPSGMGRAKVLEWLGYLNSELHDAYAVFFGAPLEGEAKEKAYKEVDRLLNYINRAIGESENEYLVDDNFGPADAYLF
VLTNWSKSIGHDLSPYQNINAIRDKVAARQSVQIAMRDEGLIA

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=202, Percent_Identity=40.5940594059406, Blast_Score=143, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24645375, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553325, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355859, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22686; Mature: 22686

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYYSPGACSLAAHIILNEINVDFDLEKVDLKTHKTEKGADYYEVNPKGYVPALEINPG
CEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCEEEEECCC
LILTENVAILPFLAQHDPKQDLIPPSGMGRAKVLEWLGYLNSELHDAYAVFFGAPLEGEA
EEEECCCEEEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCH
KEKAYKEVDRLLNYINRAIGESENEYLVDDNFGPADAYLFVLTNWSKSIGHDLSPYQNIN
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCHHHCCCCCCHHHHH
AIRDKVAARQSVQIAMRDEGLIA
HHHHHHHHHHHEEEEECCCCCCC
>Mature Secondary Structure
MKLYYSPGACSLAAHIILNEINVDFDLEKVDLKTHKTEKGADYYEVNPKGYVPALEINPG
CEEEECCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCEEEEECCC
LILTENVAILPFLAQHDPKQDLIPPSGMGRAKVLEWLGYLNSELHDAYAVFFGAPLEGEA
EEEECCCEEEEHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCH
KEKAYKEVDRLLNYINRAIGESENEYLVDDNFGPADAYLFVLTNWSKSIGHDLSPYQNIN
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEEECCCHHHCCCCCCHHHHH
AIRDKVAARQSVQIAMRDEGLIA
HHHHHHHHHHHEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8761466; 8436105; 2661269; 8645008; 9655824 [H]