Click here to switch to the map view.

The map label for this gene is glsA [H]

Identifier: 50084242

GI number: 50084242

Start: 1030547

End: 1031812

Strand: Direct

Name: glsA [H]

Synonym: ACIAD1040

Alternate gene names: 50084242

Gene position: 1030547-1031812 (Clockwise)

Preceding gene: 50084241

Following gene: 50084244

Centisome position: 28.64

GC content: 42.73

Gene sequence:

>1266_bases
ATGCAAACGCCCGTTCCTGAATATCTGGCTCATGTCATTGATCAGTGTGAAAACAATCAGACGGGTAAACTAGCCGATTA
TATTCCTGAGCTTGCCCATGCCAATCCCGACCAAGTCGCGCTGGCCATGTCAACGGTTGATGGGCAAATTTATGCGGTTG
GTGATGAGGATATTGAATTTACCATTCAATCGATGTCAAAGCCATTTACTTACGCATATGTGTTGCAACAGCTAGGGCTG
GATGAAGTTCTTGATAAGGTGGGTGTTGAACCTTCTGGGGAAGCTTTCAATGAAATTTCTTTAGGTCATGATAAACGCCC
TAAAAATCCCATGATTAACTCTGGTGCGATAACCACGCACTCACTTATTCCTATTAAAGATCAGCTTGAAAGTGCTGAAA
TAATACGTCGTTTTATGAGTGAGCTCGCAGGACGTGAGTTATGTTTCGATGAAGCGGTATATGCCTCTGAAATCAAAACA
GCATACCGTAATCTTTCTATCGGCTATATGCTCAGAACCGTTGGAATTTTGGAAACCGATCCTGTAGATATCGTCAATGG
ATATATACGTCAGTGCTCAATTCTAGTGACTGTTAAAGATTTGGTAAAAATGGGCAGTATTCTAGCCAATGGTGGTATTG
ATGCCACCACAGGTAAACGACTATTGAACCGTGATGTGGTACGTCAAGTTTTAAGTGTCATGATGAGTTGTGGTATGTAT
GATGCCGCTGGCGATTGGCTTACCACTGTGGGTATTCCTGCCAAAAGTGGTGTCGCAGGTGGGATTTTAGGCGTGTTGCC
AGGGCAGGTCAGTATTGCCGCGTTTTCACCTCGACTCGATGAACATGGTAATAGTGTACGCGGGATCGAGATGATGGAGC
GCTTGTCTCGAGATATGGGATTACATTTGATGGAAGGAACGCCTTCTGCACAAACTATTGTACAAAGTCATTATCGGACA
GGAAAAAATGCCTCGACTAGTATTTATGTACTCCGTGGGGTTTTAAAATTTACCGAAGCAGAAATGTTATTACGTATATT
TCAGGGTGAAGCAGTGGATGAAAGTACAATCGTCATTGACTTAACCCAGATTTCATTGATTCATGATGTGGGTAAACGTA
TGTTTTTAGAAGGTGTTGATCGTTTGATTGATGATGGTCATAGCGTGCTTCTCGTTGATCCTGAGCAACGGCTAGAACAG
GCGCGTACTCACAAAGATCGAGTACTACATGTGTATCAGAATATGGATGAACTGTTAGAAAAATAG

Upstream 100 bases:

>100_bases
TAAAACAAATCGCTATATTACAAAAGACCTGATTTTAGTATTATAAATTCGCTGTACCATCAAAATTAAAATAAACTCGA
AAAATTGAAGGTTTAGCCTT

Downstream 100 bases:

>100_bases
TCTGACCTATGTTGATCGTATAGTCAGGTACAGATTATTTTTTATATTGCTTAAACTGCTGAGGAGTAATGCCCATATGA
CGTTTAAACATCGCACTAAA

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MQTPVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGL
DEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLIPIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKT
AYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMY
DAAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHLMEGTPSAQTIVQSHYRT
GKNASTSIYVLRGVLKFTEAEMLLRIFQGEAVDESTIVIDLTQISLIHDVGKRMFLEGVDRLIDDGHSVLLVDPEQRLEQ
ARTHKDRVLHVYQNMDELLEK

Sequences:

>Translated_421_residues
MQTPVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGL
DEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLIPIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKT
AYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMY
DAAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHLMEGTPSAQTIVQSHYRT
GKNASTSIYVLRGVLKFTEAEMLLRIFQGEAVDESTIVIDLTQISLIHDVGKRMFLEGVDRLIDDGHSVLLVDPEQRLEQ
ARTHKDRVLHVYQNMDELLEK
>Mature_421_residues
MQTPVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEFTIQSMSKPFTYAYVLQQLGL
DEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTHSLIPIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKT
AYRNLSIGYMLRTVGILETDPVDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMY
DAAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMGLHLMEGTPSAQTIVQSHYRT
GKNASTSIYVLRGVLKFTEAEMLLRIFQGEAVDESTIVIDLTQISLIHDVGKRMFLEGVDRLIDDGHSVLLVDPEQRLEQ
ARTHKDRVLHVYQNMDELLEK

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=308, Percent_Identity=40.2597402597403, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI20336214, Length=285, Percent_Identity=41.0526315789474, Blast_Score=216, Evalue=2e-56,
Organism=Escherichia coli, GI1786693, Length=287, Percent_Identity=41.1149825783972, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1787804, Length=287, Percent_Identity=32.7526132404181, Blast_Score=174, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17507019, Length=301, Percent_Identity=39.8671096345515, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17532727, Length=309, Percent_Identity=39.4822006472492, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI193204073, Length=347, Percent_Identity=33.1412103746398, Blast_Score=198, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI193204075, Length=349, Percent_Identity=33.2378223495702, Blast_Score=198, Evalue=6e-51,
Organism=Drosophila melanogaster, GI281363239, Length=312, Percent_Identity=41.9871794871795, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI281363241, Length=315, Percent_Identity=41.9047619047619, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24653164, Length=312, Percent_Identity=41.9871794871795, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24653156, Length=312, Percent_Identity=41.9871794871795, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24653158, Length=312, Percent_Identity=41.9871794871795, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI24653162, Length=315, Percent_Identity=41.9047619047619, Blast_Score=249, Evalue=3e-66,
Organism=Drosophila melanogaster, GI116008307, Length=315, Percent_Identity=41.9047619047619, Blast_Score=248, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24653166, Length=312, Percent_Identity=41.9871794871795, Blast_Score=248, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868
- InterPro:   IPR002645 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 46408; Mature: 46408

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTPVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEF
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCHHH
TIQSMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTH
HHHHCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEC
SLIPIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETD
EECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
PVDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMY
CHHHHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
DAAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMG
CCCCCCCEECCCCCCCCCCCCHHHHCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHCC
LHLMEGTPSAQTIVQSHYRTGKNASTSIYVLRGVLKFTEAEMLLRIFQGEAVDESTIVID
CEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LTQISLIHDVGKRMFLEGVDRLIDDGHSVLLVDPEQRLEQARTHKDRVLHVYQNMDELLE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHC
K
C
>Mature Secondary Structure
MQTPVPEYLAHVIDQCENNQTGKLADYIPELAHANPDQVALAMSTVDGQIYAVGDEDIEF
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCEEEEECCCCHHH
TIQSMSKPFTYAYVLQQLGLDEVLDKVGVEPSGEAFNEISLGHDKRPKNPMINSGAITTH
HHHHCCCCHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCEEC
SLIPIKDQLESAEIIRRFMSELAGRELCFDEAVYASEIKTAYRNLSIGYMLRTVGILETD
EECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
PVDIVNGYIRQCSILVTVKDLVKMGSILANGGIDATTGKRLLNRDVVRQVLSVMMSCGMY
CHHHHHHHHHHHHHHEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
DAAGDWLTTVGIPAKSGVAGGILGVLPGQVSIAAFSPRLDEHGNSVRGIEMMERLSRDMG
CCCCCCCEECCCCCCCCCCCCHHHHCCCCEEEEEECCCHHHCCCCCHHHHHHHHHHHHCC
LHLMEGTPSAQTIVQSHYRTGKNASTSIYVLRGVLKFTEAEMLLRIFQGEAVDESTIVID
CEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
LTQISLIHDVGKRMFLEGVDRLIDDGHSVLLVDPEQRLEQARTHKDRVLHVYQNMDELLE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12948626 [H]