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The map label for this gene is katA [H]

Identifier: 50083700

GI number: 50083700

Start: 447419

End: 448939

Strand: Reverse

Name: katA [H]

Synonym: ACIAD0451

Alternate gene names: 50083700

Gene position: 448939-447419 (Counterclockwise)

Preceding gene: 50083702

Following gene: 50083697

Centisome position: 12.48

GC content: 45.63

Gene sequence:

>1521_bases
ATGAGTGACGATAAGTTAAAGTGTCCAGTCACCCACCTTACGACTGATGCAGGCGCGCCTGTTGTAGACAATCAGAACAG
TATGACGGCAGGTGCACGTGGTCCACTTCTGACCCAAGATCTCTGGCTCAATGAGAAAATGGCTAATTTTGCACGTGAAG
TTATTCCAGAACGTCGTATGCATGCCAAAGGGTCAGGAGCATTTGGTACTTTTACGGTAACCCACGATATTACACAGTAT
TCCCGTGCCAAAATATTCAGTGAAATTGGGAAAAAAACTGAAATGTTTGCCCGCTTTTCAACGGTCGCAGGTGAACGTGG
TGCTGCCGATGCAGAACGTGATATTCGCGGTTTTGCCCTCAAGTTTTATACCGAAGAAGGTAACTGGGACATGGTGGGAA
ACAATACGCCTGTGTTCTTTATGCGTGATCCACGTAAGTTCCCAGATCTTAACAAAGCAGTAAAACGCGACCCAAAAACT
AATTTACGTAGTGCCACCTATAACTGGGATTTCTGGACGCTACTGCCTGAAGCACTGCATCAGGTCACAATTGTGATGTC
AGATCGTGGTATTCCAGATGGATATCGCCATATGCATGGTTTTGGTAGCCATACTTATAGCTTCATCAATGCCAGCAATG
AGCGCTTTTGGGTAAAATTCCATTTCCGCACCCAGCAAGGTATTAAGAATTTAACTGATGCTGAAGCTGAAGCGATTGTT
GCCAAAGACCGTGAAAGTAGCCAAAGCGATTTGTTCAATGCGATTGAACAAGGTAACTATCCAAAATGGACCATGTTCGT
TCAAATCATGCCAGAAACTGATGCGGAAAAAGTACCCTATCATCCATTTGACCTCACTAAAGTCTGGCCGCATGGGGATT
ACCCACTGATCGAAGTCGGTGAATTTGAACTAAATCGTAATGCTGAAAATTATTTTCAGGATGTTGAGCAAGCGACATTT
GCACCAAGTAATCTAGTTCCAGGGATTAGCTACTCTCCAGACCGCATGTTACAAGCACGTTTGGTGAACTATGCCGATGC
ACACCGCTATCGTGTTGGTGTAAATCACACTCAAATTCCAGTAAATGCGCCGCGTTGTCCAGTGCATAGTAACCGCCGTG
ACGGACAAGGCCGTATGGATGGTAACTATGGTGGTTTACCACACTACGAACCGAACAGTTTCCATCAATGGCAAGAACAG
CCTGAGTTTCGTGAACCGCCTTTAAAAATTACGGGCGATGCAGATTTCTGGGATTTCCGTCAAGATGACAGCGACTATTT
TAGCCAGCCCCGTGCTTTGTTTAATTTGATGAATGATGAGCAAAAACAGGCATTATTTGGTAATACGGCACGTGCGATGG
GTGATGCGCTCGACTTCATTAAATATCGCCACATCCGTAATTGCTACGCCTGTGATCCTGCCTATGGAGAAGGTGTTGCT
CAGGCACTCGGCATGACGGTTGCAGATGCTCAAGCAGCCCGTGACAGTGATCCTGCTAAAGGTCATCCTGGTTTCTTATA
A

Upstream 100 bases:

>100_bases
TGCAATGTTATTCGAGGATAGGAATGCTAGTTATATAATGTTGCTATATCCATGACATTATTAAAATTTTCACTACTAAA
ACACTTGACGGAGAATTCTA

Downstream 100 bases:

>100_bases
TAGAAAAGCAATAAAAAACCACCTGCGGGTGGTTTTTTATTGCAAACAAAAAGCTTTAAACAGTGAGCTTATGTCCTTCA
CGGATACAGTAAAATGGATT

Product: catalase (hydroperoxidase II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSDDKLKCPVTHLTTDAGAPVVDNQNSMTAGARGPLLTQDLWLNEKMANFAREVIPERRMHAKGSGAFGTFTVTHDITQY
SRAKIFSEIGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDMVGNNTPVFFMRDPRKFPDLNKAVKRDPKT
NLRSATYNWDFWTLLPEALHQVTIVMSDRGIPDGYRHMHGFGSHTYSFINASNERFWVKFHFRTQQGIKNLTDAEAEAIV
AKDRESSQSDLFNAIEQGNYPKWTMFVQIMPETDAEKVPYHPFDLTKVWPHGDYPLIEVGEFELNRNAENYFQDVEQATF
APSNLVPGISYSPDRMLQARLVNYADAHRYRVGVNHTQIPVNAPRCPVHSNRRDGQGRMDGNYGGLPHYEPNSFHQWQEQ
PEFREPPLKITGDADFWDFRQDDSDYFSQPRALFNLMNDEQKQALFGNTARAMGDALDFIKYRHIRNCYACDPAYGEGVA
QALGMTVADAQAARDSDPAKGHPGFL

Sequences:

>Translated_506_residues
MSDDKLKCPVTHLTTDAGAPVVDNQNSMTAGARGPLLTQDLWLNEKMANFAREVIPERRMHAKGSGAFGTFTVTHDITQY
SRAKIFSEIGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDMVGNNTPVFFMRDPRKFPDLNKAVKRDPKT
NLRSATYNWDFWTLLPEALHQVTIVMSDRGIPDGYRHMHGFGSHTYSFINASNERFWVKFHFRTQQGIKNLTDAEAEAIV
AKDRESSQSDLFNAIEQGNYPKWTMFVQIMPETDAEKVPYHPFDLTKVWPHGDYPLIEVGEFELNRNAENYFQDVEQATF
APSNLVPGISYSPDRMLQARLVNYADAHRYRVGVNHTQIPVNAPRCPVHSNRRDGQGRMDGNYGGLPHYEPNSFHQWQEQ
PEFREPPLKITGDADFWDFRQDDSDYFSQPRALFNLMNDEQKQALFGNTARAMGDALDFIKYRHIRNCYACDPAYGEGVA
QALGMTVADAQAARDSDPAKGHPGFL
>Mature_505_residues
SDDKLKCPVTHLTTDAGAPVVDNQNSMTAGARGPLLTQDLWLNEKMANFAREVIPERRMHAKGSGAFGTFTVTHDITQYS
RAKIFSEIGKKTEMFARFSTVAGERGAADAERDIRGFALKFYTEEGNWDMVGNNTPVFFMRDPRKFPDLNKAVKRDPKTN
LRSATYNWDFWTLLPEALHQVTIVMSDRGIPDGYRHMHGFGSHTYSFINASNERFWVKFHFRTQQGIKNLTDAEAEAIVA
KDRESSQSDLFNAIEQGNYPKWTMFVQIMPETDAEKVPYHPFDLTKVWPHGDYPLIEVGEFELNRNAENYFQDVEQATFA
PSNLVPGISYSPDRMLQARLVNYADAHRYRVGVNHTQIPVNAPRCPVHSNRRDGQGRMDGNYGGLPHYEPNSFHQWQEQP
EFREPPLKITGDADFWDFRQDDSDYFSQPRALFNLMNDEQKQALFGNTARAMGDALDFIKYRHIRNCYACDPAYGEGVAQ
ALGMTVADAQAARDSDPAKGHPGFL

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=473, Percent_Identity=52.8541226215645, Blast_Score=504, Evalue=1e-143,
Organism=Escherichia coli, GI48994891, Length=497, Percent_Identity=39.2354124748491, Blast_Score=334, Evalue=8e-93,
Organism=Caenorhabditis elegans, GI71998444, Length=473, Percent_Identity=48.6257928118393, Blast_Score=470, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI25151141, Length=473, Percent_Identity=47.9915433403806, Blast_Score=468, Evalue=1e-132,
Organism=Caenorhabditis elegans, GI25147792, Length=473, Percent_Identity=47.7801268498943, Blast_Score=467, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6320462, Length=385, Percent_Identity=52.4675324675325, Blast_Score=386, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6321525, Length=512, Percent_Identity=34.5703125, Blast_Score=289, Evalue=7e-79,
Organism=Drosophila melanogaster, GI17981717, Length=477, Percent_Identity=47.1698113207547, Blast_Score=446, Evalue=1e-125,
Organism=Drosophila melanogaster, GI19920968, Length=474, Percent_Identity=44.0928270042194, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 57552; Mature: 57421

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDKLKCPVTHLTTDAGAPVVDNQNSMTAGARGPLLTQDLWLNEKMANFAREVIPERRM
CCCCCEECCHHEEECCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HAKGSGAFGTFTVTHDITQYSRAKIFSEIGKKTEMFARFSTVAGERGAADAERDIRGFAL
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHCCCEEEE
KFYTEEGNWDMVGNNTPVFFMRDPRKFPDLNKAVKRDPKTNLRSATYNWDFWTLLPEALH
EEEEECCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
QVTIVMSDRGIPDGYRHMHGFGSHTYSFINASNERFWVKFHFRTQQGIKNLTDAEAEAIV
HEEEEEECCCCCHHHHHHHCCCCCEEEEEECCCCEEEEEEEEECHHHHHHHHHHHHHHEE
AKDRESSQSDLFNAIEQGNYPKWTMFVQIMPETDAEKVPYHPFDLTKVWPHGDYPLIEVG
ECCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCEEEEC
EFELNRNAENYFQDVEQATFAPSNLVPGISYSPDRMLQARLVNYADAHRYRVGVNHTQIP
CEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEECC
VNAPRCPVHSNRRDGQGRMDGNYGGLPHYEPNSFHQWQEQPEFREPPLKITGDADFWDFR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCC
QDDSDYFSQPRALFNLMNDEQKQALFGNTARAMGDALDFIKYRHIRNCYACDPAYGEGVA
CCCHHHHHCHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
QALGMTVADAQAARDSDPAKGHPGFL
HHHCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SDDKLKCPVTHLTTDAGAPVVDNQNSMTAGARGPLLTQDLWLNEKMANFAREVIPERRM
CCCCEECCHHEEECCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HAKGSGAFGTFTVTHDITQYSRAKIFSEIGKKTEMFARFSTVAGERGAADAERDIRGFAL
CCCCCCCEEEEEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHCCCEEEE
KFYTEEGNWDMVGNNTPVFFMRDPRKFPDLNKAVKRDPKTNLRSATYNWDFWTLLPEALH
EEEEECCCEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCCCCCEECCCHHHHHHHHHHH
QVTIVMSDRGIPDGYRHMHGFGSHTYSFINASNERFWVKFHFRTQQGIKNLTDAEAEAIV
HEEEEEECCCCCHHHHHHHCCCCCEEEEEECCCCEEEEEEEEECHHHHHHHHHHHHHHEE
AKDRESSQSDLFNAIEQGNYPKWTMFVQIMPETDAEKVPYHPFDLTKVWPHGDYPLIEVG
ECCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCEEEEC
EFELNRNAENYFQDVEQATFAPSNLVPGISYSPDRMLQARLVNYADAHRYRVGVNHTQIP
CEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEECC
VNAPRCPVHSNRRDGQGRMDGNYGGLPHYEPNSFHQWQEQPEFREPPLKITGDADFWDFR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCC
QDDSDYFSQPRALFNLMNDEQKQALFGNTARAMGDALDFIKYRHIRNCYACDPAYGEGVA
CCCHHHHHCHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
QALGMTVADAQAARDSDPAKGHPGFL
HHHCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8188593; 7542800 [H]