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The map label for this gene is ribD [H]

Identifier: 50083525

GI number: 50083525

Start: 246659

End: 247747

Strand: Direct

Name: ribD [H]

Synonym: ACIAD0247

Alternate gene names: 50083525

Gene position: 246659-247747 (Clockwise)

Preceding gene: 50083524

Following gene: 50083526

Centisome position: 6.85

GC content: 46.19

Gene sequence:

>1089_bases
ATGTCTGAACAAGAGCGTGATCATTACTGGATGTCACAGGCACTCGCACTGGCAAAAACTGCACAATTTCGCACACGTCC
TAATCCTGCGGTTGGCTGTGTGATTGTAAAAGATCAACATATTGTTGGGCGTGGCTCGACAGCACCAGTGGGTGGCCCGC
ATGCTGAAGTGTTTGCTTTGCGTGAAGCGGGAGTTCAAGCACAGAATGCAACAGCCTATGTAACGTTAGAGCCCTGCTCA
CATTATGGACGAACACCACCATGTGCCAATGCCTTAATTGAAGCTGGAGTTTCGCGTGTCGTCATTGCAACGCTTGATCC
AAACCCGTTAGTGGCAGGAAAAGGTCAAACCATGCTCAACCAAGCGGGTATTACCACGCAAGTGGGTGTGCTTGAAGAGC
AGGCGCAAGAATTAAATCGTGGTTTCTTAAAAGTGATGGCAGGCGGATTGCCTTACGTCCGGTTAAAAGTCGCATCTAGT
CTAGATGGTCGAACTGCAATGGCATCTGGAGAATCCAAGTGGATTACTGGTGTAGATGCAAGGCTCGATGTGCAATACTG
GCGAGCACGTTCTGGCGCAATCATTACAGGTGTTGATACTGTACTGGCTGATGATTGCCAGTTAAATGTACGGGCTTTGC
CAGATGTTGATGATTTGAGTGAGATTGTACAACCGAAGCGAATTATTTTAGATCGACAAGGTCGTTTACCGCTCACAGCA
AAGCTGTTACAACATCCTGAAACTGTGGTGGTGATGGGACCATTTCGTCAGGAACTTGCTGATCTAGGTGTGGTACAATT
TCCCGTTCTGCCATTGCAACAGCTTTTAGAGCACATTGCCAAAGAGCATCATATATATGATGTCATGATTGAGGCAGGCG
CGACTTTATCTACTGCCTTTTTACAAGAAGATTTGGTTGATGAAGTCATTAGTTATGTGGCGCCAACATTATTAGGGTGT
TCTGCGCGTGCCATGTTTAATGCTGAGCTAGATAAGATGGCTCAACAATTACGATTTGAACTGATTGACCTGACTCAGCT
TGGTCAAGATATCCGTTTAAGGTTAGTTCCGATTCAAGAGACAGTATGA

Upstream 100 bases:

>100_bases
GTTCGCTTTGCCTCTGTTTATCAAGATTTTCAGGATGTCGAAGCATTTCGCCGTCAGATCGAACAAATGCAGCAACGTGA
ACAGGAATGTGAGAAACATG

Downstream 100 bases:

>100_bases
ATTCAGAGGCTTCGGTTTATCATAAACGCCGCCATGCGGCACGAACGACAGATGAATATTTGTTTCATCAACTTGTGCCT
TATCTGGGCAATAAGCGTCG

Product: bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSEQERDHYWMSQALALAKTAQFRTRPNPAVGCVIVKDQHIVGRGSTAPVGGPHAEVFALREAGVQAQNATAYVTLEPCS
HYGRTPPCANALIEAGVSRVVIATLDPNPLVAGKGQTMLNQAGITTQVGVLEEQAQELNRGFLKVMAGGLPYVRLKVASS
LDGRTAMASGESKWITGVDARLDVQYWRARSGAIITGVDTVLADDCQLNVRALPDVDDLSEIVQPKRIILDRQGRLPLTA
KLLQHPETVVVMGPFRQELADLGVVQFPVLPLQQLLEHIAKEHHIYDVMIEAGATLSTAFLQEDLVDEVISYVAPTLLGC
SARAMFNAELDKMAQQLRFELIDLTQLGQDIRLRLVPIQETV

Sequences:

>Translated_362_residues
MSEQERDHYWMSQALALAKTAQFRTRPNPAVGCVIVKDQHIVGRGSTAPVGGPHAEVFALREAGVQAQNATAYVTLEPCS
HYGRTPPCANALIEAGVSRVVIATLDPNPLVAGKGQTMLNQAGITTQVGVLEEQAQELNRGFLKVMAGGLPYVRLKVASS
LDGRTAMASGESKWITGVDARLDVQYWRARSGAIITGVDTVLADDCQLNVRALPDVDDLSEIVQPKRIILDRQGRLPLTA
KLLQHPETVVVMGPFRQELADLGVVQFPVLPLQQLLEHIAKEHHIYDVMIEAGATLSTAFLQEDLVDEVISYVAPTLLGC
SARAMFNAELDKMAQQLRFELIDLTQLGQDIRLRLVPIQETV
>Mature_361_residues
SEQERDHYWMSQALALAKTAQFRTRPNPAVGCVIVKDQHIVGRGSTAPVGGPHAEVFALREAGVQAQNATAYVTLEPCSH
YGRTPPCANALIEAGVSRVVIATLDPNPLVAGKGQTMLNQAGITTQVGVLEEQAQELNRGFLKVMAGGLPYVRLKVASSL
DGRTAMASGESKWITGVDARLDVQYWRARSGAIITGVDTVLADDCQLNVRALPDVDDLSEIVQPKRIILDRQGRLPLTAK
LLQHPETVVVMGPFRQELADLGVVQFPVLPLQQLLEHIAKEHHIYDVMIEAGATLSTAFLQEDLVDEVISYVAPTLLGCS
ARAMFNAELDKMAQQLRFELIDLTQLGQDIRLRLVPIQETV

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=366, Percent_Identity=46.7213114754098, Blast_Score=301, Evalue=6e-83,
Organism=Escherichia coli, GI145693172, Length=159, Percent_Identity=37.1069182389937, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39467; Mature: 39336

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQERDHYWMSQALALAKTAQFRTRPNPAVGCVIVKDQHIVGRGSTAPVGGPHAEVFAL
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEECCCCCCCCCCCCHHHEEE
REAGVQAQNATAYVTLEPCSHYGRTPPCANALIEAGVSRVVIATLDPNPLVAGKGQTMLN
HHCCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCEEECCCCHHHH
QAGITTQVGVLEEQAQELNRGFLKVMAGGLPYVRLKVASSLDGRTAMASGESKWITGVDA
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCCCCCEEECCCC
RLDVQYWRARSGAIITGVDTVLADDCQLNVRALPDVDDLSEIVQPKRIILDRQGRLPLTA
EEEHHHHHCCCCEEEEEHHHHHHCCCEEEEEECCCHHHHHHHHCCHHEEECCCCCCCHHH
KLLQHPETVVVMGPFRQELADLGVVQFPVLPLQQLLEHIAKEHHIYDVMIEAGATLSTAF
HHHCCCCEEEEECCHHHHHHHCCCHHCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHH
LQEDLVDEVISYVAPTLLGCSARAMFNAELDKMAQQLRFELIDLTQLGQDIRLRLVPIQE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
TV
CC
>Mature Secondary Structure 
SEQERDHYWMSQALALAKTAQFRTRPNPAVGCVIVKDQHIVGRGSTAPVGGPHAEVFAL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEECCCCCCCCCCCCHHHEEE
REAGVQAQNATAYVTLEPCSHYGRTPPCANALIEAGVSRVVIATLDPNPLVAGKGQTMLN
HHCCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHCCCCEEEEEEECCCCEEECCCCHHHH
QAGITTQVGVLEEQAQELNRGFLKVMAGGLPYVRLKVASSLDGRTAMASGESKWITGVDA
HCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECCCCCCEEECCCC
RLDVQYWRARSGAIITGVDTVLADDCQLNVRALPDVDDLSEIVQPKRIILDRQGRLPLTA
EEEHHHHHCCCCEEEEEHHHHHHCCCEEEEEECCCHHHHHHHHCCHHEEECCCCCCCHHH
KLLQHPETVVVMGPFRQELADLGVVQFPVLPLQQLLEHIAKEHHIYDVMIEAGATLSTAF
HHHCCCCEEEEECCHHHHHHHCCCHHCCHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHH
LQEDLVDEVISYVAPTLLGCSARAMFNAELDKMAQQLRFELIDLTQLGQDIRLRLVPIQE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
TV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]