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The map label for this gene is nrdR

Identifier: 50083524

GI number: 50083524

Start: 246187

End: 246666

Strand: Direct

Name: nrdR

Synonym: ACIAD0246

Alternate gene names: 50083524

Gene position: 246187-246666 (Clockwise)

Preceding gene: 50083523

Following gene: 50083525

Centisome position: 6.84

GC content: 45.42

Gene sequence:

>480_bases
ATGCATTGTCCTTTTTGCAACGCCGCAGACAGTAAGGTGATTGATTCGCGTCTGGCTGCTGAAGGGTGTCAGATCCGTCG
TCGACGCGAATGCATCAGTTGCGGTGAGCGTTTTACCACATTTGAAAGCTATGAAGTTGTGATGCCTAGAGTGATTAAAT
CAAATGGTAAAAATGAGCCGTTTGATGAAGCCAAGTTGCGTCGCTCGTTGATGCATGCTTTACAAAAACGTCCTGTGACC
CAAGAGCAGATTGAAGCAGTCCTGAGTGATATTCAGCTAAAAATCCGTCGACTTGGCGAGCGAGATGTAAAATCACGTAT
GATTGGCGAGATTGTGATGCAGGCGCTGTTTGCATTGGATCATGTTGCTTATGTTCGCTTTGCCTCTGTTTATCAAGATT
TTCAGGATGTCGAAGCATTTCGCCGTCAGATCGAACAAATGCAGCAACGTGAACAGGAATGTGAGAAACATGATGTCTGA

Upstream 100 bases:

>100_bases
GCCGATCAGGCTGTTTTTTTATGGCGTTTTGTGGTCGAGATTCTGTAAGCGTTTAAATTTTGCTACACTAGCTTAAATAA
ATGAATTCATTTGAGCTGCC

Downstream 100 bases:

>100_bases
ACAAGAGCGTGATCATTACTGGATGTCACAGGCACTCGCACTGGCAAAAACTGCACAATTTCGCACACGTCCTAATCCTG
CGGTTGGCTGTGTGATTGTA

Product: NrdR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MHCPFCNAADSKVIDSRLAAEGCQIRRRRECISCGERFTTFESYEVVMPRVIKSNGKNEPFDEAKLRRSLMHALQKRPVT
QEQIEAVLSDIQLKIRRLGERDVKSRMIGEIVMQALFALDHVAYVRFASVYQDFQDVEAFRRQIEQMQQREQECEKHDV

Sequences:

>Translated_159_residues
MHCPFCNAADSKVIDSRLAAEGCQIRRRRECISCGERFTTFESYEVVMPRVIKSNGKNEPFDEAKLRRSLMHALQKRPVT
QEQIEAVLSDIQLKIRRLGERDVKSRMIGEIVMQALFALDHVAYVRFASVYQDFQDVEAFRRQIEQMQQREQECEKHDV
>Mature_159_residues
MHCPFCNAADSKVIDSRLAAEGCQIRRRRECISCGERFTTFESYEVVMPRVIKSNGKNEPFDEAKLRRSLMHALQKRPVT
QEQIEAVLSDIQLKIRRLGERDVKSRMIGEIVMQALFALDHVAYVRFASVYQDFQDVEAFRRQIEQMQQREQECEKHDV

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=54.7297297297297, Blast_Score=181, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_ACIAD (Q6FFE5)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045034.1
- STRING:   Q6FFE5
- GeneID:   2877821
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0246
- NMPDR:   fig|62977.3.peg.519
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q6FFE5
- ProtClustDB:   PRK00464
- BioCyc:   ASP62977:ACIAD0246-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18639; Mature: 18639

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCNAADSKVIDSRLAAEGCQIRRRRECISCGERFTTFESYEVVMPRVIKSNGKNEP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FDEAKLRRSLMHALQKRPVTQEQIEAVLSDIQLKIRRLGERDVKSRMIGEIVMQALFALD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVAYVRFASVYQDFQDVEAFRRQIEQMQQREQECEKHDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHCPFCNAADSKVIDSRLAAEGCQIRRRRECISCGERFTTFESYEVVMPRVIKSNGKNEP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FDEAKLRRSLMHALQKRPVTQEQIEAVLSDIQLKIRRLGERDVKSRMIGEIVMQALFALD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HVAYVRFASVYQDFQDVEAFRRQIEQMQQREQECEKHDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA