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The map label for this gene is tolQ [H]

Identifier: 49476144

GI number: 49476144

Start: 1707566

End: 1708279

Strand: Reverse

Name: tolQ [H]

Synonym: BH14870

Alternate gene names: 49476144

Gene position: 1708279-1707566 (Counterclockwise)

Preceding gene: 49476145

Following gene: 49476143

Centisome position: 88.46

GC content: 39.92

Gene sequence:

>714_bases
ATGCCGCATATAGAACTAACAAATCCAGAAACAATAGGCATAGTGCACTTGTTTATGCAAGCGGGTTTCGTTGTGAAAGC
TGTTATGATTGGGTTGCTGCTGGCTTCCATATGGAGTTGGGCAATTATTTTTGATAAAATCTTGACCTATCGGAGAATAC
GGCGTGAAATAAAACAATTTGAACGTATATTTTGGTCAGGGAAACCTCTTGAAGACCTTTATGCAACCTGTAAAAGTCAG
CGCACCAGTAGCATATCAGCGGTTTTTATGGCAGCAATGGTGGAATGGAAAAAATCTCTTGAAAAAGGAATCCATACATC
AATAAGTTTGCAGAGCAGGATTGATAAGGCTATGGATCTTATTTTAGGGCGTGAAAGCGCAAAAATAGAAGCAAAATTAA
GCTTTCTTGCTACACTTGGATCGGCTGGTCCTTTTATCGGCCTTTTTGGAACGGTTATTGGGATTATGGGGTCGTTTCTT
TCTATCTCTGCCTCTCAAAATACCTCATTGGCCATTGTTGCACCAGGTATTGCAGAGGCGCTTTTAGCAACTGCCATTGG
TTTGTTTGCTGCAATCCCAGCCGTTATTGCTTATAACAAATTTGTTAATGAAAGTGCACAAATTATTGCACAGATAGAAA
ACTTCGCCGATGAATTTTCGACAATTATCTCACGGCGTATTGATGAGACACTCACATCTCATTCACCATTATAA

Upstream 100 bases:

>100_bases
AAGACAAAGTGCAGTTTGTTTTGTTAAATTTAGAAACTATAAAACAATCTGTTTTATTGAATTTTAAGAAATGAAAGGTT
CATTTAGAGGGACAAAAATT

Downstream 100 bases:

>100_bases
AGAGGAGTTGTCTATGGGGATTTCTGTTGCTTCTTCTGCTCACAAAAACACACGCAGACGGCGTCGTTCACATAGCCAAC
TGATGAGTGAAATCAATGTC

Product: inner membrane tolQ protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MPHIELTNPETIGIVHLFMQAGFVVKAVMIGLLLASIWSWAIIFDKILTYRRIRREIKQFERIFWSGKPLEDLYATCKSQ
RTSSISAVFMAAMVEWKKSLEKGIHTSISLQSRIDKAMDLILGRESAKIEAKLSFLATLGSAGPFIGLFGTVIGIMGSFL
SISASQNTSLAIVAPGIAEALLATAIGLFAAIPAVIAYNKFVNESAQIIAQIENFADEFSTIISRRIDETLTSHSPL

Sequences:

>Translated_237_residues
MPHIELTNPETIGIVHLFMQAGFVVKAVMIGLLLASIWSWAIIFDKILTYRRIRREIKQFERIFWSGKPLEDLYATCKSQ
RTSSISAVFMAAMVEWKKSLEKGIHTSISLQSRIDKAMDLILGRESAKIEAKLSFLATLGSAGPFIGLFGTVIGIMGSFL
SISASQNTSLAIVAPGIAEALLATAIGLFAAIPAVIAYNKFVNESAQIIAQIENFADEFSTIISRRIDETLTSHSPL
>Mature_236_residues
PHIELTNPETIGIVHLFMQAGFVVKAVMIGLLLASIWSWAIIFDKILTYRRIRREIKQFERIFWSGKPLEDLYATCKSQR
TSSISAVFMAAMVEWKKSLEKGIHTSISLQSRIDKAMDLILGRESAKIEAKLSFLATLGSAGPFIGLFGTVIGIMGSFLS
ISASQNTSLAIVAPGIAEALLATAIGLFAAIPAVIAYNKFVNESAQIIAQIENFADEFSTIISRRIDETLTSHSPL

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=217, Percent_Identity=39.1705069124424, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1789381, Length=222, Percent_Identity=38.7387387387387, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014163 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 25966; Mature: 25835

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHIELTNPETIGIVHLFMQAGFVVKAVMIGLLLASIWSWAIIFDKILTYRRIRREIKQF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERIFWSGKPLEDLYATCKSQRTSSISAVFMAAMVEWKKSLEKGIHTSISLQSRIDKAMDL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILGRESAKIEAKLSFLATLGSAGPFIGLFGTVIGIMGSFLSISASQNTSLAIVAPGIAEA
HHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHH
LLATAIGLFAAIPAVIAYNKFVNESAQIIAQIENFADEFSTIISRRIDETLTSHSPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PHIELTNPETIGIVHLFMQAGFVVKAVMIGLLLASIWSWAIIFDKILTYRRIRREIKQF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERIFWSGKPLEDLYATCKSQRTSSISAVFMAAMVEWKKSLEKGIHTSISLQSRIDKAMDL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILGRESAKIEAKLSFLATLGSAGPFIGLFGTVIGIMGSFLSISASQNTSLAIVAPGIAEA
HHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHH
LLATAIGLFAAIPAVIAYNKFVNESAQIIAQIENFADEFSTIISRRIDETLTSHSPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]