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The map label for this gene is tolR [H]

Identifier: 49476143

GI number: 49476143

Start: 1707100

End: 1707552

Strand: Reverse

Name: tolR [H]

Synonym: BH14860

Alternate gene names: 49476143

Gene position: 1707552-1707100 (Counterclockwise)

Preceding gene: 49476144

Following gene: 49476142

Centisome position: 88.43

GC content: 41.28

Gene sequence:

>453_bases
ATGGGGATTTCTGTTGCTTCTTCTGCTCACAAAAACACACGCAGACGGCGTCGTTCACATAGCCAACTGATGAGTGAAAT
CAATGTCACACCTTTTGTTGATGTTATGCTGGTGCTGTTGATCATTTTCATGGTTTCTGCTCCACTTTTGGTGAATGGTG
TTCCGCTTGATTTGCCGCGTAGTCAAGCCGGACCGGTGCAAATGGAGAAAACGCCATTGACAGTTTCACTCGATGGGCAA
GGGCGCTTGGCTCTCAATCAAGACTATTATGAAACATTTGAAGCTTTGATTGCACAACTTAAGACTCTGCTTAAAACGGA
TGTTGAACAAAAAAAACAACGTATTTTTGTACGTGCTGCTAAAACTATTGAATATCAAAAAGTGTTACAATTGCTTGCTG
AACTTCAAAAAGCAGGTTTTTCACAGGTTGCTTTAGCAAGTCTAGCACAATAA

Upstream 100 bases:

>100_bases
GCACAGATAGAAAACTTCGCCGATGAATTTTCGACAATTATCTCACGGCGTATTGATGAGACACTCACATCTCATTCACC
ATTATAAAGAGGAGTTGTCT

Downstream 100 bases:

>100_bases
AATTTTTTAGAAACTATCGCTTGTTATTTGTAAAAACAACAAACAGTGATTAAAAGTGAAAAACGCAAGGCCATGGAGAT
GAACAGAGACTCTTATCATA

Product: tolR protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MGISVASSAHKNTRRRRRSHSQLMSEINVTPFVDVMLVLLIIFMVSAPLLVNGVPLDLPRSQAGPVQMEKTPLTVSLDGQ
GRLALNQDYYETFEALIAQLKTLLKTDVEQKKQRIFVRAAKTIEYQKVLQLLAELQKAGFSQVALASLAQ

Sequences:

>Translated_150_residues
MGISVASSAHKNTRRRRRSHSQLMSEINVTPFVDVMLVLLIIFMVSAPLLVNGVPLDLPRSQAGPVQMEKTPLTVSLDGQ
GRLALNQDYYETFEALIAQLKTLLKTDVEQKKQRIFVRAAKTIEYQKVLQLLAELQKAGFSQVALASLAQ
>Mature_149_residues
GISVASSAHKNTRRRRRSHSQLMSEINVTPFVDVMLVLLIIFMVSAPLLVNGVPLDLPRSQAGPVQMEKTPLTVSLDGQG
RLALNQDYYETFEALIAQLKTLLKTDVEQKKQRIFVRAAKTIEYQKVLQLLAELQKAGFSQVALASLAQ

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates [H]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1789380, Length=122, Percent_Identity=38.5245901639344, Blast_Score=86, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003400
- InterPro:   IPR014170 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 16691; Mature: 16560

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGISVASSAHKNTRRRRRSHSQLMSEINVTPFVDVMLVLLIIFMVSAPLLVNGVPLDLPR
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCC
SQAGPVQMEKTPLTVSLDGQGRLALNQDYYETFEALIAQLKTLLKTDVEQKKQRIFVRAA
CCCCCCEECCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTIEYQKVLQLLAELQKAGFSQVALASLAQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
GISVASSAHKNTRRRRRSHSQLMSEINVTPFVDVMLVLLIIFMVSAPLLVNGVPLDLPR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCC
SQAGPVQMEKTPLTVSLDGQGRLALNQDYYETFEALIAQLKTLLKTDVEQKKQRIFVRAA
CCCCCCEECCCCEEEEECCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTIEYQKVLQLLAELQKAGFSQVALASLAQ
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]