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The map label for this gene is dppB [H]

Identifier: 49475933

GI number: 49475933

Start: 1354774

End: 1355847

Strand: Reverse

Name: dppB [H]

Synonym: BH12170

Alternate gene names: 49475933

Gene position: 1355847-1354774 (Counterclockwise)

Preceding gene: 49475934

Following gene: 49475932

Centisome position: 70.21

GC content: 39.2

Gene sequence:

>1074_bases
ATGATTTTATCATTTCCAGAAGCAAGTGGAGAAATGTCACTACGGCAGAAAAATCTGCATGTATGGGCATTTTTTTTCAA
GGCATTTAAGCTGTTGGCTTCAGTCTTTATTACGTTGCTTGGTTTGGTGACTATTACTTTTTTTATTGGTCATCTTCTTC
CTTTAGATCCAGTTCTTGCTATTCTTGGTGATAATATCAGTCAGGAAGCTTATGATGCAATGTTTTATAAGTTGGGTCTT
GATAAGCCATTGATTGTCCAATATTGGAATTATCTTCATAATATAGCTTTGTTTGATTTTGGTGATGCTTTAACTTCGGG
GCGTCCTGTCTTAACAGATATTATGCGTGTATTTCCTGCAACCTTAGAGCTTGCAACAGTTGCTATTGTTATTGGTACGA
GTTTTGGTATTCCGTTTGGTGTCTTTGCCGCGATGTATCGCGATTCATTTATCGATTATTTTGTTCGTGTTTTTACACTC
CTGAGTTACTCAACGCCGACTTTTTGGCTTGGATTGATGGCGTTATTGGTATTTTATGCTAAGCTTGGTTGGATTGGTGG
ACCAGGCCGTCTTGATTTTCTTTACGAATATTCTTTTGAACAGAGAACAGGCTTTTTTCTTTGGGATACTGCAATGCAGG
GACAGTGGGAGGCTTTTGGCAATGTTTTTAGTCATATTATTATGCCTGCTTTAATCTTAGCTTTCGGTGCTATGGCCTAT
ATTAGTCGTATGACTCGTGGATTTATGATTGAACAACTTAATCAGGAATATATTATTACTGCACGTGTGAAAGGATTATC
TTGGATGCGAACGGTTTGGTTCCATGCTTTCCGCAATGCTGCTGTTCAGATTATCACTGTTGTTGGGCTTTCTTATGCTT
TTTTATTAGAAGGTGCCGTATTGACAGAGACAGTTTTCGCTTGGCCTGGTTTCGGACGTTACTTGACCAATGCTCTTTTG
GCAGGAGATATGAATGCAGTTGTTGGGTGCACGCTGCTAGTAGGGGGGCTCTTTGTTGCCATTAATTTATTTTCTGATTT
ACTTTATCGCATCTTTGATCCAAGGACACGCTGA

Upstream 100 bases:

>100_bases
AAGTAAAGAGTGTGTGGAGTGCTTGATTATAAATTTTTGACTGTGTGGCAAGAGGGGTGCCACACTAATATTTTATTAAG
TGTATGGGGATTTTATCAAG

Downstream 100 bases:

>100_bases
ATATGACTACTTCAATGAATCATCATAAACCGCAATCTTCATTTTCTTTAAGTTATTGGTTATATGAAGCTGTTCCGCGG
TCAATAGTTCAAGCGAACAT

Product: ABC transporter permease protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MILSFPEASGEMSLRQKNLHVWAFFFKAFKLLASVFITLLGLVTITFFIGHLLPLDPVLAILGDNISQEAYDAMFYKLGL
DKPLIVQYWNYLHNIALFDFGDALTSGRPVLTDIMRVFPATLELATVAIVIGTSFGIPFGVFAAMYRDSFIDYFVRVFTL
LSYSTPTFWLGLMALLVFYAKLGWIGGPGRLDFLYEYSFEQRTGFFLWDTAMQGQWEAFGNVFSHIIMPALILAFGAMAY
ISRMTRGFMIEQLNQEYIITARVKGLSWMRTVWFHAFRNAAVQIITVVGLSYAFLLEGAVLTETVFAWPGFGRYLTNALL
AGDMNAVVGCTLLVGGLFVAINLFSDLLYRIFDPRTR

Sequences:

>Translated_357_residues
MILSFPEASGEMSLRQKNLHVWAFFFKAFKLLASVFITLLGLVTITFFIGHLLPLDPVLAILGDNISQEAYDAMFYKLGL
DKPLIVQYWNYLHNIALFDFGDALTSGRPVLTDIMRVFPATLELATVAIVIGTSFGIPFGVFAAMYRDSFIDYFVRVFTL
LSYSTPTFWLGLMALLVFYAKLGWIGGPGRLDFLYEYSFEQRTGFFLWDTAMQGQWEAFGNVFSHIIMPALILAFGAMAY
ISRMTRGFMIEQLNQEYIITARVKGLSWMRTVWFHAFRNAAVQIITVVGLSYAFLLEGAVLTETVFAWPGFGRYLTNALL
AGDMNAVVGCTLLVGGLFVAINLFSDLLYRIFDPRTR
>Mature_357_residues
MILSFPEASGEMSLRQKNLHVWAFFFKAFKLLASVFITLLGLVTITFFIGHLLPLDPVLAILGDNISQEAYDAMFYKLGL
DKPLIVQYWNYLHNIALFDFGDALTSGRPVLTDIMRVFPATLELATVAIVIGTSFGIPFGVFAAMYRDSFIDYFVRVFTL
LSYSTPTFWLGLMALLVFYAKLGWIGGPGRLDFLYEYSFEQRTGFFLWDTAMQGQWEAFGNVFSHIIMPALILAFGAMAY
ISRMTRGFMIEQLNQEYIITARVKGLSWMRTVWFHAFRNAAVQIITVVGLSYAFLLEGAVLTETVFAWPGFGRYLTNALL
AGDMNAVVGCTLLVGGLFVAINLFSDLLYRIFDPRTR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=333, Percent_Identity=40.5405405405405, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI1787761, Length=294, Percent_Identity=42.1768707482993, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1789888, Length=280, Percent_Identity=35.7142857142857, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1787053, Length=334, Percent_Identity=31.437125748503, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787550, Length=260, Percent_Identity=33.8461538461538, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787497, Length=321, Percent_Identity=28.3489096573209, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788504, Length=306, Percent_Identity=26.4705882352941, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 40292; Mature: 40292

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSFPEASGEMSLRQKNLHVWAFFFKAFKLLASVFITLLGLVTITFFIGHLLPLDPVLA
CEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ILGDNISQEAYDAMFYKLGLDKPLIVQYWNYLHNIALFDFGDALTSGRPVLTDIMRVFPA
HHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHH
TLELATVAIVIGTSFGIPFGVFAAMYRDSFIDYFVRVFTLLSYSTPTFWLGLMALLVFYA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KLGWIGGPGRLDFLYEYSFEQRTGFFLWDTAMQGQWEAFGNVFSHIIMPALILAFGAMAY
HHCCCCCCCCEEHEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISRMTRGFMIEQLNQEYIITARVKGLSWMRTVWFHAFRNAAVQIITVVGLSYAFLLEGAV
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LTETVFAWPGFGRYLTNALLAGDMNAVVGCTLLVGGLFVAINLFSDLLYRIFDPRTR
HHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MILSFPEASGEMSLRQKNLHVWAFFFKAFKLLASVFITLLGLVTITFFIGHLLPLDPVLA
CEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
ILGDNISQEAYDAMFYKLGLDKPLIVQYWNYLHNIALFDFGDALTSGRPVLTDIMRVFPA
HHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHH
TLELATVAIVIGTSFGIPFGVFAAMYRDSFIDYFVRVFTLLSYSTPTFWLGLMALLVFYA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
KLGWIGGPGRLDFLYEYSFEQRTGFFLWDTAMQGQWEAFGNVFSHIIMPALILAFGAMAY
HHCCCCCCCCEEHEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISRMTRGFMIEQLNQEYIITARVKGLSWMRTVWFHAFRNAAVQIITVVGLSYAFLLEGAV
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LTETVFAWPGFGRYLTNALLAGDMNAVVGCTLLVGGLFVAINLFSDLLYRIFDPRTR
HHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]