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The map label for this gene is pdxJ [H]

Identifier: 49475824

GI number: 49475824

Start: 1198646

End: 1199380

Strand: Reverse

Name: pdxJ [H]

Synonym: BH10900

Alternate gene names: 49475824

Gene position: 1199380-1198646 (Counterclockwise)

Preceding gene: 49475825

Following gene: 49475823

Centisome position: 62.11

GC content: 40.14

Gene sequence:

>735_bases
ATGGCAGTAAAACTTTCGGTTAATCTCAATGCTGTTGCTGTTTTACGCAATCGACGTAATCTTCCATGGCCAAATATAAA
GAGTATTGGGCATATAGCGCTTACAGCTGGCGCAGCAGGTTTGACGGTTCATCCGCGACCGGATGAACGACATATTCGTT
TTGCTGATTTGCCAGATATACGTTGTTTAATTAACAGCGCTTTTCCTACTGCAGAGTTTAATATTGAAGGTTATCCAAGC
GATAGATTTTTGGATTTGGCAGAAAAATATGCTGATCAGATTACCCTTGTCCCTGATGATCCAGCTCAATCAACCTCCGA
TCATGGTTGGGATTTTGCTCATAATGCGGAATTTTTGGCGCCTATTATTCAACGCTTGAAAGAAAAGAAAATTCGTGTGT
CGTTATTCGCTAATCCTCTTGTAGATGGCCTTGACATTGCTAAAACAATTGGTGCTGATCGTGTGGAGTTTTATACTGGA
CCTTATGGTGGTGCATTTAAAGATAAGACAAAACAGGATCAAGAGTTGAAGAAACTTATTTTAGCGGCAAGAAAGGCCAA
AGAGCTGCAATTAGGTGTTAATGCAGGTCATGATCTGACAATTACTAACCTTCCTGCTCTTGTTAATCATATTTCTTGGC
TTGATGAAGTCTCTATTGGTCATGGGCTTATTGCTGATGCATTAGAATACGGAATGTATGAGACTGTTCAGCGTTTCATC
CGGTTATTGTCTTAA

Upstream 100 bases:

>100_bases
AACCATTGTTCGATAGAGAAAATTATTTTTATTATCTGGGCTTATGCTGTGAAATGTATTTTTTTCTATCTTTTAATTAT
GTATGCAAATGGGAATATGT

Downstream 100 bases:

>100_bases
TTCTTTTCTCCTTTATTCAATTTTATGAATGAGATTTTATAAAACTCTACAAATTCTGATTCATAAGAATAATTTTGCAT
ATGTTTGATAAAGAATAGAG

Product: pyridoxine 5'-phosphate synthase

Products: NA

Alternate protein names: PNP synthase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MAVKLSVNLNAVAVLRNRRNLPWPNIKSIGHIALTAGAAGLTVHPRPDERHIRFADLPDIRCLINSAFPTAEFNIEGYPS
DRFLDLAEKYADQITLVPDDPAQSTSDHGWDFAHNAEFLAPIIQRLKEKKIRVSLFANPLVDGLDIAKTIGADRVEFYTG
PYGGAFKDKTKQDQELKKLILAARKAKELQLGVNAGHDLTITNLPALVNHISWLDEVSIGHGLIADALEYGMYETVQRFI
RLLS

Sequences:

>Translated_244_residues
MAVKLSVNLNAVAVLRNRRNLPWPNIKSIGHIALTAGAAGLTVHPRPDERHIRFADLPDIRCLINSAFPTAEFNIEGYPS
DRFLDLAEKYADQITLVPDDPAQSTSDHGWDFAHNAEFLAPIIQRLKEKKIRVSLFANPLVDGLDIAKTIGADRVEFYTG
PYGGAFKDKTKQDQELKKLILAARKAKELQLGVNAGHDLTITNLPALVNHISWLDEVSIGHGLIADALEYGMYETVQRFI
RLLS
>Mature_243_residues
AVKLSVNLNAVAVLRNRRNLPWPNIKSIGHIALTAGAAGLTVHPRPDERHIRFADLPDIRCLINSAFPTAEFNIEGYPSD
RFLDLAEKYADQITLVPDDPAQSTSDHGWDFAHNAEFLAPIIQRLKEKKIRVSLFANPLVDGLDIAKTIGADRVEFYTGP
YGGAFKDKTKQDQELKKLILAARKAKELQLGVNAGHDLTITNLPALVNHISWLDEVSIGHGLIADALEYGMYETVQRFIR
LLS

Specific function: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate [H]

COG id: COG0854

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788917, Length=240, Percent_Identity=34.1666666666667, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR004569 [H]

Pfam domain/function: PF03740 PdxJ [H]

EC number: =2.6.99.2 [H]

Molecular weight: Translated: 27099; Mature: 26968

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKLSVNLNAVAVLRNRRNLPWPNIKSIGHIALTAGAAGLTVHPRPDERHIRFADLPDI
CEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEECCCCCCCCEEECCCCHH
RCLINSAFPTAEFNIEGYPSDRFLDLAEKYADQITLVPDDPAQSTSDHGWDFAHNAEFLA
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCHHHH
PIIQRLKEKKIRVSLFANPLVDGLDIAKTIGADRVEFYTGPYGGAFKDKTKQDQELKKLI
HHHHHHHHHHEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHH
LAARKAKELQLGVNAGHDLTITNLPALVNHISWLDEVSIGHGLIADALEYGMYETVQRFI
HHHHHHHHEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RLLS
HHHC
>Mature Secondary Structure 
AVKLSVNLNAVAVLRNRRNLPWPNIKSIGHIALTAGAAGLTVHPRPDERHIRFADLPDI
EEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCEECCCCCCCCEEECCCCHH
RCLINSAFPTAEFNIEGYPSDRFLDLAEKYADQITLVPDDPAQSTSDHGWDFAHNAEFLA
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCCCCHHHH
PIIQRLKEKKIRVSLFANPLVDGLDIAKTIGADRVEFYTGPYGGAFKDKTKQDQELKKLI
HHHHHHHHHHEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHH
LAARKAKELQLGVNAGHDLTITNLPALVNHISWLDEVSIGHGLIADALEYGMYETVQRFI
HHHHHHHHEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RLLS
HHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA