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The map label for this gene is fur2 [H]

Identifier: 49475010

GI number: 49475010

Start: 267701

End: 268117

Strand: Reverse

Name: fur2 [H]

Synonym: BH01980

Alternate gene names: 49475010

Gene position: 268117-267701 (Counterclockwise)

Preceding gene: 49475011

Following gene: 49475009

Centisome position: 13.88

GC content: 36.93

Gene sequence:

>417_bases
ATGCATAAAAAGCGAAATTATGAGCAAGAATTACGCACTGCAGGTTTAAGAGTGACACGTCAACGACGTATTATTCTTGA
TATTTTGGTCGACACAAAAGATCATCCTAATGCATTTGAAATTTTTCAACGTGCTAACAAAATAGATTCCAGTATTTCGC
TCTCAACTGTTTACAGAACCATGAAGATATTAGAAGGAAATGGGACGATTCATCGCCATAGTTTTAGTGGTGGTCCCTCT
CGTTTTGAGCAAGCAGATGGGCACCACCATGATCATCTCATTGATTTGGAAACAGGGCAAGTTATCGAATTTCATTCTGA
TATTATTGAAAAGTTGCAAGAAGAAATCGCTAAGTCCCTTGGTTATGATATTATCCATCACCGCCTTGAACTTTATGGGA
AAAAACGTAATTTTTAA

Upstream 100 bases:

>100_bases
CATGGGGGAAAGTGGGACGGAATGAACGTTGTCCTTGTGGTTCAGAAAAAAAATACAAACATTGTCACGGCGCCTTCGTC
TGAAAAATATAACAGTTAAG

Downstream 100 bases:

>100_bases
AATTATAGTTTCTCATGTGTCATCAAAAAATTCTTCCTGCAAACAAGATTTTACACAAGTTCTCTTTAAAAGCCTGCAGT
TTCCATTGGCAAGAAAGATT

Product: Iron response regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MHKKRNYEQELRTAGLRVTRQRRIILDILVDTKDHPNAFEIFQRANKIDSSISLSTVYRTMKILEGNGTIHRHSFSGGPS
RFEQADGHHHDHLIDLETGQVIEFHSDIIEKLQEEIAKSLGYDIIHHRLELYGKKRNF

Sequences:

>Translated_138_residues
MHKKRNYEQELRTAGLRVTRQRRIILDILVDTKDHPNAFEIFQRANKIDSSISLSTVYRTMKILEGNGTIHRHSFSGGPS
RFEQADGHHHDHLIDLETGQVIEFHSDIIEKLQEEIAKSLGYDIIHHRLELYGKKRNF
>Mature_138_residues
MHKKRNYEQELRTAGLRVTRQRRIILDILVDTKDHPNAFEIFQRANKIDSSISLSTVYRTMKILEGNGTIHRHSFSGGPS
RFEQADGHHHDHLIDLETGQVIEFHSDIIEKLQEEIAKSLGYDIIHHRLELYGKKRNF

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=124, Percent_Identity=43.5483870967742, Blast_Score=97, Evalue=3e-22,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16155; Mature: 16155

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKKRNYEQELRTAGLRVTRQRRIILDILVDTKDHPNAFEIFQRANKIDSSISLSTVYRT
CCCCCCHHHHHHHHHHHHHHHHHHEEHEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
MKILEGNGTIHRHSFSGGPSRFEQADGHHHDHLIDLETGQVIEFHSDIIEKLQEEIAKSL
HHHHCCCCCEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
GYDIIHHRLELYGKKRNF
CHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHKKRNYEQELRTAGLRVTRQRRIILDILVDTKDHPNAFEIFQRANKIDSSISLSTVYRT
CCCCCCHHHHHHHHHHHHHHHHHHEEHEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
MKILEGNGTIHRHSFSGGPSRFEQADGHHHDHLIDLETGQVIEFHSDIIEKLQEEIAKSL
HHHHCCCCCEEECCCCCCCHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHH
GYDIIHHRLELYGKKRNF
CHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA