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The map label for this gene is ispA [C]

Identifier: 46447630

GI number: 46447630

Start: 2377971

End: 2378780

Strand: Reverse

Name: ispA [C]

Synonym: pc1996

Alternate gene names: 46447630

Gene position: 2378780-2377971 (Counterclockwise)

Preceding gene: 46447631

Following gene: 46447622

Centisome position: 98.52

GC content: 38.15

Gene sequence:

>810_bases
TTGGGTGATAAAACATCATTAAGAGATGCTTGTGAATATGCGTTACTAAATGGTGGAAAACGATTTAGACCTGCTCTCGT
TTTGATGATTGCTAAAGCCCTTGGTTTTCAAGTCGATGTTTCACAGGCTGCTTTATGTGTAGAATACTTTCATACTGCGT
CTTTGATTGCAGATGATTTGCCTTGTATGGATAACGATGATGAACGGCGAAATGCTCCTACCTTACATAAAATTTTTGGG
GAATCGACTTCTCTTTTGGCGACCTATACTTTGATTGCCGCTGGCTACGCTTGCTTAGCTCGGAATACCGCGATTTTGAA
AGATAGTGCACACCCCTACGTTAATCAAAAAGAGCGTTTATGTGTATTGGCTTTAGAAAATGCAACGCAAAATACGGGAA
TTTTAGGGGCAACGGGGGGACAATATTTAGATTTAAATCCTCCTAATCTTTCTTTAAAGACTTTAAAAGAAGTGATTGAA
AAGAAAACGGTTACGTTATTTGAAATTTCTTTTGTCTTAGGGTGGATTTTTGGAGGAGGGGTTTTGGAAAAGTTGTCCCT
CGTGAAAAAATGTGCAGGACACTTTGGAATGGCTTTCCAAATTGCCGATGACTTGGGAGACATGAAGCAAGACTCCTTTC
ATGATCACACAATGAATTTTGCAAATGTTTATGGTAAACCAGCTGCGACTCAATTATTTCATGACGAAATTCATCAATTT
AATCAAACACTAACTGCGCTTGATTTTCAATCAGAAGATCTTCAAGCTTTAACTTGCCTTCTTATTGAGCAAGTACAACT
TCTTTCTTGA

Upstream 100 bases:

>100_bases
TATTTGAGCTTTTATGCAAACAACCAAACCGTCTTTTCATTCAATTTTAGAACCTTATAAGTCTCATGTTGAACAAATTA
TCCAAAATAATATGGATTGT

Downstream 100 bases:

>100_bases
GCTTTGTGAGATTGGGAGAATTATAACCTGATTCGCAAGATGACTCTAGCTATAAATGATAGAAAAGGCTGTGTATACAT
GAGGTACGCAAAGTATAGCC

Product: putative geranyltranstransferase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MGDKTSLRDACEYALLNGGKRFRPALVLMIAKALGFQVDVSQAALCVEYFHTASLIADDLPCMDNDDERRNAPTLHKIFG
ESTSLLATYTLIAAGYACLARNTAILKDSAHPYVNQKERLCVLALENATQNTGILGATGGQYLDLNPPNLSLKTLKEVIE
KKTVTLFEISFVLGWIFGGGVLEKLSLVKKCAGHFGMAFQIADDLGDMKQDSFHDHTMNFANVYGKPAATQLFHDEIHQF
NQTLTALDFQSEDLQALTCLLIEQVQLLS

Sequences:

>Translated_269_residues
MGDKTSLRDACEYALLNGGKRFRPALVLMIAKALGFQVDVSQAALCVEYFHTASLIADDLPCMDNDDERRNAPTLHKIFG
ESTSLLATYTLIAAGYACLARNTAILKDSAHPYVNQKERLCVLALENATQNTGILGATGGQYLDLNPPNLSLKTLKEVIE
KKTVTLFEISFVLGWIFGGGVLEKLSLVKKCAGHFGMAFQIADDLGDMKQDSFHDHTMNFANVYGKPAATQLFHDEIHQF
NQTLTALDFQSEDLQALTCLLIEQVQLLS
>Mature_268_residues
GDKTSLRDACEYALLNGGKRFRPALVLMIAKALGFQVDVSQAALCVEYFHTASLIADDLPCMDNDDERRNAPTLHKIFGE
STSLLATYTLIAAGYACLARNTAILKDSAHPYVNQKERLCVLALENATQNTGILGATGGQYLDLNPPNLSLKTLKEVIEK
KTVTLFEISFVLGWIFGGGVLEKLSLVKKCAGHFGMAFQIADDLGDMKQDSFHDHTMNFANVYGKPAATQLFHDEIHQFN
QTLTALDFQSEDLQALTCLLIEQVQLLS

Specific function: Unknown

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786623, Length=270, Percent_Identity=32.2222222222222, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 29564; Mature: 29433

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDKTSLRDACEYALLNGGKRFRPALVLMIAKALGFQVDVSQAALCVEYFHTASLIADDL
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHCC
PCMDNDDERRNAPTLHKIFGESTSLLATYTLIAAGYACLARNTAILKDSAHPYVNQKERL
CCCCCCHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCE
CVLALENATQNTGILGATGGQYLDLNPPNLSLKTLKEVIEKKTVTLFEISFVLGWIFGGG
EEEEECCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VLEKLSLVKKCAGHFGMAFQIADDLGDMKQDSFHDHTMNFANVYGKPAATQLFHDEIHQF
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
NQTLTALDFQSEDLQALTCLLIEQVQLLS
HHHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GDKTSLRDACEYALLNGGKRFRPALVLMIAKALGFQVDVSQAALCVEYFHTASLIADDL
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHCC
PCMDNDDERRNAPTLHKIFGESTSLLATYTLIAAGYACLARNTAILKDSAHPYVNQKERL
CCCCCCHHHCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCE
CVLALENATQNTGILGATGGQYLDLNPPNLSLKTLKEVIEKKTVTLFEISFVLGWIFGGG
EEEEECCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VLEKLSLVKKCAGHFGMAFQIADDLGDMKQDSFHDHTMNFANVYGKPAATQLFHDEIHQF
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
NQTLTALDFQSEDLQALTCLLIEQVQLLS
HHHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486607; 7918490 [H]