Click here to switch to the map view.

The map label for this gene is glmU [H]

Identifier: 46447631

GI number: 46447631

Start: 2379041

End: 2379721

Strand: Reverse

Name: glmU [H]

Synonym: pc1997

Alternate gene names: 46447631

Gene position: 2379721-2379041 (Counterclockwise)

Preceding gene: 46447634

Following gene: 46447630

Centisome position: 98.56

GC content: 38.33

Gene sequence:

>681_bases
ATGGATATTAAATCTTCTGATTTCTTCAATCTCTCTACCTTCACTCATACCGCTCTTTTTGAAAAAGATCCGGCACCTTG
GATTATTTTAACTCGATTAGCTTCTTATTTAAAGAAATTAAAATTAGGCGTGCTCTTAGGTTCTATTTCTCCTCAAGCCT
ATTTAATTCGTCCAGAAGAAATTACTATTGGAGAAGGATCAATTGTGGAGCCTGGCGCCTATATTCAAGGTCCTTGTTGG
ATTGGTAATCATTGTGTGATTCGCCATGGCGCTTATATTAGAGGCTATGTCATTACAGGAGATTATTGCGTGATAGGGCA
TGATACTGAGGTCAAAAATAGCTTATTTCTAAATCGTGCGCATGCAGCTCACTTTGCTTACGTGGGAGATACTATTTTAG
GACATGATGTGAATTTAGGCGCAGGGACGAAATGTGCAAACTTTAAATTAGATCAACAAACCGTCTCTGTTGTTTATAAA
CATCAGCACTTCGATACTCAGCTTCGTAAATTTGGAGCGATTATTGGAGATAGAAGTCAAATCGGTTGTAATACAGTCAC
AAATCCTGGTTCTTTGATTGGAATGGACGTTAGAGCTTACCCTTGTTTAAATATCGGCGGTTGGATTCCTCATCGTTCTA
TCGTCAAACCTGGCTCTCAAGTTCGAATTTCTTCTTATTAA

Upstream 100 bases:

>100_bases
TATAATATATTCTTCTTTAGAGAAAGCTGTGGAAATCTTATTTGCTTCATGAGAAGATTTAGAATCTTATTAACTGTGCT
TTGGAAACAATCGTCACTCT

Downstream 100 bases:

>100_bases
TTTAAAACCTGTTTTAATCACCTGGAATTTTGGGAAATAAATTCGTTATCAGTACAACTTTTTTTTTCAGAAAACTTGAC
CGGTAGAGAAAATGTATCGC

Product: putative UDP-N-acetylglucosamine diphosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MDIKSSDFFNLSTFTHTALFEKDPAPWIILTRLASYLKKLKLGVLLGSISPQAYLIRPEEITIGEGSIVEPGAYIQGPCW
IGNHCVIRHGAYIRGYVITGDYCVIGHDTEVKNSLFLNRAHAAHFAYVGDTILGHDVNLGAGTKCANFKLDQQTVSVVYK
HQHFDTQLRKFGAIIGDRSQIGCNTVTNPGSLIGMDVRAYPCLNIGGWIPHRSIVKPGSQVRISSY

Sequences:

>Translated_226_residues
MDIKSSDFFNLSTFTHTALFEKDPAPWIILTRLASYLKKLKLGVLLGSISPQAYLIRPEEITIGEGSIVEPGAYIQGPCW
IGNHCVIRHGAYIRGYVITGDYCVIGHDTEVKNSLFLNRAHAAHFAYVGDTILGHDVNLGAGTKCANFKLDQQTVSVVYK
HQHFDTQLRKFGAIIGDRSQIGCNTVTNPGSLIGMDVRAYPCLNIGGWIPHRSIVKPGSQVRISSY
>Mature_226_residues
MDIKSSDFFNLSTFTHTALFEKDPAPWIILTRLASYLKKLKLGVLLGSISPQAYLIRPEEITIGEGSIVEPGAYIQGPCW
IGNHCVIRHGAYIRGYVITGDYCVIGHDTEVKNSLFLNRAHAAHFAYVGDTILGHDVNLGAGTKCANFKLDQQTVSVVYK
HQHFDTQLRKFGAIIGDRSQIGCNTVTNPGSLIGMDVRAYPCLNIGGWIPHRSIVKPGSQVRISSY

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 24876; Mature: 24876

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKSSDFFNLSTFTHTALFEKDPAPWIILTRLASYLKKLKLGVLLGSISPQAYLIRPEE
CCCCCCCCEEEHHHEEEEEECCCCCCEEHHHHHHHHHHHHHHHEEEECCCCCEEEEECCE
ITIGEGSIVEPGAYIQGPCWIGNHCVIRHGAYIRGYVITGDYCVIGHDTEVKNSLFLNRA
EEECCCCEECCCCEEECCEEECCEEEEECCCEEEEEEEECCEEEEECCCCCCHHEEEEHH
HAAHFAYVGDTILGHDVNLGAGTKCANFKLDQQTVSVVYKHQHFDTQLRKFGAIIGDRSQ
HHEEEEEECCEEECCCCCCCCCCEEECEEECHHHEEEEHHHHHHHHHHHHHHHHHCCCCC
IGCNTVTNPGSLIGMDVRAYPCLNIGGWIPHRSIVKPGSQVRISSY
CCCCCCCCCCCEEEEEEEECCEECCCCCCCCHHHCCCCCEEEEECC
>Mature Secondary Structure
MDIKSSDFFNLSTFTHTALFEKDPAPWIILTRLASYLKKLKLGVLLGSISPQAYLIRPEE
CCCCCCCCEEEHHHEEEEEECCCCCCEEHHHHHHHHHHHHHHHEEEECCCCCEEEEECCE
ITIGEGSIVEPGAYIQGPCWIGNHCVIRHGAYIRGYVITGDYCVIGHDTEVKNSLFLNRA
EEECCCCEECCCCEEECCEEECCEEEEECCCEEEEEEEECCEEEEECCCCCCHHEEEEHH
HAAHFAYVGDTILGHDVNLGAGTKCANFKLDQQTVSVVYKHQHFDTQLRKFGAIIGDRSQ
HHEEEEEECCEEECCCCCCCCCCEEECEEECHHHEEEEHHHHHHHHHHHHHHHHHCCCCC
IGCNTVTNPGSLIGMDVRAYPCLNIGGWIPHRSIVKPGSQVRISSY
CCCCCCCCCCCEEEEEEEECCEECCCCCCCCHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]