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The map label for this gene is efp

Identifier: 46447163

GI number: 46447163

Start: 1833395

End: 1833967

Strand: Direct

Name: efp

Synonym: pc1529

Alternate gene names: 46447163

Gene position: 1833395-1833967 (Clockwise)

Preceding gene: 46447160

Following gene: 46447164

Centisome position: 75.93

GC content: 38.74

Gene sequence:

>573_bases
ATGGCACAAATGAGCACAAGCGAAATCAGGGGTGGAGTAAAGGTAGAGGTCGAAGCACAACCCTACACTATCATCAGTAA
TGAATTTGTCAAACCAGGTAAAGGGCAAGCCTTTAACCGCATTAAAATGAAACATTTATTAACAGGACGTGTCATCGAGC
GTACATTCAAGTCCGGAGAAAAGTTAAATCTTGCTGATGTTGCCGAAGAAGAAATGCGAATGCTTTACAAAGAAAGTGAT
GGGGTCATCTTTATGGATGAGAAAAGCTTCGAACAAATTAAGATTTCTTTAGAAAGCATTGGAGAGACTGTACAATGGTT
ATTAGACGATCATGTCTATGAAGTGATTTTTTACAATGGAAATGCCGTTAACGTTGAACCTCCTACATTTATGGAAATGG
TTATTACAGATACTTCTCCTGGCGTTAGAGGAGATACGGCATCAGGTAGAGTTTTAAAACCAGCTATATTGGAAAGCGGT
GCAAAAGTTCAAGTTCCTATTTTTGTAGAGCAAGGTGAAAAAATTAAAGTAGACACTCGTACTGGAGAATATGTTTCGCG
AGTTTCGAGCTAA

Upstream 100 bases:

>100_bases
TTTTATATTTATCAAACGCGAATTTAGAATAAGTAATGGATTTTTTTACTTATTTCTAATCCCGTTATCAAAATAAGATT
TTAGCAAAGGAATGTGATCT

Downstream 100 bases:

>100_bases
TCAGTGCAACTGTCTAAAATTTCAAGATTACATGATCGAGCTACCATGCTCGGTCAATCCCGTCAATTTTTTGCAGCCCG
CCAAATTTTGGAAGTTGATT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 2

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MAQMSTSEIRGGVKVEVEAQPYTIISNEFVKPGKGQAFNRIKMKHLLTGRVIERTFKSGEKLNLADVAEEEMRMLYKESD
GVIFMDEKSFEQIKISLESIGETVQWLLDDHVYEVIFYNGNAVNVEPPTFMEMVITDTSPGVRGDTASGRVLKPAILESG
AKVQVPIFVEQGEKIKVDTRTGEYVSRVSS

Sequences:

>Translated_190_residues
MAQMSTSEIRGGVKVEVEAQPYTIISNEFVKPGKGQAFNRIKMKHLLTGRVIERTFKSGEKLNLADVAEEEMRMLYKESD
GVIFMDEKSFEQIKISLESIGETVQWLLDDHVYEVIFYNGNAVNVEPPTFMEMVITDTSPGVRGDTASGRVLKPAILESG
AKVQVPIFVEQGEKIKVDTRTGEYVSRVSS
>Mature_189_residues
AQMSTSEIRGGVKVEVEAQPYTIISNEFVKPGKGQAFNRIKMKHLLTGRVIERTFKSGEKLNLADVAEEEMRMLYKESDG
VIFMDEKSFEQIKISLESIGETVQWLLDDHVYEVIFYNGNAVNVEPPTFMEMVITDTSPGVRGDTASGRVLKPAILESGA
KVQVPIFVEQGEKIKVDTRTGEYVSRVSS

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=47.3404255319149, Blast_Score=186, Evalue=6e-49,
Organism=Escherichia coli, GI87082061, Length=152, Percent_Identity=24.3421052631579, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP2_PARUW (Q6MAZ6)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008528.1
- ProteinModelPortal:   Q6MAZ6
- SMR:   Q6MAZ6
- STRING:   Q6MAZ6
- GeneID:   2781178
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1529
- NMPDR:   fig|264201.1.peg.1529
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   Q6MAZ6
- ProtClustDB:   PRK00529
- BioCyc:   CPRO264201:PC1529-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21240; Mature: 21108

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQMSTSEIRGGVKVEVEAQPYTIISNEFVKPGKGQAFNRIKMKHLLTGRVIERTFKSGE
CCCCCCHHHCCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KLNLADVAEEEMRMLYKESDGVIFMDEKSFEQIKISLESIGETVQWLLDDHVYEVIFYNG
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
NAVNVEPPTFMEMVITDTSPGVRGDTASGRVLKPAILESGAKVQVPIFVEQGEKIKVDTR
CEEEECCCCEEEEEEECCCCCCCCCCCCCCEECHHHHCCCCEEEEEEEEECCCEEEEECC
TGEYVSRVSS
CCHHHHHHCC
>Mature Secondary Structure 
AQMSTSEIRGGVKVEVEAQPYTIISNEFVKPGKGQAFNRIKMKHLLTGRVIERTFKSGE
CCCCCHHHCCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
KLNLADVAEEEMRMLYKESDGVIFMDEKSFEQIKISLESIGETVQWLLDDHVYEVIFYNG
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECC
NAVNVEPPTFMEMVITDTSPGVRGDTASGRVLKPAILESGAKVQVPIFVEQGEKIKVDTR
CEEEECCCCEEEEEEECCCCCCCCCCCCCCEECHHHHCCCCEEEEEEEEECCCEEEEECC
TGEYVSRVSS
CCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA